| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.156536 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.136888 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.112835 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.100215 |
| COL5A1 | collagen, type V, alpha 1 | 0.0989741 |
| POTEF | POTE ankyrin domain family, member F | 0.0975893 |
| AHNAK | AHNAK nucleoprotein | 0.0903764 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0816467 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0774188 |
| EGFR | epidermal growth factor receptor | 0.0756688 |
| CDH13 | cadherin 13 | 0.0752512 |
| CALR | calreticulin | 0.0697784 |
| HMGA2 | high mobility group AT-hook 2 | 0.0697478 |
| ENO1 | enolase 1, (alpha) | 0.0634743 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0627155 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0606039 |
| PRELID2 | PRELI domain containing 2 | 0.0536464 |
| FN1 | fibronectin 1 | 0.0504829 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497503 |
| ACTG1 | actin gamma 1 | 0.0486521 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0479239 |
| KYNU | kynureninase | 0.0471653 |
| VEGFC | vascular endothelial growth factor C | 0.0453296 |
| TNS3 | tensin 3 | 0.0452763 |
| VEGFA | vascular endothelial growth factor A | 0.0451648 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0442523 |
| NRXN3 | neurexin 3 | 0.0440332 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0426625 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0408711 |
| PRSS23 | protease, serine, 23 | 0.0408282 |
| TPM3 | tropomyosin 3 | 0.0406607 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0405899 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0403567 |
| VCL | vinculin | 0.0392916 |
| RUNX1 | runt-related transcription factor 1 | 0.0390871 |
| MSN | moesin | 0.0387374 |
| LAMB1 | laminin, beta 1 | 0.0378724 |
| PLEC | plectin | 0.0377503 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0373775 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0371387 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0370367 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0369423 |
| ITGAV | integrin, alpha V | 0.036199 |
| FLNA | filamin A, alpha | 0.0359124 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0342077 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0336672 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.033569 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0328888 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0328669 |
| SYNJ2 | synaptojanin 2 | 0.0327397 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0326845 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0325381 |
| C1D | C1D nuclear receptor corepressor | 0.0322143 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0321455 |
| FAM20C | family with sequence similarity 20, member C | 0.0318539 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0317322 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0316617 |
| FBN1 | fibrillin 1 | 0.0315189 |
| NBAS | neuroblastoma amplified sequence | 0.0313593 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0311447 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0309163 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.030769 |
| B2M | beta-2-microglobulin | 0.0306133 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0305989 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0298466 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0294268 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0293353 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0293189 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0291796 |
| MMP2 | matrix metallopeptidase 2 | 0.0286191 |
| VIM | vimentin | 0.0284956 |
| IL6 | interleukin 6 | 0.0282448 |
| FNIP1 | folliculin interacting protein 1 | 0.0281961 |
| INTS6 | integrator complex subunit 6 | 0.0281172 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0279916 |
| RAI14 | retinoic acid induced 14 | 0.0276831 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.027586 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0275279 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0269818 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0269393 |
| SETBP1 | SET binding protein 1 | 0.0268056 |
| EXOC4 | exocyst complex component 4 | 0.0266029 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.0264541 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0264188 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0264098 |
| TLN1 | talin 1 | 0.0261769 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.025955 |
| STXBP1 | syntaxin binding protein 1 | 0.0258877 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0258829 |
| SEPTIN9 | septin 9 | 0.0254138 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0253087 |
| MTREX | Mtr4 exosome RNA helicase | 0.0252042 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0251746 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0251603 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.025129 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0251153 |
| LAMB3 | laminin, beta 3 | 0.0246275 |
| ITM2B | integral membrane protein 2B | 0.0242323 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0241656 |
