| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NTM | neurotrimin | 0.0969096 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0584097 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0485799 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0430314 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.041494 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0396433 |
| THBS1 | thrombospondin 1 | 0.0355929 |
| RPL3 | ribosomal protein L3 | 0.0345597 |
| PCDH18 | protocadherin 18 | 0.0344714 |
| PEG10 | paternally expressed 10 | 0.0338752 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0279993 |
| PCBP2 | poly(rC) binding protein 2 | 0.0279563 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0277036 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.0274411 |
| COL5A2 | collagen, type V, alpha 2 | 0.0274274 |
| HDAC9 | histone deacetylase 9 | 0.0268482 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0256876 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0252208 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0245902 |
| RPL4 | ribosomal protein L4 | 0.0243157 |
| ENO1 | enolase 1, (alpha) | 0.0242494 |
| BRD2 | bromodomain containing 2 | 0.023904 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0230729 |
| GPHN | gephyrin | 0.0229199 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0226535 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0223382 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0215669 |
| CENPF | centromere protein F, 350/400kDa | 0.0208347 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0203729 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0203195 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0202111 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0197514 |
| APP | amyloid beta (A4) precursor protein | 0.0194815 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.019339 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0192483 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0192106 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0191701 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0191048 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0190923 |
| MEF2C | myocyte enhancer factor 2C | 0.0189968 |
| CEP192 | centrosomal protein 192kDa | 0.0187964 |
| STAG2 | stromal antigen 2 | 0.0187442 |
| APMAP | adipocyte plasma membrane associated protein | 0.018658 |
| FOXG1 | forkhead box G1 | 0.0186389 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0183195 |
| NFIB | nuclear factor I/B | 0.0182821 |
| CALR | calreticulin | 0.0182549 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0180633 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0175661 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0175011 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0174679 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0172584 |
| PKP4 | plakophilin 4 | 0.0170755 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0170185 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0168248 |
| ATL2 | atlastin GTPase 2 | 0.0168097 |
| ITGAV | integrin, alpha V | 0.0167394 |
| HYOU1 | hypoxia up-regulated 1 | 0.016643 |
| TTC21B | tetratricopeptide repeat domain 21B | 0.0165051 |
| NONO | non-POU domain containing, octamer-binding | 0.0165025 |
| EMC1 | ER membrane protein complex subunit 1 | 0.0163349 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0163302 |
| CDC14A | cell division cycle 14A | 0.0162985 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.0161988 |
| CFL2 | cofilin 2 (muscle) | 0.0161531 |
| HTATSF1 | HIV-1 Tat specific factor 1 | 0.0161464 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0161437 |
| DIXDC1 | DIX domain containing 1 | 0.016071 |
| PIKFYVE | phosphoinositide kinase, FYVE finger containing | 0.0158595 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0157968 |
| CDCA7L | cell division cycle associated 7-like | 0.0157028 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0156866 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0156804 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0156688 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.0155872 |
| NCKAP1 | NCK-associated protein 1 | 0.0155845 |
| TGOLN2 | trans-golgi network protein 2 | 0.0155827 |
| FAT1 | FAT atypical cadherin 1 | 0.0154588 |
| STRN | striatin, calmodulin binding protein | 0.0154025 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 | 0.0152678 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0152419 |
| SPAG5 | sperm associated antigen 5 | 0.0152047 |
| DICER1 | dicer 1, ribonuclease type III | 0.0151704 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.015091 |
| PCDH7 | protocadherin 7 | 0.0149764 |
| ADD3 | adducin 3 (gamma) | 0.0149413 |
| RNF111 | ring finger protein 111 | 0.0149115 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | 0.0148635 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 | 0.0148108 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0147988 |
| NELL2 | NEL-like 2 (chicken) | 0.0147774 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.0147728 |
| NPTN | neuroplastin | 0.0147536 |
| CSNK1D | casein kinase 1, delta | 0.0146424 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.0146309 |
| CASP8AP2 | caspase 8 associated protein 2 | 0.0144854 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0144613 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0144596 |
