| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.195343 |
| POTEF | POTE ankyrin domain family, member F | 0.158322 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.144125 |
| ACTG1 | actin gamma 1 | 0.107082 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.10584 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0941541 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0854998 |
| NAV2 | neuron navigator 2 | 0.0809312 |
| AHNAK | AHNAK nucleoprotein | 0.0798451 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.074347 |
| EFNA5 | ephrin-A5 | 0.0717328 |
| ENO1 | enolase 1, (alpha) | 0.0697193 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0671769 |
| ASPH | aspartate beta-hydroxylase | 0.0613829 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0541173 |
| RUNX1 | runt-related transcription factor 1 | 0.0494953 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0483425 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0475653 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0466787 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0458572 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0456172 |
| SDC4 | syndecan 4 | 0.0448905 |
| KIAA1217 | KIAA1217 | 0.0398368 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0397143 |
| ARHGAP20 | Rho GTPase activating protein 20 | 0.0396635 |
| SGMS2 | sphingomyelin synthase 2 | 0.0393844 |
| SVIL | supervillin | 0.0386893 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0385325 |
| ATXN1 | ataxin 1 | 0.0362001 |
| FHIT | fragile histidine triad | 0.0359477 |
| SMAD3 | SMAD family member 3 | 0.0355784 |
| INTS6 | integrator complex subunit 6 | 0.0341327 |
| LDHA | lactate dehydrogenase A | 0.0337681 |
| VGLL3 | vestigial-like family member 3 | 0.0334994 |
| EGFR | epidermal growth factor receptor | 0.0333865 |
| PALLD | palladin, cytoskeletal associated protein | 0.0332009 |
| MCL1 | myeloid cell leukemia 1 | 0.0329139 |
| DSPP | dentin sialophosphoprotein | 0.0328258 |
| HDAC9 | histone deacetylase 9 | 0.0327615 |
| ANO6 | anoctamin 6 | 0.0327403 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0323731 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0319889 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0319086 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0313978 |
| LAMC2 | laminin, gamma 2 | 0.0306082 |
| NTN4 | netrin 4 | 0.0305464 |
| CENPF | centromere protein F, 350/400kDa | 0.0301851 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.029857 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0296889 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0290245 |
| BRD2 | bromodomain containing 2 | 0.0279708 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0275611 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0275437 |
| ADAR | adenosine deaminase, RNA-specific | 0.0272155 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0265689 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0265352 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0264928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0260957 |
| MYOF | myoferlin | 0.0259582 |
| MSN | moesin | 0.0252063 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0248896 |
| MYO5B | myosin VB | 0.0244758 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0244026 |
| DOCK5 | dedicator of cytokinesis 5 | 0.02401 |
| IFI44L | interferon-induced protein 44-like | 0.0235027 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0233736 |
| RPL3 | ribosomal protein L3 | 0.0232976 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0232189 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.0231149 |
| DIAPH1 | diaphanous-related formin 1 | 0.0228444 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0228415 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0226081 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0225453 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0225202 |
| VCL | vinculin | 0.022326 |
| TJP1 | tight junction protein 1 | 0.0221794 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0221753 |
| NABP1 | nucleic acid binding protein 1 | 0.0220494 |
| SEPTIN9 | septin 9 | 0.0217024 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0212195 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0211928 |
| OCLN | occludin | 0.0208422 |
| EGR1 | early growth response 1 | 0.0206617 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0205827 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0205719 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0204401 |
| MT2A | metallothionein 2A | 0.0201012 |
| CD44 | CD44 molecule (Indian blood group) | 0.0200947 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0200696 |
| GRAMD2B | GRAM domain containing 2B | 0.0200515 |
| MKI67 | marker of proliferation Ki-67 | 0.0199938 |
| AREG | amphiregulin | 0.0199914 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.019964 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0198219 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0196816 |
| CPM | carboxypeptidase M | 0.0195854 |
| ARRDC3 | arrestin domain containing 3 | 0.0195058 |
| GLCCI1 | glucocorticoid induced 1 | 0.0194957 |
| PRKCA | protein kinase C, alpha | 0.0191229 |
| SMYD3 | SET and MYND domain containing 3 | 0.0189781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.158304 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.153654 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.150147 |
