| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the ETC-206_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0770105 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.076297 |
| LMO7 | LIM domain 7 | 0.0531904 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.051857 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.051417 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0486082 |
| MYOF | myoferlin | 0.0476106 |
| GDA | guanine deaminase | 0.0465533 |
| DSPP | dentin sialophosphoprotein | 0.0433183 |
| TMC5 | transmembrane channel-like 5 | 0.0411861 |
| HSPA8 | heat shock 70kDa protein 8 | 0.039581 |
| MACC1 | metastasis associated in colon cancer 1 | 0.037875 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0284833 |
| POTEF | POTE ankyrin domain family, member F | 0.0270142 |
| AHNAK | AHNAK nucleoprotein | 0.0253386 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | 0.0229024 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0222379 |
| FAT1 | FAT atypical cadherin 1 | 0.0216699 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0206603 |
| SEPTIN9 | septin 9 | 0.0205028 |
| PCBP2 | poly(rC) binding protein 2 | 0.0203939 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0195334 |
| SMAD3 | SMAD family member 3 | 0.0193199 |
| EZR | ezrin | 0.0187773 |
| ANXA1 | annexin A1 | 0.0181107 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0180004 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0168803 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.016835 |
| MGAM2 | maltase-glucoamylase 2 (putative) | 0.0167166 |
| ASPH | aspartate beta-hydroxylase | 0.0166551 |
| RBM47 | RNA binding motif protein 47 | 0.0166212 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0165749 |
| LIPH | lipase, member H | 0.0164694 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0163224 |
| RNF213 | ring finger protein 213 | 0.0161365 |
| ANXA11 | annexin A11 | 0.0160473 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0154784 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0151634 |
| RPL3 | ribosomal protein L3 | 0.0150996 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0150894 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0149829 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0147911 |
| GOLM1 | golgi membrane protein 1 | 0.0146576 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0146425 |
| DST | dystonin | 0.0142508 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0136956 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0136807 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0134979 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0134037 |
| LIMA1 | LIM domain and actin binding 1 | 0.0132483 |
| USP6NL | USP6 N-terminal like | 0.0132405 |
| APP | amyloid beta (A4) precursor protein | 0.013155 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0131374 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0130095 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0129969 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0129336 |
| MUC17 | mucin 17, cell surface associated | 0.0128505 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0122347 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.012231 |
| PRSS3 | protease, serine, 3 | 0.0120366 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0119301 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0117077 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0113433 |
| KRT19 | keratin 19, type I | 0.0111002 |
| ITGB8 | integrin, beta 8 | 0.0110736 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0109363 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0109287 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0109154 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0108937 |
| PLS1 | plastin 1 | 0.010838 |
| TMEM45B | transmembrane protein 45B | 0.010752 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0106208 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0106104 |
| EFNA5 | ephrin-A5 | 0.0105197 |
| STK24 | serine/threonine kinase 24 | 0.0102361 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0101967 |
| PARD6B | par-6 family cell polarity regulator beta | 0.0101699 |
| SGMS2 | sphingomyelin synthase 2 | 0.010051 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0099942 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.00997991 |
| AFDN | afadin, adherens junction formation factor | 0.00997914 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.00990658 |
| RPS7 | ribosomal protein S7 | 0.00977906 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00964425 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0096346 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00960301 |
| FLNA | filamin A, alpha | 0.00960207 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00956823 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00951509 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00902366 |
| PLEC | plectin | 0.00901174 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.00898199 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00892408 |
| TPM3 | tropomyosin 3 | 0.00882431 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.00875751 |
| SET | SET nuclear proto-oncogene | 0.00872391 |
| TSPAN3 | tetraspanin 3 | 0.0087059 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.00867379 |