| RGS5 | regulator of G-protein signaling 5 | 0.0144543 |
| STX16 | syntaxin 16 | 0.0144 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.242425 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.155568 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.145288 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.124035 |
| TMSB10 | thymosin beta 10 | -0.121044 |
| RPS6 | ribosomal protein S6 | -0.118296 |
| PTMA | prothymosin, alpha | -0.113353 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.106846 |
| GPC3 | glypican 3 | -0.0855202 |
| RPS16 | ribosomal protein S16 | -0.0854711 |
| GNAS | GNAS complex locus | -0.0834251 |
| EMP1 | epithelial membrane protein 1 | -0.0795241 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0718331 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0701409 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0681045 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0675788 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0663489 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0647299 |
| RPS8 | ribosomal protein S8 | -0.0646745 |
| H1-0 | H1.0 linker histone | -0.0642896 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0639571 |
| SPAG9 | sperm associated antigen 9 | -0.0613281 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0612884 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0606326 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0582738 |
| RPL35A | ribosomal protein L35a | -0.0581955 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0580721 |
| PHIP | pleckstrin homology domain interacting protein | -0.056772 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0553672 |
| RPL19 | ribosomal protein L19 | -0.0547323 |
| PCDH9 | protocadherin 9 | -0.0544602 |
| PGK1 | phosphoglycerate kinase 1 | -0.0536213 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0529619 |
| RPLP1 | ribosomal protein, large, P1 | -0.052274 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0521306 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0519756 |
| MAP4 | microtubule-associated protein 4 | -0.0519106 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0511275 |
| RPS21 | ribosomal protein S21 | -0.0507002 |
| HMGB1 | high mobility group box 1 | -0.049847 |
| HSPB1 | heat shock 27kDa protein 1 | -0.049824 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0484355 |
| HMGA1 | high mobility group AT-hook 1 | -0.0481421 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0477271 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0474013 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.047385 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0469363 |
| S100A10 | S100 calcium binding protein A10 | -0.0456616 |
| FN1 | fibronectin 1 | -0.0446897 |
| RPL31 | ribosomal protein L31 | -0.0442024 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0437981 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0435625 |
| ZNF292 | zinc finger protein 292 | -0.0433472 |
| DMD | dystrophin | -0.0433161 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0425497 |
| PFN1 | profilin 1 | -0.0423922 |
| SETD5 | SET domain containing 5 | -0.0420203 |
| B2M | beta-2-microglobulin | -0.0409348 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0409344 |
| MPG | N-methylpurine-DNA glycosylase | -0.0399265 |
| ANXA2 | annexin A2 | -0.0397241 |
| CADM2 | cell adhesion molecule 2 | -0.0397228 |
| RPS13 | ribosomal protein S13 | -0.0397174 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0396203 |
| RAI1 | retinoic acid induced 1 | -0.039451 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0393962 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0393302 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.038863 |
| RPS19 | ribosomal protein S19 | -0.0382431 |
| RTN4 | reticulon 4 | -0.0377333 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.037552 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0374283 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0373874 |
| RPS24 | ribosomal protein S24 | -0.0372424 |
| RACK1 | receptor for activated C kinase 1 | -0.0371126 |
| RPL34 | ribosomal protein L34 | -0.0366401 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0365314 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0363668 |
| RYBP | RING1 and YY1 binding protein | -0.0351392 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0349403 |
| FTL | ferritin, light polypeptide | -0.0345784 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0343786 |
| RAD51B | RAD51 paralog B | -0.0343097 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0342275 |
| UBC | ubiquitin C | -0.0340699 |
| RPS10 | ribosomal protein S10 | -0.0340504 |
| SRP54 | signal recognition particle 54kDa | -0.0337847 |
| PTK2 | protein tyrosine kinase 2 | -0.0337508 |
| PDS5A | PDS5 cohesin associated factor A | -0.0336263 |
| RPS15 | ribosomal protein S15 | -0.0335867 |
| RASAL2 | RAS protein activator like 2 | -0.0333407 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0333281 |
| USP53 | ubiquitin specific peptidase 53 | -0.0332873 |
| RPL37A | ribosomal protein L37a | -0.0332561 |
| COL3A1 | collagen, type III, alpha 1 | -0.0332009 |
| ZNF217 | zinc finger protein 217 | -0.0331306 |
| RPL11 | ribosomal protein L11 | -0.0329081 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0326533 |
| SRP72 | signal recognition particle 72kDa | -0.0323514 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0322843 |