| FTL | ferritin, light polypeptide | -0.143984 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0884152 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0855843 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0836923 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0771808 |
| NDRG1 | N-myc downstream regulated 1 | -0.0745124 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0739022 |
| TPM4 | tropomyosin 4 | -0.0718818 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0626385 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0619977 |
| FN1 | fibronectin 1 | -0.0616885 |
| TMSB4X | thymosin beta 4, X-linked | -0.0598016 |
| GNAS | GNAS complex locus | -0.059285 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0566906 |
| RAB1A | RAB1A, member RAS oncogene family | -0.05658 |
| GOLGA4 | golgin A4 | -0.0563622 |
| CANX | calnexin | -0.0557722 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0555296 |
| RPL35A | ribosomal protein L35a | -0.0552588 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0548307 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0548187 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0538494 |
| FBXO32 | F-box protein 32 | -0.0536177 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0524608 |
| RPL34 | ribosomal protein L34 | -0.0512101 |
| SLMAP | sarcolemma associated protein | -0.0508662 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0506775 |
| CD2AP | CD2-associated protein | -0.0506008 |
| RPS6 | ribosomal protein S6 | -0.0499411 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0473616 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.046833 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0468016 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0467803 |
| CSTB | cystatin B (stefin B) | -0.0466879 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0465847 |
| RBM39 | RNA binding motif protein 39 | -0.0457319 |
| CCND1 | cyclin D1 | -0.044137 |
| TOP1 | topoisomerase (DNA) I | -0.0435442 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0435355 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0433234 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0405615 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0405603 |
| LAMB3 | laminin, beta 3 | -0.0400707 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0400395 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0399213 |
| RBM25 | RNA binding motif protein 25 | -0.0398284 |
| LMAN1 | lectin, mannose-binding, 1 | -0.038359 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0383536 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0383334 |
| RTN4 | reticulon 4 | -0.0381727 |
| HLA-A | major histocompatibility complex, class I, A | -0.0378251 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0374644 |
| TMEM165 | transmembrane protein 165 | -0.0371144 |
| OGA | O-GlcNAcase | -0.0370541 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0357092 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0354586 |
| S100A6 | S100 calcium binding protein A6 | -0.0353177 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0352146 |
| USP3 | ubiquitin specific peptidase 3 | -0.0351502 |
| RPS8 | ribosomal protein S8 | -0.0350153 |
| TMEM123 | transmembrane protein 123 | -0.0350039 |
| MSI2 | musashi RNA-binding protein 2 | -0.0344327 |
| RPL37A | ribosomal protein L37a | -0.0344281 |
| KLHL24 | kelch-like family member 24 | -0.0337562 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0334213 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0331781 |
| RPLP1 | ribosomal protein, large, P1 | -0.0331332 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0330663 |
| RIOK3 | RIO kinase 3 | -0.0329413 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0328063 |
| RPL9 | ribosomal protein L9 | -0.0327701 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.03253 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0324667 |
| MXD1 | MAX dimerization protein 1 | -0.032297 |
| H3-3B | H3.3 histone B | -0.0318414 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0313984 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0313234 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.031209 |
| CERT1 | ceramide transporter 1 | -0.0308882 |
| CEP350 | centrosomal protein 350kDa | -0.0307155 |
| TFG | TRK-fused gene | -0.030714 |
| SPAG9 | sperm associated antigen 9 | -0.0307071 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0306885 |
| RLF | rearranged L-myc fusion | -0.0306065 |
| TMSB10 | thymosin beta 10 | -0.0304482 |
| HLA-E | major histocompatibility complex, class I, E | -0.0303213 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0302829 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.03017 |
| TPR | translocated promoter region, nuclear basket protein | -0.0301054 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0297856 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0296962 |
| RPS27A | ribosomal protein S27a | -0.0296674 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0296235 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0291733 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0291119 |
| YY1 | YY1 transcription factor | -0.0290626 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0289408 |
