| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.14621 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0828438 |
| EGFR | epidermal growth factor receptor | 0.0759577 |
| AHNAK | AHNAK nucleoprotein | 0.066792 |
| BMP10 | bone morphogenetic protein 10 | 0.0518245 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0430658 |
| PDGFC | platelet derived growth factor C | 0.0362731 |
| ANXA1 | annexin A1 | 0.0349064 |
| FER1L6 | fer-1-like family member 6 | 0.0343944 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0330888 |
| ZNF608 | zinc finger protein 608 | 0.031565 |
| MYO5C | myosin VC | 0.0310532 |
| HDAC9 | histone deacetylase 9 | 0.0302079 |
| RPL3 | ribosomal protein L3 | 0.0287901 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0267793 |
| RPL4 | ribosomal protein L4 | 0.0250342 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0245336 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239314 |
| GLI3 | GLI family zinc finger 3 | 0.0239246 |
| PRELID2 | PRELI domain containing 2 | 0.0235222 |
| DUSP4 | dual specificity phosphatase 4 | 0.0233745 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0225477 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0224689 |
| EZR | ezrin | 0.0215818 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0209818 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0206019 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0195314 |
| GLI2 | GLI family zinc finger 2 | 0.0194161 |
| MACROD2 | MACRO domain containing 2 | 0.0190754 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0185717 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0183308 |
| INTS6 | integrator complex subunit 6 | 0.0182397 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0176975 |
| ENO1 | enolase 1, (alpha) | 0.0168632 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0167022 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0162897 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0161388 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.0159364 |
| TRIOBP | TRIO and F-actin binding protein | 0.0158191 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.015564 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0154466 |
| IRS1 | insulin receptor substrate 1 | 0.0152911 |
| SMAD3 | SMAD family member 3 | 0.0149981 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0147697 |
| ZNF438 | zinc finger protein 438 | 0.0147614 |
| TFCP2 | transcription factor CP2 | 0.01431 |
| MCL1 | myeloid cell leukemia 1 | 0.0138663 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0137988 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0136866 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0134463 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0131403 |
| EFNA5 | ephrin-A5 | 0.0130465 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.0129341 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0127714 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.012719 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0126082 |
| BMP2K | BMP2 inducible kinase | 0.0125603 |
| PLK2 | polo-like kinase 2 | 0.0124524 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | 0.0121667 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0121477 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0120953 |
| CPNE1 | copine I | 0.0120378 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0120202 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0119144 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0118354 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0116899 |
| AMOTL2 | angiomotin like 2 | 0.0116477 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0114967 |
| GPD2 | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 0.0113775 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.011122 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0110653 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0110383 |
| SHROOM3 | shroom family member 3 | 0.0110298 |
| PCNX4 | pecanex 4 | 0.0109944 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0107915 |
| CD93 | CD93 molecule | 0.0107889 |
| MYO5A | myosin VA (heavy chain 12, myoxin) | 0.0105728 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0103963 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0103854 |
| POTEF | POTE ankyrin domain family, member F | 0.0103398 |
| ARMH3 | armadillo like helical domain containing 3 | 0.0102736 |
| APP | amyloid beta (A4) precursor protein | 0.0102273 |
| YLPM1 | YLP motif containing 1 | 0.0101577 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0101365 |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.0101157 |
| FOXP1 | forkhead box P1 | 0.0100662 |
| XIRP2 | xin actin binding repeat containing 2 | 0.0100618 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.0100297 |
| TXK | TXK tyrosine kinase | 0.0100221 |
| DNMBP | dynamin binding protein | 0.0100042 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.00997682 |
| PDE7B | phosphodiesterase 7B | 0.00996707 |
| MYEOV | myeloma overexpressed | 0.00990733 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0098735 |
| CFAP44 | cilia and flagella associated protein 44 | 0.00986442 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0098515 |
| MFSD4B | major facilitator superfamily domain containing 4B | 0.00977506 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.00975867 |
