| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the ETC-206_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.176387 |
| EXT1 | exostosin glycosyltransferase 1 | 0.132819 |
| VEGFA | vascular endothelial growth factor A | 0.104978 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104434 |
| AHNAK | AHNAK nucleoprotein | 0.101897 |
| FN1 | fibronectin 1 | 0.100897 |
| ENO1 | enolase 1, (alpha) | 0.0975785 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0948494 |
| CD44 | CD44 molecule (Indian blood group) | 0.0816687 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.078306 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0683181 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0661932 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0594741 |
| CALR | calreticulin | 0.0581873 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0581318 |
| ACTG1 | actin gamma 1 | 0.0577777 |
| HMGA2 | high mobility group AT-hook 2 | 0.0568218 |
| POTEF | POTE ankyrin domain family, member F | 0.0566031 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0562298 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0560193 |
| CDH13 | cadherin 13 | 0.0550598 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0517585 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0515417 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0502557 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0502018 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0498482 |
| ASPH | aspartate beta-hydroxylase | 0.047961 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0479348 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.045907 |
| LDHA | lactate dehydrogenase A | 0.0450121 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.044016 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0438245 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0430736 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0430554 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0424721 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0416136 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0415769 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0408312 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0396138 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.039612 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0390532 |
| MSN | moesin | 0.0379417 |
| VCL | vinculin | 0.0364343 |
| MYO10 | myosin X | 0.0353769 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0352917 |
| GLIS3 | GLIS family zinc finger 3 | 0.0351047 |
| ECE1 | endothelin converting enzyme 1 | 0.0342772 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0339661 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0337857 |
| MAP1B | microtubule-associated protein 1B | 0.0336259 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.032175 |
| NAV1 | neuron navigator 1 | 0.0315193 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0312679 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0308368 |
| FAT1 | FAT atypical cadherin 1 | 0.0296208 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0289998 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0288423 |
| JAG1 | jagged 1 | 0.0274784 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0271255 |
| RPL3 | ribosomal protein L3 | 0.027123 |
| APP | amyloid beta (A4) precursor protein | 0.0269697 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0269103 |
| IL6ST | interleukin 6 signal transducer | 0.0268264 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0265304 |
| SDC2 | syndecan 2 | 0.0264679 |
| CTSB | cathepsin B | 0.0264431 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0260919 |
| INHBA | inhibin, beta A | 0.0258244 |
| SVIL | supervillin | 0.0258125 |
| HDAC9 | histone deacetylase 9 | 0.0257563 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0257286 |
| MT1X | metallothionein 1X | 0.0256282 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0256259 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0256213 |
| DST | dystonin | 0.0254344 |
| AXL | AXL receptor tyrosine kinase | 0.0252884 |
| PLSCR1 | phospholipid scramblase 1 | 0.0250118 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0245729 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0242306 |
| FBN1 | fibrillin 1 | 0.0238799 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0235268 |
| SLC25A51 | solute carrier family 25, member 51 | 0.023203 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0230487 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0229539 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0228346 |
| SP100 | SP100 nuclear antigen | 0.0226267 |
| CLIC4 | chloride intracellular channel 4 | 0.0225499 |
| VCAN | versican | 0.0225073 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0224709 |
| NOTCH2 | notch 2 | 0.022133 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0220359 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0217684 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0214261 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0214027 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0209038 |
| FOXP1 | forkhead box P1 | 0.0205605 |
| JAK2 | Janus kinase 2 | 0.0204031 |
| ZNF644 | zinc finger protein 644 | 0.0199485 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0199408 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0199016 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.285159 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.191909 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141344 |
| IER3 | immediate early response 3 | -0.140891 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.129 |
| COL1A1 | collagen, type I, alpha 1 | -0.126863 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.106978 |
| CADM1 | cell adhesion molecule 1 | -0.0836698 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0831347 |
| FTL | ferritin, light polypeptide | -0.0634612 |
| CAVIN1 | caveolae associated protein 1 | -0.0617083 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0582602 |
| RPL35A | ribosomal protein L35a | -0.0575522 |
| COL1A2 | collagen, type I, alpha 2 | -0.0564808 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0531309 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0522492 |
| PTMA | prothymosin, alpha | -0.0493723 |
| RPS8 | ribosomal protein S8 | -0.0473098 |
| LOXL2 | lysyl oxidase-like 2 | -0.0458521 |
| RPL37A | ribosomal protein L37a | -0.0447519 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0429566 |
| TMSB10 | thymosin beta 10 | -0.0429279 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0428552 |
| ADM | adrenomedullin | -0.0428072 |
| PDE10A | phosphodiesterase 10A | -0.0424825 |
| RPS12 | ribosomal protein S12 | -0.0422905 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0422317 |
| GNAS | GNAS complex locus | -0.0421737 |
| RPS6 | ribosomal protein S6 | -0.0418227 |
| VIM | vimentin | -0.04073 |
| LOX | lysyl oxidase | -0.0406315 |
| RPL11 | ribosomal protein L11 | -0.0396932 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0389942 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0383841 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0381208 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0369557 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0365605 |
| RRBP1 | ribosome binding protein 1 | -0.0365243 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0359712 |
| TPM4 | tropomyosin 4 | -0.0357955 |
| GOLGA4 | golgin A4 | -0.0349872 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0348012 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0347755 |
| ZNF292 | zinc finger protein 292 | -0.0347523 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0345955 |
| RPL12 | ribosomal protein L12 | -0.0344636 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0340589 |
| HLA-B | major histocompatibility complex, class I, B | -0.0339639 |
| COL5A1 | collagen, type V, alpha 1 | -0.0334314 |
| LAMB3 | laminin, beta 3 | -0.0332769 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0329049 |
| RPL26 | ribosomal protein L26 | -0.032822 |
| RPS24 | ribosomal protein S24 | -0.0327989 |
| SPAG9 | sperm associated antigen 9 | -0.0325575 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0319072 |
| MT2A | metallothionein 2A | -0.0316713 |
| OGA | O-GlcNAcase | -0.0314431 |
| RPL13A | ribosomal protein L13a | -0.031364 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0311106 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0309601 |
| RPL31 | ribosomal protein L31 | -0.0306161 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0300861 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0300793 |
| RPS27A | ribosomal protein S27a | -0.0296093 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0291579 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.028951 |
| RPL9 | ribosomal protein L9 | -0.0283956 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.027971 |
| RPL37 | ribosomal protein L37 | -0.0279014 |
| RPL38 | ribosomal protein L38 | -0.0278987 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0277396 |
| RPS3 | ribosomal protein S3 | -0.0277129 |
| STC1 | stanniocalcin 1 | -0.0274944 |
| RPLP1 | ribosomal protein, large, P1 | -0.0263336 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0260154 |
| RLF | rearranged L-myc fusion | -0.02592 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0254786 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0253477 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0253386 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0252805 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0250228 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0250193 |
| RPS20 | ribosomal protein S20 | -0.0249059 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0246854 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0246185 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0244025 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0237401 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.023613 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.023554 |
| RBM39 | RNA binding motif protein 39 | -0.0234908 |
| FBXO32 | F-box protein 32 | -0.0232658 |
| ATP13A3 | ATPase type 13A3 | -0.0232441 |
| RPS25 | ribosomal protein S25 | -0.0231582 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.023064 |
| RTN4 | reticulon 4 | -0.0230174 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0228893 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0227933 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.02277 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0227035 |
| TMEM41B | transmembrane protein 41B | -0.0226478 |
