| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217448 |
| VIM | vimentin | 0.169255 |
| CD44 | CD44 molecule (Indian blood group) | 0.129086 |
| ENO1 | enolase 1, (alpha) | 0.117989 |
| PCBP2 | poly(rC) binding protein 2 | 0.103717 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.100067 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0969951 |
| LOX | lysyl oxidase | 0.096982 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0957889 |
| LDHA | lactate dehydrogenase A | 0.078258 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0770233 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0743556 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0738019 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0728311 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0669744 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0650935 |
| ANGPTL4 | angiopoietin-like 4 | 0.0641722 |
| B2M | beta-2-microglobulin | 0.0636032 |
| PLIN2 | perilipin 2 | 0.0635818 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0625205 |
| IFI44L | interferon-induced protein 44-like | 0.0616554 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0611716 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.06095 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0606914 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0606335 |
| AHNAK | AHNAK nucleoprotein | 0.0604878 |
| NTN4 | netrin 4 | 0.058299 |
| SMAD3 | SMAD family member 3 | 0.0571514 |
| POTEF | POTE ankyrin domain family, member F | 0.0524377 |
| MYO10 | myosin X | 0.0519795 |
| ECE1 | endothelin converting enzyme 1 | 0.0511265 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0487428 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0482221 |
| FAM20C | family with sequence similarity 20, member C | 0.0481244 |
| TGM2 | transglutaminase 2 | 0.0481215 |
| PKM | pyruvate kinase, muscle | 0.0443501 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0435198 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0431921 |
| RPS12 | ribosomal protein S12 | 0.0428837 |
| VEGFA | vascular endothelial growth factor A | 0.0427833 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.042338 |
| LOXL2 | lysyl oxidase-like 2 | 0.0418897 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0405364 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.040515 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0397453 |
| RPL4 | ribosomal protein L4 | 0.03926 |
| MCL1 | myeloid cell leukemia 1 | 0.038931 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0378746 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0371515 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0362615 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0358389 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0354569 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0352826 |
| RPL3 | ribosomal protein L3 | 0.0352671 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0352082 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0351968 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0349384 |
| KSR1 | kinase suppressor of ras 1 | 0.0342724 |
| AADAC | arylacetamide deacetylase | 0.0341939 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0337896 |
| STK38L | serine/threonine kinase 38 like | 0.0337466 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0333343 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0331006 |
| FAM107B | family with sequence similarity 107, member B | 0.0326492 |
| TMSB4X | thymosin beta 4, X-linked | 0.0319944 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0312206 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.031107 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0310114 |
| APP | amyloid beta (A4) precursor protein | 0.0308709 |
| SFTPA2 | surfactant protein A2 | 0.0306266 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0304955 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0300401 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0299424 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0298321 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0297116 |
| NRP1 | neuropilin 1 | 0.0296603 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0296293 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0295239 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0295124 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0293099 |
| THBS1 | thrombospondin 1 | 0.0290648 |
| EREG | epiregulin | 0.0286389 |
| MT2A | metallothionein 2A | 0.0283244 |
| NAV2 | neuron navigator 2 | 0.0280573 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0276365 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0276095 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.027513 |
| HAS2 | hyaluronan synthase 2 | 0.0274759 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0272788 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.026623 |
| ADD3 | adducin 3 (gamma) | 0.026275 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0261954 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0261695 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0258483 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0258426 |
| RPS3 | ribosomal protein S3 | 0.0254959 |
| KYNU | kynureninase | 0.0254772 |
| CA12 | carbonic anhydrase XII | 0.0254047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253241 |
| IL1B | interleukin 1, beta | 0.0253012 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.169334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.165017 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.129974 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.124766 |
| CDH13 | cadherin 13 | -0.109035 |
| RBM39 | RNA binding motif protein 39 | -0.106149 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.101417 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0775122 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0739701 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0736915 |
| GPC6 | glypican 6 | -0.0673029 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0672226 |
| GOLGA4 | golgin A4 | -0.0620895 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0608066 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0586651 |
| PRELID2 | PRELI domain containing 2 | -0.0586602 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0581195 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0579545 |
| MEF2A | myocyte enhancer factor 2A | -0.0557996 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0552835 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0542846 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0538436 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0532266 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0520448 |
| SPAG9 | sperm associated antigen 9 | -0.0486808 |
| OGA | O-GlcNAcase | -0.0474061 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0471189 |
| PARD3 | par-3 family cell polarity regulator | -0.0464791 |
| USP34 | ubiquitin specific peptidase 34 | -0.0463435 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0450745 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0447276 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0435994 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0433202 |
| IER3 | immediate early response 3 | -0.0431967 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0428285 |
| FAM13A | family with sequence similarity 13, member A | -0.0395813 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0391783 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0387964 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0387953 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0378996 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0378725 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0375174 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0371806 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0371296 |
| ANKRD11 | ankyrin repeat domain 11 | -0.037113 |
| MORF4L2 | mortality factor 4 like 2 | -0.0361184 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.035422 |
| TMEM263 | transmembrane protein 263 | -0.0354118 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0346639 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0344232 |
| FN1 | fibronectin 1 | -0.0343611 |
| MECOM | MDS1 and EVI1 complex locus | -0.0339394 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0335757 |
| ZNF804A | zinc finger protein 804A | -0.0334159 |
| SBF2 | SET binding factor 2 | -0.0331814 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0330411 |
| CDK14 | cyclin-dependent kinase 14 | -0.0330365 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0327908 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0327371 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0319805 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0318385 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0317327 |
| GNAS | GNAS complex locus | -0.0316821 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0316706 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0313152 |
| HDLBP | high density lipoprotein binding protein | -0.0312237 |
| NF1 | neurofibromin 1 | -0.031074 |
| CFAP20DC | CFAP20 domain containing | -0.0309963 |
| SETD5 | SET domain containing 5 | -0.0309774 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0309513 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0308607 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0306144 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0305452 |
| COG5 | component of oligomeric golgi complex 5 | -0.0303833 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0299443 |
| USP3 | ubiquitin specific peptidase 3 | -0.0296598 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0291911 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | -0.0281245 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.0278464 |
| HELZ | helicase with zinc finger | -0.0278395 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0278378 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027669 |
| ARF4 | ADP-ribosylation factor 4 | -0.0275912 |
| DENND4A | DENN/MADD domain containing 4A | -0.0271719 |
| JMJD1C | jumonji domain containing 1C | -0.0269725 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.02696 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0268791 |
| MTSS1 | metastasis suppressor 1 | -0.0268141 |
| MAP4 | microtubule-associated protein 4 | -0.026701 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0265424 |
| WDR45B | WD repeat domain 45B | -0.0263196 |
| SEC24D | SEC24 family member D | -0.0261411 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0261005 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0259994 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0258914 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0255154 |
| OXSR1 | oxidative stress responsive 1 | -0.0253559 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0253178 |
| OSMR | oncostatin M receptor | -0.0252251 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0251942 |