| GLIS3 | GLIS family zinc finger 3 | 0.00973902 |
| SMAD6 | SMAD family member 6 | 0.00968099 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.258258 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.254546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149343 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125945 |
| RPS6 | ribosomal protein S6 | -0.122922 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.11321 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0990897 |
| RPL35A | ribosomal protein L35a | -0.0931278 |
| GOLGA4 | golgin A4 | -0.0887739 |
| S100A6 | S100 calcium binding protein A6 | -0.0737812 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0722013 |
| RBM39 | RNA binding motif protein 39 | -0.0705341 |
| ZNF292 | zinc finger protein 292 | -0.0704681 |
| RPS8 | ribosomal protein S8 | -0.0675361 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0673764 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0628264 |
| B2M | beta-2-microglobulin | -0.0593539 |
| PFN1 | profilin 1 | -0.0593242 |
| RPS19 | ribosomal protein S19 | -0.0583777 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0562235 |
| EVI5 | ecotropic viral integration site 5 | -0.0555836 |
| RPLP1 | ribosomal protein, large, P1 | -0.0526946 |
| RPL34 | ribosomal protein L34 | -0.0526155 |
| RPL9 | ribosomal protein L9 | -0.0513378 |
| RPL13A | ribosomal protein L13a | -0.050987 |
| GNAS | GNAS complex locus | -0.0501289 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.049871 |
| RPL12 | ribosomal protein L12 | -0.0494827 |
| RPS23 | ribosomal protein S23 | -0.0491825 |
| RPL37A | ribosomal protein L37a | -0.0490676 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.048596 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0484877 |
| RTN4 | reticulon 4 | -0.0484643 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0467464 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0461922 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0460424 |
| RPLP2 | ribosomal protein, large, P2 | -0.0450893 |
| RPL26 | ribosomal protein L26 | -0.0446458 |
| TMSB4X | thymosin beta 4, X-linked | -0.0444049 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0436157 |
| FTL | ferritin, light polypeptide | -0.042524 |
| RPL19 | ribosomal protein L19 | -0.0418239 |
| RPS25 | ribosomal protein S25 | -0.0417537 |
| RPLP0 | ribosomal protein, large, P0 | -0.0416925 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0407176 |
| RPS27A | ribosomal protein S27a | -0.0403682 |
| RPS24 | ribosomal protein S24 | -0.0403371 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.040171 |
| QKI | QKI, KH domain containing, RNA binding | -0.0391792 |
| TMSB10 | thymosin beta 10 | -0.0390753 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0390105 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0380123 |
| RPL11 | ribosomal protein L11 | -0.0379656 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0377553 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0370565 |
| RPS3 | ribosomal protein S3 | -0.0363791 |
| RPL36 | ribosomal protein L36 | -0.0363462 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0360849 |
| RPL7A | ribosomal protein L7a | -0.0360807 |
| RBM25 | RNA binding motif protein 25 | -0.0360136 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0359877 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0354133 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.035028 |
| CDC73 | cell division cycle 73 | -0.0347313 |
| RPL31 | ribosomal protein L31 | -0.0346475 |
| RPL32 | ribosomal protein L32 | -0.034354 |
| SEPTIN7 | septin 7 | -0.0341819 |
| MT2A | metallothionein 2A | -0.0339917 |
| TXNIP | thioredoxin interacting protein | -0.0338731 |
| USP3 | ubiquitin specific peptidase 3 | -0.0334779 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0334282 |
| RPS21 | ribosomal protein S21 | -0.0332536 |
| PHIP | pleckstrin homology domain interacting protein | -0.0331561 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0329847 |
| RPS11 | ribosomal protein S11 | -0.0329253 |
| JMJD1C | jumonji domain containing 1C | -0.0327635 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0327583 |
| RPS12 | ribosomal protein S12 | -0.03258 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0324931 |
| RPS13 | ribosomal protein S13 | -0.0324282 |
| SMNDC1 | survival motor neuron domain containing 1 | -0.0322016 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0320615 |
| CCNL1 | cyclin L1 | -0.0320161 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0318311 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0317326 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.031533 |
| TPI1 | triosephosphate isomerase 1 | -0.0313503 |
| HMGA1 | high mobility group AT-hook 1 | -0.0310589 |
| FBXO11 | F-box protein 11 | -0.0310142 |
| RPL8 | ribosomal protein L8 | -0.0308216 |
| S100A9 | S100 calcium binding protein A9 | -0.0307584 |
| TFG | TRK-fused gene | -0.0306396 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.030381 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0301844 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.030173 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0299513 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0298135 |
| PRRC2C | proline-rich coiled-coil 2C | -0.02978 |
| COG5 | component of oligomeric golgi complex 5 | -0.0296475 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0292799 |
