| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the ETC-206_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.203477 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.155957 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.153665 |
| SLTM | SAFB-like, transcription modulator | 0.132584 |
| ENO1 | enolase 1, (alpha) | 0.132207 |
| CPE | carboxypeptidase E | 0.109171 |
| STC1 | stanniocalcin 1 | 0.0997587 |
| MCL1 | myeloid cell leukemia 1 | 0.0984641 |
| LDHA | lactate dehydrogenase A | 0.0980122 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0907426 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0834795 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0785374 |
| PKM | pyruvate kinase, muscle | 0.0770497 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0756487 |
| GRAMD1B | GRAM domain containing 1B | 0.0746683 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0740159 |
| TXNRD1 | thioredoxin reductase 1 | 0.0720561 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0713471 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0704068 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0696875 |
| LMO7 | LIM domain 7 | 0.0688333 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0682896 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0677564 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0642737 |
| ACTG1 | actin gamma 1 | 0.0638254 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0618363 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0618155 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0566702 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0563215 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0562897 |
| PCBP2 | poly(rC) binding protein 2 | 0.0534146 |
| RPS3 | ribosomal protein S3 | 0.0526456 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0522506 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0520513 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0508569 |
| CES1 | carboxylesterase 1 | 0.0505516 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0504329 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0497173 |
| ADAR | adenosine deaminase, RNA-specific | 0.0494802 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0492385 |
| AREG | amphiregulin | 0.0487527 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0478946 |
| MT2A | metallothionein 2A | 0.0473784 |
| EFNA5 | ephrin-A5 | 0.0468695 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0455557 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0452806 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0451297 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.045044 |
| POTEF | POTE ankyrin domain family, member F | 0.0449396 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0434209 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0423648 |
| RNF213 | ring finger protein 213 | 0.041042 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0406374 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0391384 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0387266 |
| DSPP | dentin sialophosphoprotein | 0.0380895 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0380583 |
| AHNAK | AHNAK nucleoprotein | 0.0370883 |
| MYOF | myoferlin | 0.0369647 |
| SP100 | SP100 nuclear antigen | 0.0364055 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0355278 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0348212 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0347907 |
| RPL3 | ribosomal protein L3 | 0.0342629 |
| BMP6 | bone morphogenetic protein 6 | 0.0340297 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0340292 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0334008 |
| SIK3 | SIK family kinase 3 | 0.0333677 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0333095 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0313902 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0313734 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0311789 |
| S100A10 | S100 calcium binding protein A10 | 0.0310764 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0310336 |
| IRS2 | insulin receptor substrate 2 | 0.0305039 |
| HOMER1 | homer scaffolding protein 1 | 0.030416 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0302621 |
| TPM3 | tropomyosin 3 | 0.0302372 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0302311 |
| AGO2 | argonaute RISC catalytic component 2 | 0.030145 |
| CAV2 | caveolin 2 | 0.0301397 |
| B2M | beta-2-microglobulin | 0.0296897 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.029293 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0285934 |
| CSNK1E | casein kinase 1, epsilon | 0.0285106 |
| MX1 | MX dynamin-like GTPase 1 | 0.0284733 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0282553 |
| RPL4 | ribosomal protein L4 | 0.0281546 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0280653 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0273032 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0270987 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0270733 |
| SQOR | sulfide quinone oxidoreductase | 0.0266302 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0265463 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0261426 |
| APP | amyloid beta (A4) precursor protein | 0.0260052 |
| RPS4X | ribosomal protein S4, X-linked | 0.0258991 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0254914 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0253797 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0249808 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | -0.144686 |
| NDRG1 | N-myc downstream regulated 1 | -0.111414 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0843601 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0789234 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0679104 |
| NABP1 | nucleic acid binding protein 1 | -0.0538708 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.050517 |
| H1-0 | H1.0 linker histone | -0.0481769 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0449826 |
| ASPH | aspartate beta-hydroxylase | -0.0442453 |
| TMEM165 | transmembrane protein 165 | -0.0367013 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0359465 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0356821 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0346761 |
| INTS6 | integrator complex subunit 6 | -0.034314 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0340221 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0323056 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0322678 |
| HDLBP | high density lipoprotein binding protein | -0.0304366 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0293632 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0264738 |
| EGR1 | early growth response 1 | -0.0260012 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0252467 |
| OSMR | oncostatin M receptor | -0.0250654 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0250114 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0243633 |
| NCOA2 | nuclear receptor coactivator 2 | -0.0235339 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0234301 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0228862 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0228542 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0226063 |
| GM2A | GM2 ganglioside activator | -0.0224497 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0221937 |
| EHBP1 | EH domain binding protein 1 | -0.02216 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0219166 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0216846 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.020849 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0205132 |
| HMGA1 | high mobility group AT-hook 1 | -0.0205074 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0201908 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0200766 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0198269 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0196887 |
| FNIP1 | folliculin interacting protein 1 | -0.01905 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0189978 |
| NEBL | nebulette | -0.0189376 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0189316 |
| RIN2 | Ras and Rab interactor 2 | -0.0184989 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0184475 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0183372 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | -0.0182114 |
| SEC24D | SEC24 family member D | -0.0182022 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0181856 |
| WASF2 | WAS protein family, member 2 | -0.0173995 |
| BBX | bobby sox homolog (Drosophila) | -0.0173779 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0173694 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0173685 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0171507 |
| SRP54 | signal recognition particle 54kDa | -0.0170129 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0167855 |
| NDE1 | nudE neurodevelopment protein 1 | -0.0164785 |
| PCED1B | PC-esterase domain containing 1B | -0.0164233 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0164132 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0164119 |
| FLNB | filamin B, beta | -0.0163172 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0162864 |
| SQSTM1 | sequestosome 1 | -0.016224 |
| SUMF1 | sulfatase modifying factor 1 | -0.016152 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0161444 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0155964 |
| AGR2 | anterior gradient 2 | -0.015541 |
| FOXO3 | forkhead box O3 | -0.0154872 |
| UBAC2 | UBA domain containing 2 | -0.0154688 |
| PRKCA | protein kinase C, alpha | -0.0154291 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0153772 |
| RASA2 | RAS p21 protein activator 2 | -0.0151825 |
| CERT1 | ceramide transporter 1 | -0.0151757 |
| CCNL1 | cyclin L1 | -0.0150719 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0150264 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0149813 |
| TRAPPC12 | trafficking protein particle complex 12 | -0.0149313 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.014928 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0149252 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0149096 |
| OGA | O-GlcNAcase | -0.0148429 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0148363 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0147915 |
| HM13 | histocompatibility (minor) 13 | -0.0147369 |
| WDR45B | WD repeat domain 45B | -0.0146978 |
| TXNDC11 | thioredoxin domain containing 11 | -0.0146413 |
| UPP1 | uridine phosphorylase 1 | -0.0146096 |
| FRYL | FRY-like | -0.014544 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0144843 |
| MAP4 | microtubule-associated protein 4 | -0.0144671 |
| GOLGA3 | golgin A3 | -0.0144421 |
| WDR49 | WD repeat domain 49 | -0.0144339 |
| SBF2 | SET binding factor 2 | -0.0143551 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0141992 |
| FUS | FUS RNA binding protein | -0.01411 |
| NIBAN1 | niban apoptosis regulator 1 | -0.014094 |