| SMYD3 | SET and MYND domain containing 3 | 0.0241251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.276042 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134154 |
| TMSB10 | thymosin beta 10 | -0.119178 |
| COL1A1 | collagen, type I, alpha 1 | -0.111579 |
| MT2A | metallothionein 2A | -0.0868362 |
| NDRG1 | N-myc downstream regulated 1 | -0.0864066 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0845769 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0811142 |
| FTL | ferritin, light polypeptide | -0.0810973 |
| FAM13A | family with sequence similarity 13, member A | -0.0756022 |
| COL1A2 | collagen, type I, alpha 2 | -0.0746564 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0742996 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0688905 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0678563 |
| H3-3B | H3.3 histone B | -0.0633246 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0629073 |
| RTN4 | reticulon 4 | -0.0573845 |
| OGA | O-GlcNAcase | -0.0540585 |
| PTMA | prothymosin, alpha | -0.0539439 |
| ARRDC3 | arrestin domain containing 3 | -0.0533561 |
| RLF | rearranged L-myc fusion | -0.052288 |
| ADM | adrenomedullin | -0.0507369 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.049368 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0466346 |
| UBC | ubiquitin C | -0.0461895 |
| ZNF292 | zinc finger protein 292 | -0.0453112 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0446237 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0445339 |
| PDE10A | phosphodiesterase 10A | -0.0444048 |
| TXNIP | thioredoxin interacting protein | -0.0424421 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0412191 |
| EMP1 | epithelial membrane protein 1 | -0.0411449 |
| CCNI | cyclin I | -0.0406461 |
| SPAG9 | sperm associated antigen 9 | -0.0405964 |
| GNAS | GNAS complex locus | -0.0400544 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0396557 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0387192 |
| TBC1D23 | TBC1 domain family, member 23 | -0.038529 |
| TFG | TRK-fused gene | -0.0379502 |
| CD99 | CD99 molecule | -0.0376622 |
| CALU | calumenin | -0.0371995 |
| RNF24 | ring finger protein 24 | -0.036896 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0365996 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0362425 |
| CANX | calnexin | -0.0360668 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0360222 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0356866 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0354161 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0347429 |
| GOLGA4 | golgin A4 | -0.0346362 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0344752 |
| HBP1 | HMG-box transcription factor 1 | -0.0342571 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0342477 |
| SRP54 | signal recognition particle 54kDa | -0.0341302 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0341074 |
| CADM1 | cell adhesion molecule 1 | -0.0332877 |
| COG5 | component of oligomeric golgi complex 5 | -0.0329743 |
| CD109 | CD109 molecule | -0.0327941 |
| FUS | FUS RNA binding protein | -0.0326751 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.032646 |
| ANXA2 | annexin A2 | -0.0325909 |
| MT1X | metallothionein 1X | -0.0324423 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0323797 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0322958 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0320251 |
| TUBB | tubulin, beta class I | -0.0314 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.031252 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0311238 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0300558 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0288534 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0287391 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0287285 |
| TXNRD1 | thioredoxin reductase 1 | -0.0285784 |
| RPL32 | ribosomal protein L32 | -0.0284384 |
| RPL34 | ribosomal protein L34 | -0.0279686 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0279253 |
| USP3 | ubiquitin specific peptidase 3 | -0.0277829 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0275914 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0274874 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0274033 |
| SETD5 | SET domain containing 5 | -0.027271 |
| RBM39 | RNA binding motif protein 39 | -0.0272309 |
| SEPTIN7 | septin 7 | -0.0271814 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0268336 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0266948 |
| TMEM39A | transmembrane protein 39A | -0.026657 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0266148 |
| IKBIP | IKBKB interacting protein | -0.026474 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0264635 |
| ZNF217 | zinc finger protein 217 | -0.0263722 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0262208 |
| H1-0 | H1.0 linker histone | -0.0260668 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0257072 |
| NUP54 | nucleoporin 54kDa | -0.0256277 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0256224 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0255919 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0255854 |
| ARF4 | ADP-ribosylation factor 4 | -0.0255729 |
| THY1 | Thy-1 cell surface antigen | -0.025566 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0255088 |
