| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0973874 |
| ENO1 | enolase 1, (alpha) | 0.0627575 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0497698 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0411409 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342988 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0301716 |
| MT2A | metallothionein 2A | 0.0301276 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0283587 |
| AHNAK | AHNAK nucleoprotein | 0.0277893 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0273327 |
| RPL3 | ribosomal protein L3 | 0.0266114 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0247886 |
| POTEF | POTE ankyrin domain family, member F | 0.0240576 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0239251 |
| RPS12 | ribosomal protein S12 | 0.023451 |
| PCBP2 | poly(rC) binding protein 2 | 0.023387 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0226912 |
| TPM3 | tropomyosin 3 | 0.0221741 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0210736 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0206989 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.019322 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0189005 |
| SET | SET nuclear proto-oncogene | 0.0188446 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0179504 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0165714 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.016553 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0160911 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0160908 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0157084 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0155827 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.014684 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0143288 |
| RPL37A | ribosomal protein L37a | 0.0138842 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0128976 |
| YBX1 | Y box binding protein 1 | 0.0128524 |
| RPS3 | ribosomal protein S3 | 0.012405 |
| TMF1 | TATA element modulatory factor 1 | 0.0123472 |
| L1CAM | L1 cell adhesion molecule | 0.0122354 |
| CAPRIN2 | caprin family member 2 | 0.0122282 |
| PLEC | plectin | 0.0121841 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0116936 |
| CENPF | centromere protein F, 350/400kDa | 0.0115738 |
| MSN | moesin | 0.0115222 |
| RPS2 | ribosomal protein S2 | 0.0113 |
| JAG1 | jagged 1 | 0.0112701 |
| DSPP | dentin sialophosphoprotein | 0.0112448 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0112325 |
| RPS7 | ribosomal protein S7 | 0.0111745 |
| LDHA | lactate dehydrogenase A | 0.0111573 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0110278 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.010754 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0103338 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0102858 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0102532 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.0100126 |
| RPL4 | ribosomal protein L4 | 0.00994913 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00964399 |
| TLN1 | talin 1 | 0.00956761 |
| SRSF5 | serine/arginine-rich splicing factor 5 | 0.00956696 |
| GRAMD1B | GRAM domain containing 1B | 0.00951441 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00950018 |
| TSPYL2 | TSPY-like 2 | 0.00902591 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00894839 |
| AXL | AXL receptor tyrosine kinase | 0.00878404 |
| IPO7 | importin 7 | 0.00872715 |
| COL5A3 | collagen, type V, alpha 3 | 0.00864612 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00861831 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.00851616 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.008423 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.00840923 |
| VEGFA | vascular endothelial growth factor A | 0.00838223 |
| RPL30 | ribosomal protein L30 | 0.00837845 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.00830587 |
| FAM120A | family with sequence similarity 120A | 0.00826777 |
| DSTN | destrin (actin depolymerizing factor) | 0.00825522 |
| RBBP7 | retinoblastoma binding protein 7 | 0.00813943 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00813003 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.00811823 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0080709 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.00802154 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.00795154 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00783037 |
| MAMLD1 | mastermind-like domain containing 1 | 0.00782038 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00778174 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00769613 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.00761073 |
| PGM3 | phosphoglucomutase 3 | 0.00757784 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00749072 |
| CLDND1 | claudin domain containing 1 | 0.00747176 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.00740361 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.00736361 |
| TRIB1 | tribbles pseudokinase 1 | 0.00733744 |
| TGOLN2 | trans-golgi network protein 2 | 0.00732382 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.00728678 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00721271 |
| FSCN2 | fascin actin-bundling protein 2, retinal | 0.00718923 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.00711657 |
| F2R | coagulation factor II (thrombin) receptor | 0.0070933 |
