| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.20611 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.178799 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.171777 |
| MYOF | myoferlin | 0.138082 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.134853 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.130629 |
| AHNAK | AHNAK nucleoprotein | 0.125601 |
| DST | dystonin | 0.12472 |
| ENO1 | enolase 1, (alpha) | 0.122893 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.115198 |
| EFNA5 | ephrin-A5 | 0.107473 |
| FMNL2 | formin-like 2 | 0.103601 |
| GOLGB1 | golgin B1 | 0.0932462 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0929982 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0917299 |
| ASPH | aspartate beta-hydroxylase | 0.0916217 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0910628 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0910301 |
| RPLP1 | ribosomal protein, large, P1 | 0.0899407 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0893002 |
| ACTG1 | actin gamma 1 | 0.086787 |
| TMSB10 | thymosin beta 10 | 0.0841275 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0840458 |
| EZR | ezrin | 0.0839698 |
| ATXN1 | ataxin 1 | 0.0818844 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0811796 |
| MCL1 | myeloid cell leukemia 1 | 0.0783762 |
| MED13L | mediator complex subunit 13-like | 0.0779727 |
| LAMB3 | laminin, beta 3 | 0.0776956 |
| LMO7 | LIM domain 7 | 0.0751657 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0740134 |
| PDE10A | phosphodiesterase 10A | 0.0719595 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0718312 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0692592 |
| USP34 | ubiquitin specific peptidase 34 | 0.0687912 |
| RPL37A | ribosomal protein L37a | 0.0682302 |
| POTEF | POTE ankyrin domain family, member F | 0.0672876 |
| RPS3 | ribosomal protein S3 | 0.0670278 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0651066 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0643257 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0595194 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0558753 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0554946 |
| RBM39 | RNA binding motif protein 39 | 0.051053 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0508153 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0504059 |
| CD44 | CD44 molecule (Indian blood group) | 0.0500297 |
| JMJD1C | jumonji domain containing 1C | 0.0461016 |
| RPS8 | ribosomal protein S8 | 0.044634 |
| TPM4 | tropomyosin 4 | 0.0440235 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0435285 |
| RBM25 | RNA binding motif protein 25 | 0.0418454 |
| PGK1 | phosphoglycerate kinase 1 | 0.0413744 |
| RPL37 | ribosomal protein L37 | 0.0395613 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.039262 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0385632 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0380485 |
| RPL26 | ribosomal protein L26 | 0.0369276 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0365611 |
| INTS6 | integrator complex subunit 6 | 0.0335601 |
| RPL19 | ribosomal protein L19 | 0.029983 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0297414 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0297354 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0296391 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0296022 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0294668 |
| RPS6 | ribosomal protein S6 | 0.0294027 |
| PTK2 | protein tyrosine kinase 2 | 0.0291851 |
| LDHA | lactate dehydrogenase A | 0.0286995 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.028252 |
| COG5 | component of oligomeric golgi complex 5 | 0.0254652 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0253322 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0239082 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0238678 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0222483 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.021727 |
| FN1 | fibronectin 1 | 0.021628 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215554 |
| LAMC2 | laminin, gamma 2 | 0.0200265 |
| TENM3 | teneurin transmembrane protein 3 | 0.0177418 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0171302 |
| VIM | vimentin | 0.0170585 |
| MYO1E | myosin IE | 0.0169316 |
| ADIPOR2 | adiponectin receptor 2 | 0.0151208 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0136488 |
| SBF2 | SET binding factor 2 | 0.0135371 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0134281 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0130078 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.012739 |
| FTL | ferritin, light polypeptide | 0.0124575 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0120963 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0116719 |
| FLNB | filamin B, beta | 0.01158 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0114652 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0111281 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0100834 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.00968438 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00926092 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0090102 |
| MT2A | metallothionein 2A | 0.00820346 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.188142 |
| EGFR | epidermal growth factor receptor | -0.115382 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0949017 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0906862 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0905674 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0840741 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0807674 |
| TCF12 | transcription factor 12 | -0.0804358 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0802967 |
| APP | amyloid beta (A4) precursor protein | -0.0802491 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.0799615 |
| PRKD3 | protein kinase D3 | -0.0790415 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0786617 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0774528 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0754367 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0749771 |
| NBEAL1 | neurobeachin-like 1 | -0.0734005 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0716121 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0709274 |
| SETD5 | SET domain containing 5 | -0.0693388 |
| RIGI | RNA sensor RIG-I | -0.0669178 |
| BBX | bobby sox homolog (Drosophila) | -0.0644256 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0627618 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0625845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0611955 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0606427 |
| RORA | RAR-related orphan receptor A | -0.0606121 |
| AOPEP | aminopeptidase O (putative) | -0.0603987 |
| CANX | calnexin | -0.0580286 |
| PKM | pyruvate kinase, muscle | -0.0580246 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.057578 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0550785 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0542412 |
| STC1 | stanniocalcin 1 | -0.0540547 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0529237 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0517153 |
| MAP4 | microtubule-associated protein 4 | -0.0514395 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0505885 |
| SMYD3 | SET and MYND domain containing 3 | -0.0494147 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0489085 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0483298 |
| NFIA | nuclear factor I/A | -0.0482868 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.047972 |
| CDH13 | cadherin 13 | -0.0474619 |
| SLTM | SAFB-like, transcription modulator | -0.0469835 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0464427 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0452682 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.045199 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0436097 |
| CTBP2 | C-terminal binding protein 2 | -0.0430421 |
| ZNF292 | zinc finger protein 292 | -0.0418788 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.041529 |
| TOP1 | topoisomerase (DNA) I | -0.0405098 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0396165 |
| IGF2 | insulin-like growth factor 2 | -0.0386147 |
| CDC73 | cell division cycle 73 | -0.0377246 |
| LOXL2 | lysyl oxidase-like 2 | -0.037698 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0371109 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0360195 |
| CD2AP | CD2-associated protein | -0.0359739 |
| RAB10 | RAB10, member RAS oncogene family | -0.0358135 |
| RPL35A | ribosomal protein L35a | -0.0355563 |
| RPL12 | ribosomal protein L12 | -0.0346614 |
| PRKCA | protein kinase C, alpha | -0.0338778 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0338549 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0337377 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0336866 |
| COL1A1 | collagen, type I, alpha 1 | -0.0332615 |
| COPA | coatomer protein complex, subunit alpha | -0.0332302 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0328865 |
| RPS21 | ribosomal protein S21 | -0.0316976 |
| RNF213 | ring finger protein 213 | -0.0316477 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0314182 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.030974 |
| MSI2 | musashi RNA-binding protein 2 | -0.030954 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0304097 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0303246 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0300197 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.030007 |
| NF1 | neurofibromin 1 | -0.0299947 |
| VMP1 | vacuole membrane protein 1 | -0.0298597 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0295926 |
| SPAG9 | sperm associated antigen 9 | -0.02941 |
| FRMD4A | FERM domain containing 4A | -0.0274359 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0272518 |
| FNBP1 | formin binding protein 1 | -0.0272475 |
| PARD3 | par-3 family cell polarity regulator | -0.0255932 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0254851 |
| TXNRD1 | thioredoxin reductase 1 | -0.0250745 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0248802 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0248796 |
| CERS6 | ceramide synthase 6 | -0.0244023 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0237439 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.023521 |
| HMGA2 | high mobility group AT-hook 2 | -0.0233712 |
| SQSTM1 | sequestosome 1 | -0.023008 |
| TLK1 | tousled-like kinase 1 | -0.022532 |
| GOLGA4 | golgin A4 | -0.021962 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0206343 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0189827 |