| MYZAP | myocardial zonula adherens protein | 0.00851117 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00847425 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.259742 |
| NPSR1 | neuropeptide S receptor 1 | -0.202965 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.156476 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.148333 |
| TMSB10 | thymosin beta 10 | -0.134543 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129282 |
| PTMA | prothymosin, alpha | -0.127694 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.125013 |
| RPS6 | ribosomal protein S6 | -0.117041 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.10546 |
| AGR2 | anterior gradient 2 | -0.0948148 |
| RPL35A | ribosomal protein L35a | -0.0938388 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0778456 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0757274 |
| FTL | ferritin, light polypeptide | -0.0685258 |
| RPS25 | ribosomal protein S25 | -0.0650446 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0622986 |
| AREG | amphiregulin | -0.057483 |
| RPS24 | ribosomal protein S24 | -0.0564834 |
| RPLP1 | ribosomal protein, large, P1 | -0.0539209 |
| EMP1 | epithelial membrane protein 1 | -0.0537376 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0537052 |
| H1-0 | H1.0 linker histone | -0.052701 |
| KLHL29 | kelch-like family member 29 | -0.0519788 |
| RPS8 | ribosomal protein S8 | -0.0518773 |
| GOLGA4 | golgin A4 | -0.0514732 |
| RPL34 | ribosomal protein L34 | -0.0511021 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0508197 |
| HM13 | histocompatibility (minor) 13 | -0.050167 |
| S100A6 | S100 calcium binding protein A6 | -0.0496555 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0492423 |
| RPL23 | ribosomal protein L23 | -0.0491966 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0489445 |
| S100A10 | S100 calcium binding protein A10 | -0.0486588 |
| RPL19 | ribosomal protein L19 | -0.0485819 |
| TMEM123 | transmembrane protein 123 | -0.0484656 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0483921 |
| NDRG1 | N-myc downstream regulated 1 | -0.0483495 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0469196 |
| TES | testin LIM domain protein | -0.0466458 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0456479 |
| RPS19 | ribosomal protein S19 | -0.0454611 |
| WDR45B | WD repeat domain 45B | -0.0454241 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0438661 |
| RPS21 | ribosomal protein S21 | -0.0425879 |
| HLA-A | major histocompatibility complex, class I, A | -0.0420387 |
| RPL12 | ribosomal protein L12 | -0.0412271 |
| RPS16 | ribosomal protein S16 | -0.0410032 |
| EHBP1 | EH domain binding protein 1 | -0.0409098 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0397609 |
| CANX | calnexin | -0.0394954 |
| RPL26 | ribosomal protein L26 | -0.0394689 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0389315 |
| RPS3 | ribosomal protein S3 | -0.038664 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0383065 |
| S100P | S100 calcium binding protein P | -0.037386 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0371535 |
| RPL37A | ribosomal protein L37a | -0.0368363 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0367364 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0359334 |
| HMGA1 | high mobility group AT-hook 1 | -0.0356812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0355143 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0352709 |
| RPL38 | ribosomal protein L38 | -0.0348082 |
| RPL11 | ribosomal protein L11 | -0.0344417 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0344317 |
| RPS27A | ribosomal protein S27a | -0.0342742 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0342706 |
| B2M | beta-2-microglobulin | -0.0342581 |
| RPL8 | ribosomal protein L8 | -0.0341732 |
| GNAS | GNAS complex locus | -0.0340695 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0338986 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0338082 |
| RPS29 | ribosomal protein S29 | -0.0332321 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0330143 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0328836 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0328219 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0323103 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0322736 |
| SETD5 | SET domain containing 5 | -0.0322193 |
| RPS11 | ribosomal protein S11 | -0.0322012 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0320706 |
| TFRC | transferrin receptor | -0.0318845 |
| HLA-E | major histocompatibility complex, class I, E | -0.0318023 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0315841 |
| CDK6 | cyclin-dependent kinase 6 | -0.031462 |
| ATXN1 | ataxin 1 | -0.0312582 |
| CDK13 | cyclin-dependent kinase 13 | -0.0310816 |
| CUX1 | cut-like homeobox 1 | -0.0310781 |
| PGK1 | phosphoglycerate kinase 1 | -0.0310503 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0308492 |
| RPS5 | ribosomal protein S5 | -0.0307486 |
| HDLBP | high density lipoprotein binding protein | -0.0307294 |
| ANXA2 | annexin A2 | -0.0303995 |
| RPL9 | ribosomal protein L9 | -0.0301947 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0301196 |
| CCND1 | cyclin D1 | -0.0300882 |
| MORF4L2 | mortality factor 4 like 2 | -0.0300584 |
| RPL28 | ribosomal protein L28 | -0.0300188 |
| RPS17 | ribosomal protein S17 | -0.0298882 |
