| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.167301 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.144229 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.139107 |
| AHNAK | AHNAK nucleoprotein | 0.13516 |
| CD44 | CD44 molecule (Indian blood group) | 0.114708 |
| VCAN | versican | 0.0968416 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0964193 |
| VIM | vimentin | 0.0962496 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.089459 |
| LDHA | lactate dehydrogenase A | 0.0860467 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0795422 |
| ENO1 | enolase 1, (alpha) | 0.0794445 |
| SFTPA2 | surfactant protein A2 | 0.0756535 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0737926 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.073328 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0711998 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0705117 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0668223 |
| STC1 | stanniocalcin 1 | 0.0661699 |
| GLIS3 | GLIS family zinc finger 3 | 0.0620071 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0618758 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0616013 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0615036 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0612348 |
| KYNU | kynureninase | 0.0601838 |
| BICC1 | BicC family RNA binding protein 1 | 0.0575697 |
| DST | dystonin | 0.0575618 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0571069 |
| TMSB4X | thymosin beta 4, X-linked | 0.0559966 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0559886 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0555808 |
| ASPH | aspartate beta-hydroxylase | 0.0547581 |
| APP | amyloid beta (A4) precursor protein | 0.0526922 |
| RND3 | Rho family GTPase 3 | 0.0520003 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.051927 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.051919 |
| HDAC9 | histone deacetylase 9 | 0.051323 |
| HMGA2 | high mobility group AT-hook 2 | 0.0508094 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0505762 |
| PLIN2 | perilipin 2 | 0.0499571 |
| RPS4X | ribosomal protein S4, X-linked | 0.0489435 |
| PGK1 | phosphoglycerate kinase 1 | 0.0484519 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0481868 |
| CTSB | cathepsin B | 0.0481611 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0479927 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0479085 |
| CALR | calreticulin | 0.0476797 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0461405 |
| CANX | calnexin | 0.0453787 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443097 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.044276 |
| SQSTM1 | sequestosome 1 | 0.0429398 |
| TXNIP | thioredoxin interacting protein | 0.0426127 |
| SMAD3 | SMAD family member 3 | 0.0425419 |
| VEGFA | vascular endothelial growth factor A | 0.0422804 |
| B2M | beta-2-microglobulin | 0.0412368 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0404565 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0404435 |
| EXT1 | exostosin glycosyltransferase 1 | 0.040365 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0398967 |
| THBS1 | thrombospondin 1 | 0.0389798 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0388687 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0384611 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.038239 |
| ARRDC3 | arrestin domain containing 3 | 0.0377423 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0371013 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0368944 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0365923 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0363808 |
| ANXA2 | annexin A2 | 0.0362985 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0354546 |
| FN1 | fibronectin 1 | 0.0343175 |
| ADM | adrenomedullin | 0.0335709 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0327203 |
| CDH13 | cadherin 13 | 0.0326107 |
| MT1X | metallothionein 1X | 0.0323059 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0320037 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0318642 |
| SYNJ2 | synaptojanin 2 | 0.0318517 |
| THBS2 | thrombospondin 2 | 0.0317859 |
| PCBP2 | poly(rC) binding protein 2 | 0.031756 |
| SDC4 | syndecan 4 | 0.0315226 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0305578 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0303209 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0292267 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0286849 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0285172 |
| MYOF | myoferlin | 0.0279293 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0277914 |
| TRIM55 | tripartite motif containing 55 | 0.0277528 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0275443 |
| HLA-E | major histocompatibility complex, class I, E | 0.0272827 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0267872 |
| CUL4B | cullin 4B | 0.0266875 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0260434 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259023 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0257589 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0257117 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0255212 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0254154 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | -0.0707126 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0706428 |
