| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.0850717 |
| TXNIP | thioredoxin interacting protein | 0.0508117 |
| POTEF | POTE ankyrin domain family, member F | 0.0446779 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.042182 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0387024 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0383788 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0351846 |
| TMEM156 | transmembrane protein 156 | 0.033174 |
| ENO1 | enolase 1, (alpha) | 0.0330965 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0329416 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.032526 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0322373 |
| MCL1 | myeloid cell leukemia 1 | 0.0311039 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0295162 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0291336 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0288976 |
| TCIM | transcriptional and immune response regulator | 0.0285422 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0266161 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0260939 |
| IFI44L | interferon-induced protein 44-like | 0.025964 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0255237 |
| B2M | beta-2-microglobulin | 0.0250813 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0244168 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0240576 |
| RASAL2 | RAS protein activator like 2 | 0.0236852 |
| SVIL | supervillin | 0.0226924 |
| MYOF | myoferlin | 0.0226907 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.022498 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0223953 |
| TPM3 | tropomyosin 3 | 0.0221801 |
| NTN4 | netrin 4 | 0.0220396 |
| FAT1 | FAT atypical cadherin 1 | 0.0210774 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0206923 |
| SMAD3 | SMAD family member 3 | 0.019816 |
| SEPTIN9 | septin 9 | 0.0195454 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0195391 |
| VEGFA | vascular endothelial growth factor A | 0.0194639 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0191364 |
| RPL3 | ribosomal protein L3 | 0.0190906 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0189428 |
| PCBP2 | poly(rC) binding protein 2 | 0.0189087 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0187427 |
| STC2 | stanniocalcin 2 | 0.0184536 |
| PKM | pyruvate kinase, muscle | 0.0181241 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0177444 |
| PLIN2 | perilipin 2 | 0.0176794 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0174889 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0173313 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0172095 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0167466 |
| SFTPA2 | surfactant protein A2 | 0.0166435 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0166101 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0161707 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0161085 |
| AHNAK | AHNAK nucleoprotein | 0.0160609 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.015976 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0158914 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0157128 |
| MLPH | melanophilin | 0.0157056 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0153241 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0153022 |
| ATP9A | ATPase, class II, type 9A | 0.0151314 |
| ITGAV | integrin, alpha V | 0.0150803 |
| FAM13A | family with sequence similarity 13, member A | 0.0150629 |
| VEGFC | vascular endothelial growth factor C | 0.0150624 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0150563 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0147725 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.01477 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.014594 |
| NOTCH2 | notch 2 | 0.0144256 |
| GPATCH2L | G patch domain containing 2-like | 0.0142834 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.014283 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0141427 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0141288 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0140246 |
| ACTG1 | actin gamma 1 | 0.0139406 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.013761 |
| CTSB | cathepsin B | 0.0134823 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0134643 |
| PCDH7 | protocadherin 7 | 0.0132414 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0130994 |
| FLNA | filamin A, alpha | 0.0126563 |
| EFNA5 | ephrin-A5 | 0.0125739 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0125663 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0124993 |
| ITGB4 | integrin, beta 4 | 0.0124901 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0124033 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0122023 |
| NBEA | neurobeachin | 0.0121869 |
| AREG | amphiregulin | 0.0120965 |
| ECE1 | endothelin converting enzyme 1 | 0.0119621 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0119549 |
| ANGPTL4 | angiopoietin-like 4 | 0.0119179 |
| RND3 | Rho family GTPase 3 | 0.0118624 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0116625 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | 0.0116108 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0115711 |
| FOSL1 | FOS-like antigen 1 | 0.0115504 |
