| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.138363 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0710482 |
| AHNAK | AHNAK nucleoprotein | 0.0705688 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0571652 |
| SMAD3 | SMAD family member 3 | 0.0552957 |
| DST | dystonin | 0.0474997 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0454749 |
| PDZD8 | PDZ domain containing 8 | 0.0451478 |
| NTN4 | netrin 4 | 0.0442465 |
| PLK2 | polo-like kinase 2 | 0.0431726 |
| ACTG1 | actin gamma 1 | 0.0406239 |
| FAT1 | FAT atypical cadherin 1 | 0.040464 |
| ANXA11 | annexin A11 | 0.040442 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.036281 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0354091 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.033435 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0328572 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0324724 |
| MYOF | myoferlin | 0.0322824 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0317191 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.031222 |
| EREG | epiregulin | 0.030667 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0292045 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0287329 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0280049 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276872 |
| RPL3 | ribosomal protein L3 | 0.0273858 |
| POTEF | POTE ankyrin domain family, member F | 0.0269445 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0263714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261633 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0254112 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0246122 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0245247 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0244168 |
| WWC1 | WW and C2 domain containing 1 | 0.0232779 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231851 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0217768 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0212734 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0208179 |
| KRT18 | keratin 18, type I | 0.0202994 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0201563 |
| MYO5B | myosin VB | 0.0194278 |
| AXIN2 | axin 2 | 0.0191581 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0191552 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0191176 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190763 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0190066 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.018922 |
| TMEM123 | transmembrane protein 123 | 0.0188841 |
| ETV6 | ets variant 6 | 0.0187611 |
| YAP1 | Yes-associated protein 1 | 0.0185552 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0182792 |
| UTRN | utrophin | 0.0180148 |
| AFDN | afadin, adherens junction formation factor | 0.0175323 |
| MYADM | myeloid-associated differentiation marker | 0.0173344 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0171031 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0170388 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0169905 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0168667 |
| GOLM1 | golgi membrane protein 1 | 0.0166995 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0165008 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0161493 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0157117 |
| CAB39 | calcium binding protein 39 | 0.0155863 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0152603 |
| PCBP2 | poly(rC) binding protein 2 | 0.0151738 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0149631 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0147359 |
| FOXO1 | forkhead box O1 | 0.0145793 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.01453 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0141083 |
| MYZAP | myocardial zonula adherens protein | 0.014059 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0140187 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0139637 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0138956 |
| SHROOM3 | shroom family member 3 | 0.0136689 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0134509 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0134236 |
| TLE4 | transducin-like enhancer of split 4 | 0.0134206 |
| CLIC5 | chloride intracellular channel 5 | 0.0133729 |
| ATP9A | ATPase, class II, type 9A | 0.0133123 |
| KRT17 | keratin 17, type I | 0.0132291 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0131032 |
| LATS2 | large tumor suppressor kinase 2 | 0.0130882 |
| FOXP1 | forkhead box P1 | 0.0129504 |
| CLMN | calmin (calponin-like, transmembrane) | 0.012917 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0127633 |
| SYNJ2 | synaptojanin 2 | 0.0126392 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0124793 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0123869 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.012379 |
| ARHGAP17 | Rho GTPase activating protein 17 | 0.0122805 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0121654 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0121535 |
| CCNYL1 | cyclin Y-like 1 | 0.01213 |
| SIK3 | SIK family kinase 3 | 0.0119748 |
| ARRDC4 | arrestin domain containing 4 | 0.0119216 |