| NDRG1 | N-myc downstream regulated 1 | -0.0571516 |
| EGR1 | early growth response 1 | -0.0468731 |
| RTN4 | reticulon 4 | -0.0467281 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.038407 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0375561 |
| FRMD4A | FERM domain containing 4A | -0.036615 |
| RPL37A | ribosomal protein L37a | -0.0357037 |
| SBF2 | SET binding factor 2 | -0.0310015 |
| RPL35A | ribosomal protein L35a | -0.03044 |
| MKI67 | marker of proliferation Ki-67 | -0.0297753 |
| RPS3 | ribosomal protein S3 | -0.0269013 |
| CENPF | centromere protein F, 350/400kDa | -0.0267929 |
| JMJD1C | jumonji domain containing 1C | -0.0265978 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0263938 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0262323 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0262314 |
| RPL31 | ribosomal protein L31 | -0.0261777 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0260143 |
| RPL9 | ribosomal protein L9 | -0.0258101 |
| RPLP2 | ribosomal protein, large, P2 | -0.0251361 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0248805 |
| RPS17 | ribosomal protein S17 | -0.0245643 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0243255 |
| ATXN1 | ataxin 1 | -0.0241917 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0236734 |
| CTSD | cathepsin D | -0.0236609 |
| RPS13 | ribosomal protein S13 | -0.0226643 |
| NF1 | neurofibromin 1 | -0.0222445 |
| TMSB10 | thymosin beta 10 | -0.0222116 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0216234 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0216176 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0215126 |
| NABP1 | nucleic acid binding protein 1 | -0.0211403 |
| CEP95 | centrosomal protein 95kDa | -0.0207872 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0202963 |
| METTL15 | methyltransferase like 15 | -0.0198382 |
| KIF4A | kinesin family member 4A | -0.0194909 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0193499 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0192792 |
| CLIC4 | chloride intracellular channel 4 | -0.0192307 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0189161 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0186977 |
| RPS12 | ribosomal protein S12 | -0.0186396 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0184733 |
| PTMA | prothymosin, alpha | -0.0184659 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0183974 |
| RPS25 | ribosomal protein S25 | -0.0183659 |
| RPL36 | ribosomal protein L36 | -0.0179373 |
| RPS29 | ribosomal protein S29 | -0.0178326 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0178112 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0176466 |
| ATXN2 | ataxin 2 | -0.017405 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | -0.0173312 |
| SCARB1 | scavenger receptor class B, member 1 | -0.017193 |
| SETD5 | SET domain containing 5 | -0.0169872 |
| TAPBP | TAP binding protein (tapasin) | -0.0169269 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0167002 |
| RPS16 | ribosomal protein S16 | -0.0165664 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.016513 |
| LRRC7 | leucine rich repeat containing 7 | -0.0157734 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0157693 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0157427 |
| YEATS2 | YEATS domain containing 2 | -0.0157349 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0157073 |
| FRMD5 | FERM domain containing 5 | -0.0156828 |
| COG5 | component of oligomeric golgi complex 5 | -0.0156401 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0154864 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0154135 |
| TPX2 | TPX2, microtubule-associated | -0.0154029 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.015349 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0153231 |
| RPL13A | ribosomal protein L13a | -0.0151078 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0149192 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0149055 |
| RPS19 | ribosomal protein S19 | -0.014879 |
| ARF4 | ADP-ribosylation factor 4 | -0.0148243 |
| WDR44 | WD repeat domain 44 | -0.0148051 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0147036 |
| RAD51B | RAD51 paralog B | -0.014632 |
| MYO9A | myosin IXA | -0.0146202 |
| RASA2 | RAS p21 protein activator 2 | -0.0145023 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0144135 |
| TMEM41B | transmembrane protein 41B | -0.0142917 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.014113 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0141074 |
| DIAPH2 | diaphanous-related formin 2 | -0.0140563 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0139474 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0138912 |
| RPS27 | ribosomal protein S27 | -0.013852 |
| MAP1B | microtubule-associated protein 1B | -0.0138311 |
| RPS24 | ribosomal protein S24 | -0.0137391 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0136724 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0136365 |
| DIAPH3 | diaphanous-related formin 3 | -0.0136013 |
| KLHL24 | kelch-like family member 24 | -0.0135398 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0135363 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.01344 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0132648 |