| SGMS2 | sphingomyelin synthase 2 | 0.0115339 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0114367 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.274232 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.255753 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.223712 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.203203 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.17473 |
| CANX | calnexin | -0.135492 |
| PTMA | prothymosin, alpha | -0.130787 |
| SQSTM1 | sequestosome 1 | -0.0986517 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0885929 |
| FN1 | fibronectin 1 | -0.0599273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0596161 |
| VCL | vinculin | -0.0563582 |
| RPS6 | ribosomal protein S6 | -0.0523413 |
| HLA-B | major histocompatibility complex, class I, B | -0.0517691 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0513273 |
| SPAG9 | sperm associated antigen 9 | -0.049508 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0490833 |
| GNAS | GNAS complex locus | -0.0484684 |
| TMSB10 | thymosin beta 10 | -0.0477075 |
| H1-0 | H1.0 linker histone | -0.047192 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0468923 |
| GOLGA4 | golgin A4 | -0.0461802 |
| IER3 | immediate early response 3 | -0.0460233 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0459143 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0457424 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0453237 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0450998 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0449699 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.043633 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0415771 |
| HDLBP | high density lipoprotein binding protein | -0.0414419 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.040936 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0407754 |
| SUCO | SUN domain containing ossification factor | -0.0406783 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0404998 |
| RPS24 | ribosomal protein S24 | -0.0404768 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0402501 |
| FTL | ferritin, light polypeptide | -0.038935 |
| CEP350 | centrosomal protein 350kDa | -0.0383923 |
| RPL26 | ribosomal protein L26 | -0.038116 |
| OGA | O-GlcNAcase | -0.0378406 |
| TMEM263 | transmembrane protein 263 | -0.0378266 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0375291 |
| CENPF | centromere protein F, 350/400kDa | -0.0372012 |
| ITGA1 | integrin, alpha 1 | -0.0366972 |
| SYT1 | synaptotagmin I | -0.0366675 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0365232 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0362244 |
| S100A6 | S100 calcium binding protein A6 | -0.0360882 |
| TMEM165 | transmembrane protein 165 | -0.035951 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.035896 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0357236 |
| RBM39 | RNA binding motif protein 39 | -0.0354079 |
| AHR | aryl hydrocarbon receptor | -0.0352624 |
| RPL35A | ribosomal protein L35a | -0.0351716 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0351136 |
| OSMR | oncostatin M receptor | -0.0350545 |
| RRBP1 | ribosome binding protein 1 | -0.0344201 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0342818 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0341413 |
| ARF1 | ADP-ribosylation factor 1 | -0.0340529 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0338627 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0335692 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0333055 |
| NDRG1 | N-myc downstream regulated 1 | -0.0332243 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0332096 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0327134 |
| RAB1A | RAB1A, member RAS oncogene family | -0.032675 |
| CALU | calumenin | -0.0325773 |
| TMSB4X | thymosin beta 4, X-linked | -0.0316367 |
| AFF4 | AF4/FMR2 family, member 4 | -0.030959 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0306153 |
| VMP1 | vacuole membrane protein 1 | -0.0305063 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0302583 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301841 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.030109 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0300622 |
| WDR45B | WD repeat domain 45B | -0.0296775 |
| RPL38 | ribosomal protein L38 | -0.0296287 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0295103 |
| NRG1 | neuregulin 1 | -0.0291017 |
| MKI67 | marker of proliferation Ki-67 | -0.0290834 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0288285 |
| ZNF217 | zinc finger protein 217 | -0.0286532 |
| HM13 | histocompatibility (minor) 13 | -0.0280985 |
| RPS5 | ribosomal protein S5 | -0.0279327 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0279148 |
| RPS21 | ribosomal protein S21 | -0.0277796 |
| MTDH | metadherin | -0.0277299 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0275911 |
| RPL34 | ribosomal protein L34 | -0.0268312 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0267947 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0267093 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0262583 |
| TPR | translocated promoter region, nuclear basket protein | -0.0261826 |
| RPS29 | ribosomal protein S29 | -0.0260319 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.025599 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0255456 |
| CLINT1 | clathrin interactor 1 | -0.0254705 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0254694 |