| COL4A1 | collagen, type IV, alpha 1 | 0.00707502 |
| RND3 | Rho family GTPase 3 | 0.00705919 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.412292 |
| VIM | vimentin | -0.277792 |
| TMSB10 | thymosin beta 10 | -0.122685 |
| FN1 | fibronectin 1 | -0.121833 |
| IGF2 | insulin-like growth factor 2 | -0.115021 |
| PTMA | prothymosin, alpha | -0.10693 |
| CDH13 | cadherin 13 | -0.10127 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0988601 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0953623 |
| NDRG1 | N-myc downstream regulated 1 | -0.0770884 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0765686 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0759256 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0704053 |
| ASPH | aspartate beta-hydroxylase | -0.0679861 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0649828 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.05267 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0510958 |
| EGR1 | early growth response 1 | -0.0501982 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0501105 |
| HMGA2 | high mobility group AT-hook 2 | -0.049735 |
| RPL35A | ribosomal protein L35a | -0.0493381 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0493031 |
| CCND1 | cyclin D1 | -0.0491169 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0459679 |
| COL1A1 | collagen, type I, alpha 1 | -0.0449653 |
| S100A10 | S100 calcium binding protein A10 | -0.0445069 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0435724 |
| IER3 | immediate early response 3 | -0.042156 |
| RPS24 | ribosomal protein S24 | -0.0412164 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0403405 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0395812 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0394961 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.038398 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0372219 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0370679 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0359331 |
| RPS6 | ribosomal protein S6 | -0.0358882 |
| RPL34 | ribosomal protein L34 | -0.0357803 |
| FMN1 | formin 1 | -0.0356188 |
| CAVIN1 | caveolae associated protein 1 | -0.0351741 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0350683 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.034318 |
| RAD51B | RAD51 paralog B | -0.0329931 |
| NAV1 | neuron navigator 1 | -0.0323722 |
| CDCP1 | CUB domain containing protein 1 | -0.0323531 |
| RRBP1 | ribosome binding protein 1 | -0.0322776 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0313729 |
| MAP4 | microtubule-associated protein 4 | -0.0310138 |
| TUBB6 | tubulin, beta 6 class V | -0.0306938 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0299903 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0293383 |
| RPL38 | ribosomal protein L38 | -0.0290941 |
| FRMD4A | FERM domain containing 4A | -0.0288824 |
| PGK1 | phosphoglycerate kinase 1 | -0.0287183 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0286686 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.028649 |
| PRKCA | protein kinase C, alpha | -0.0283968 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0283668 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.028301 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0280243 |
| GNAS | GNAS complex locus | -0.0275558 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0273717 |
| RPS16 | ribosomal protein S16 | -0.0272781 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0269727 |
| ATXN1 | ataxin 1 | -0.0268 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0267755 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0266209 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0265471 |
| ACTG1 | actin gamma 1 | -0.0264801 |
| DIAPH2 | diaphanous-related formin 2 | -0.0262089 |
| RPLP1 | ribosomal protein, large, P1 | -0.0261075 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0257761 |
| RPLP2 | ribosomal protein, large, P2 | -0.0252899 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0252318 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0247657 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.024503 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0243352 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0242508 |
| ADM | adrenomedullin | -0.0241664 |
| RPS21 | ribosomal protein S21 | -0.0240341 |
| RUNX1 | runt-related transcription factor 1 | -0.0239784 |
| CUX1 | cut-like homeobox 1 | -0.0239003 |
| PTK2 | protein tyrosine kinase 2 | -0.02371 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0232201 |
| COL5A1 | collagen, type V, alpha 1 | -0.0232117 |
| HLA-B | major histocompatibility complex, class I, B | -0.0231584 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0229783 |
| EMP1 | epithelial membrane protein 1 | -0.0227419 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0226745 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0223028 |
| MYO10 | myosin X | -0.0221018 |
| TMEM263 | transmembrane protein 263 | -0.0219078 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0218173 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0217811 |
| HM13 | histocompatibility (minor) 13 | -0.0217307 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0216861 |
| JMJD1C | jumonji domain containing 1C | -0.0213054 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.02122 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0211508 |
| ASTN2 | astrotactin 2 | -0.0210181 |