| SLTM | SAFB-like, transcription modulator | 0.0117082 |
| EXPH5 | exophilin 5 | 0.0116139 |
| TGFA | transforming growth factor, alpha | 0.0114952 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.18343 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.124563 |
| PTMA | prothymosin, alpha | -0.108031 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1069 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0954282 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0942376 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0894818 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0885503 |
| TMSB10 | thymosin beta 10 | -0.0880412 |
| FTL | ferritin, light polypeptide | -0.0792833 |
| EGR1 | early growth response 1 | -0.0746691 |
| RPS6 | ribosomal protein S6 | -0.073296 |
| ANXA2 | annexin A2 | -0.0717651 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0715641 |
| LAMA4 | laminin, alpha 4 | -0.0709908 |
| INTS6 | integrator complex subunit 6 | -0.0686139 |
| RPL35A | ribosomal protein L35a | -0.066274 |
| RPS24 | ribosomal protein S24 | -0.0638992 |
| RPS12 | ribosomal protein S12 | -0.0629383 |
| RPLP1 | ribosomal protein, large, P1 | -0.0628261 |
| FRY | furry homolog (Drosophila) | -0.0614665 |
| RPS3 | ribosomal protein S3 | -0.0609376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0575336 |
| RPLP2 | ribosomal protein, large, P2 | -0.0574933 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0553445 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0530799 |
| SQSTM1 | sequestosome 1 | -0.0511404 |
| AGR2 | anterior gradient 2 | -0.0509902 |
| RPL37A | ribosomal protein L37a | -0.0499862 |
| RPS8 | ribosomal protein S8 | -0.049548 |
| RPS27A | ribosomal protein S27a | -0.0491045 |
| PTK2 | protein tyrosine kinase 2 | -0.0490684 |
| RPS13 | ribosomal protein S13 | -0.0489565 |
| RPS19 | ribosomal protein S19 | -0.0471088 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0469354 |
| RPL34 | ribosomal protein L34 | -0.0468126 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0465663 |
| RPS25 | ribosomal protein S25 | -0.0453877 |
| RPL9 | ribosomal protein L9 | -0.0444879 |
| ACTN4 | actinin, alpha 4 | -0.0437587 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0430194 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0427844 |
| KRT20 | keratin 20, type I | -0.0414693 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0412419 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0411302 |
| RPL11 | ribosomal protein L11 | -0.0409752 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0405894 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0403537 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0400709 |
| RPS16 | ribosomal protein S16 | -0.0400559 |
| RPL31 | ribosomal protein L31 | -0.0398562 |
| GNAS | GNAS complex locus | -0.0394404 |
| LYZ | lysozyme | -0.0386924 |
| RPL13A | ribosomal protein L13a | -0.0385993 |
| MCL1 | myeloid cell leukemia 1 | -0.0381316 |
| B2M | beta-2-microglobulin | -0.0380888 |
| RPS23 | ribosomal protein S23 | -0.0379672 |
| RPL12 | ribosomal protein L12 | -0.0377201 |
| FOXO3 | forkhead box O3 | -0.0376466 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0369867 |
| RPS17 | ribosomal protein S17 | -0.036925 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0365412 |
| HM13 | histocompatibility (minor) 13 | -0.0365141 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0362071 |
| PRELID2 | PRELI domain containing 2 | -0.0356812 |
| RPL23 | ribosomal protein L23 | -0.035604 |
| RPL26 | ribosomal protein L26 | -0.0354826 |
| RPL19 | ribosomal protein L19 | -0.0354266 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0353397 |
| NF1 | neurofibromin 1 | -0.0353057 |
| RTN3 | reticulon 3 | -0.0351124 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0347013 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0343546 |
| RPL37 | ribosomal protein L37 | -0.0342748 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0341938 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0339711 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0338332 |
| SDC4 | syndecan 4 | -0.0336548 |
| DIAPH2 | diaphanous-related formin 2 | -0.0336441 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0328572 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0325316 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0324892 |
| S100A6 | S100 calcium binding protein A6 | -0.0324164 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0321174 |
| PGK1 | phosphoglycerate kinase 1 | -0.0313939 |
| GOLGB1 | golgin B1 | -0.0311977 |
| RPL27A | ribosomal protein L27a | -0.0311908 |
| S100P | S100 calcium binding protein P | -0.0311561 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0308978 |
| TMEM65 | transmembrane protein 65 | -0.0305267 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0303722 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0300572 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0300506 |
| RPS21 | ribosomal protein S21 | -0.0298348 |
| DGKH | diacylglycerol kinase, eta | -0.0296656 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0296398 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0295148 |
| CANX | calnexin | -0.0291058 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0289553 |
| RPS11 | ribosomal protein S11 | -0.0287554 |
