| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the ETC-206_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAT1 | FAT atypical cadherin 1 | 0.151547 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.133983 |
| AHNAK | AHNAK nucleoprotein | 0.0737202 |
| ENO1 | enolase 1, (alpha) | 0.0517448 |
| MCL1 | myeloid cell leukemia 1 | 0.0431484 |
| POTEF | POTE ankyrin domain family, member F | 0.0415176 |
| ACTG1 | actin gamma 1 | 0.0401287 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0369831 |
| HSPA8 | heat shock 70kDa protein 8 | 0.033339 |
| RPL3 | ribosomal protein L3 | 0.0331593 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0313484 |
| INTS6 | integrator complex subunit 6 | 0.0295422 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0284121 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0273894 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0268421 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0256163 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0236747 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232911 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0232086 |
| DIAPH1 | diaphanous-related formin 1 | 0.0228441 |
| HOMER1 | homer scaffolding protein 1 | 0.0224855 |
| EGFR | epidermal growth factor receptor | 0.0224365 |
| TPM3 | tropomyosin 3 | 0.0221569 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0217698 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0216451 |
| WWOX | WW domain containing oxidoreductase | 0.0216063 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0208681 |
| EGR1 | early growth response 1 | 0.0204972 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0199491 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0192401 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0188523 |
| DSPP | dentin sialophosphoprotein | 0.018786 |
| PCBP2 | poly(rC) binding protein 2 | 0.0185357 |
| FLNA | filamin A, alpha | 0.0183741 |
| KRT8 | keratin 8, type II | 0.0182385 |
| ASPH | aspartate beta-hydroxylase | 0.0182339 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0179923 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0179807 |
| PKM | pyruvate kinase, muscle | 0.017776 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0176971 |
| PLEC | plectin | 0.0175271 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0174908 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0170493 |
| SEPTIN9 | septin 9 | 0.017039 |
| IPO7 | importin 7 | 0.0169879 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0168415 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0165813 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0164568 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0164524 |
| YAP1 | Yes-associated protein 1 | 0.0159874 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0157991 |
| RRM2 | ribonucleotide reductase M2 | 0.0157407 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0157337 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0155444 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0155234 |
| VCL | vinculin | 0.0151549 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0151148 |
| KRT18 | keratin 18, type I | 0.014736 |
| MYO6 | myosin VI | 0.0147278 |
| ITGA6 | integrin, alpha 6 | 0.0145424 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0144031 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0143985 |
| RPL4 | ribosomal protein L4 | 0.0143035 |
| LRRC23 | leucine rich repeat containing 23 | 0.0142201 |
| VEGFA | vascular endothelial growth factor A | 0.0141707 |
| DST | dystonin | 0.0138367 |
| PALD1 | phosphatase domain containing, paladin 1 | 0.013752 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0136353 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.013501 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0132428 |
| AEBP2 | AE binding protein 2 | 0.0129614 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0128913 |
| TGFB1 | transforming growth factor, beta 1 | 0.0128677 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0127908 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0127318 |
| GPC5 | glypican 5 | 0.0126711 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.012507 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.012464 |
| PCDH7 | protocadherin 7 | 0.012442 |
| SMAD3 | SMAD family member 3 | 0.0123573 |
| FAM120A | family with sequence similarity 120A | 0.0121667 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0120426 |
| SKI | SKI proto-oncogene | 0.0120204 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0119189 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0117377 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0117343 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0114671 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0113769 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0112361 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.011153 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0110456 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0108572 |
| HELLS | helicase, lymphoid-specific | 0.0108215 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.010815 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0107231 |
| APP | amyloid beta (A4) precursor protein | 0.0106151 |
| RNF213 | ring finger protein 213 | 0.0105953 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0104528 |
| JUN | jun proto-oncogene | 0.0104408 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0104277 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.465525 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.237416 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.19757 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.098001 |
| FTL | ferritin, light polypeptide | -0.0941988 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0881625 |
| GOLGA4 | golgin A4 | -0.0856859 |
| RPS6 | ribosomal protein S6 | -0.0842686 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0825868 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0696621 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0626272 |
| CANX | calnexin | -0.0618547 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0607335 |
| RPL35A | ribosomal protein L35a | -0.0595421 |
| TMSB10 | thymosin beta 10 | -0.0591926 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0575443 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0560212 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0540511 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0517451 |
| HDLBP | high density lipoprotein binding protein | -0.0515564 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0507533 |
| RPL34 | ribosomal protein L34 | -0.0496604 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0492801 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0485986 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0484654 |
| NDRG1 | N-myc downstream regulated 1 | -0.0482215 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0476092 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0473882 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0458896 |
| NF1 | neurofibromin 1 | -0.0456385 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0451198 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0444179 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0440003 |
| RBM39 | RNA binding motif protein 39 | -0.0439983 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0436881 |
| WDR45B | WD repeat domain 45B | -0.0433365 |
| OGA | O-GlcNAcase | -0.0433086 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0431266 |
| MORF4L2 | mortality factor 4 like 2 | -0.0430145 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.042514 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.042246 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0421138 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0412861 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0407851 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0407798 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0405923 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0405036 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0404251 |
| RPS24 | ribosomal protein S24 | -0.0403373 |
| PRELID2 | PRELI domain containing 2 | -0.0399391 |
| ARF4 | ADP-ribosylation factor 4 | -0.0396704 |
| SRP54 | signal recognition particle 54kDa | -0.0396479 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0396403 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0394696 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0393273 |
| CCNI | cyclin I | -0.0388616 |
| RPLP1 | ribosomal protein, large, P1 | -0.0385642 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.038476 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0379056 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.036474 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0359177 |
| RPLP0 | ribosomal protein, large, P0 | -0.0355242 |
| NOP58 | NOP58 ribonucleoprotein | -0.0355094 |
| S100A10 | S100 calcium binding protein A10 | -0.035193 |
| FDPS | farnesyl diphosphate synthase | -0.0351539 |
| RPS8 | ribosomal protein S8 | -0.0351086 |
| TXNRD1 | thioredoxin reductase 1 | -0.0347026 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0345661 |
| TMEM263 | transmembrane protein 263 | -0.0341551 |
| ZNF292 | zinc finger protein 292 | -0.0341056 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0339245 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0335963 |
| RPL11 | ribosomal protein L11 | -0.033563 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0335034 |
| RIOK3 | RIO kinase 3 | -0.0333794 |
| RPS19 | ribosomal protein S19 | -0.0330544 |
| SETD5 | SET domain containing 5 | -0.0330416 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0329936 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0326778 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0326049 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.032501 |
| RLF | rearranged L-myc fusion | -0.0324576 |
| GNAS | GNAS complex locus | -0.0323442 |
| HM13 | histocompatibility (minor) 13 | -0.0322117 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0320383 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0317929 |
| ARF1 | ADP-ribosylation factor 1 | -0.0316729 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.031623 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0316096 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0314586 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0313893 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0313195 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0311635 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0307513 |
| JMJD1C | jumonji domain containing 1C | -0.0305323 |
| WASF2 | WAS protein family, member 2 | -0.0303819 |
| RRBP1 | ribosome binding protein 1 | -0.0302121 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0300655 |
| SUCO | SUN domain containing ossification factor | -0.0300608 |
| TMEM41B | transmembrane protein 41B | -0.0300143 |
