| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.18533 |
| FAT1 | FAT atypical cadherin 1 | 0.14758 |
| ENO1 | enolase 1, (alpha) | 0.0832139 |
| LDHA | lactate dehydrogenase A | 0.0799792 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0787988 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.076625 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0756897 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0731944 |
| POTEF | POTE ankyrin domain family, member F | 0.0697223 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0649824 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0635982 |
| RPL3 | ribosomal protein L3 | 0.061908 |
| DSPP | dentin sialophosphoprotein | 0.059425 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0592811 |
| TXNIP | thioredoxin interacting protein | 0.0582175 |
| ACTG1 | actin gamma 1 | 0.0536345 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0532713 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0473066 |
| LMO7 | LIM domain 7 | 0.0442347 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0427959 |
| PCBP2 | poly(rC) binding protein 2 | 0.0411763 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0403671 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0403451 |
| PKM | pyruvate kinase, muscle | 0.0403147 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0402279 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0397841 |
| PDZD8 | PDZ domain containing 8 | 0.0370799 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0369879 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.036621 |
| RPL4 | ribosomal protein L4 | 0.0364687 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.036094 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0354873 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0353744 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0346834 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0335143 |
| B2M | beta-2-microglobulin | 0.0329822 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0324317 |
| RPS12 | ribosomal protein S12 | 0.0320786 |
| MUC13 | mucin 13, cell surface associated | 0.0315347 |
| KRT8 | keratin 8, type II | 0.0313175 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310415 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0308552 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0306062 |
| EZR | ezrin | 0.0299142 |
| APP | amyloid beta (A4) precursor protein | 0.0298512 |
| PTMA | prothymosin, alpha | 0.0295284 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291132 |
| USP6NL | USP6 N-terminal like | 0.0289711 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0289334 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0278996 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0265148 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0254899 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0254544 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0253895 |
| RPS2 | ribosomal protein S2 | 0.0247901 |
| VEGFA | vascular endothelial growth factor A | 0.024281 |
| TPM3 | tropomyosin 3 | 0.0239301 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0233085 |
| EREG | epiregulin | 0.0231028 |
| YBX1 | Y box binding protein 1 | 0.0226529 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0224182 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.021547 |
| RPS3 | ribosomal protein S3 | 0.021253 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0212081 |
| FTL | ferritin, light polypeptide | 0.0206332 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.020588 |
| MCL1 | myeloid cell leukemia 1 | 0.0200727 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.019923 |
| MED13 | mediator complex subunit 13 | 0.019806 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0194565 |
| PLS1 | plastin 1 | 0.0194093 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0188615 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0186004 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0185644 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0185623 |
| RPS4X | ribosomal protein S4, X-linked | 0.0185218 |
| KIF5B | kinesin family member 5B | 0.0184907 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0183479 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0181612 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0181402 |
| MT2A | metallothionein 2A | 0.0175788 |
| RIGI | RNA sensor RIG-I | 0.0175555 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0175148 |
| CRY1 | cryptochrome circadian clock 1 | 0.0173486 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0172542 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0171411 |
| DUSP4 | dual specificity phosphatase 4 | 0.0170931 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.016898 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0167979 |
| GDA | guanine deaminase | 0.0166606 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0166355 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0165904 |
| ABHD2 | abhydrolase domain containing 2 | 0.0165844 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0165818 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0165312 |
| SFTPA2 | surfactant protein A2 | 0.0165232 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0165148 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0161209 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0160718 |
| WHRN | whirlin | 0.0159668 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.311017 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.202402 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.149899 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.126833 |
| VCL | vinculin | -0.114922 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.108219 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0824065 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0777172 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0744928 |
| FLNB | filamin B, beta | -0.0724493 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0712697 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0697118 |
| ONECUT3 | one cut homeobox 3 | -0.068614 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0665331 |
| GPHN | gephyrin | -0.0624585 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0611718 |
| TMSB10 | thymosin beta 10 | -0.0572306 |
| PRELID2 | PRELI domain containing 2 | -0.0571341 |
| NDRG1 | N-myc downstream regulated 1 | -0.0564198 |
| DENND1A | DENN/MADD domain containing 1A | -0.0563503 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0554663 |
| AGR2 | anterior gradient 2 | -0.0548951 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0546737 |
| ANXA2 | annexin A2 | -0.0530881 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0529053 |
| SBF2 | SET binding factor 2 | -0.050601 |
| LAMA4 | laminin, alpha 4 | -0.049124 |
| FHIT | fragile histidine triad | -0.0461098 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0456567 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0454276 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0453718 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0451633 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0446492 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0441389 |
| IER3 | immediate early response 3 | -0.0441284 |
| RPS24 | ribosomal protein S24 | -0.0430212 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0429333 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0426913 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0423985 |
| EHBP1 | EH domain binding protein 1 | -0.0416753 |
| SMYD3 | SET and MYND domain containing 3 | -0.04162 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0409161 |
| GOLGA4 | golgin A4 | -0.0407424 |
| DIAPH2 | diaphanous-related formin 2 | -0.0403756 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0399629 |
| RPS6 | ribosomal protein S6 | -0.0396744 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0390463 |
| ACTN4 | actinin, alpha 4 | -0.038921 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0385328 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.038279 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0379038 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0373238 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.036648 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0366212 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0366178 |
| RIN2 | Ras and Rab interactor 2 | -0.0365968 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0359721 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.035795 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0354468 |
| RAD51B | RAD51 paralog B | -0.0351144 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0350746 |
| CCND1 | cyclin D1 | -0.0349727 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0348536 |
| FERMT1 | fermitin family member 1 | -0.0348041 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.034752 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0346491 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0345936 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0345315 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0345222 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0344478 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0341308 |
| RRBP1 | ribosome binding protein 1 | -0.033913 |
| H1-0 | H1.0 linker histone | -0.0338475 |
| FRMD5 | FERM domain containing 5 | -0.0338022 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0337273 |
| EXOC4 | exocyst complex component 4 | -0.0333437 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0332119 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0329419 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.032857 |
| CANX | calnexin | -0.0328223 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0324668 |
| POF1B | premature ovarian failure, 1B | -0.03234 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0317392 |
| NFIA | nuclear factor I/A | -0.0316851 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.031509 |
| SETD5 | SET domain containing 5 | -0.0315013 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0312229 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0310108 |
| PALLD | palladin, cytoskeletal associated protein | -0.0308629 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0303057 |
| NBEAL1 | neurobeachin-like 1 | -0.0301069 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0296638 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0295273 |
| HMGA1 | high mobility group AT-hook 1 | -0.0293367 |
| MAP4 | microtubule-associated protein 4 | -0.0291842 |
| RPL35A | ribosomal protein L35a | -0.0291438 |
| RBM39 | RNA binding motif protein 39 | -0.0290573 |
| RNF217 | ring finger protein 217 | -0.0290101 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0286213 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0285546 |
