| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MACC1 | metastasis associated in colon cancer 1 | 0.0943278 |
| NEBL | nebulette | 0.0742394 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0647374 |
| FAT1 | FAT atypical cadherin 1 | 0.0600286 |
| POTEF | POTE ankyrin domain family, member F | 0.0566213 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0529416 |
| BCL2L1 | BCL2-like 1 | 0.0499149 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0495046 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0483042 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0447737 |
| RPL3 | ribosomal protein L3 | 0.0444097 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0441839 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0435755 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0428841 |
| PCBP2 | poly(rC) binding protein 2 | 0.0419181 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0401083 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0395222 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0384203 |
| YAP1 | Yes-associated protein 1 | 0.0378384 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0372595 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0364423 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0350992 |
| ACTG1 | actin gamma 1 | 0.0345446 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.034232 |
| DSPP | dentin sialophosphoprotein | 0.0341656 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0341124 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0334288 |
| DIAPH1 | diaphanous-related formin 1 | 0.0327614 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0327003 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.032687 |
| ETV6 | ets variant 6 | 0.0325138 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0317846 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0308043 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0301475 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.029847 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0283813 |
| RPS3 | ribosomal protein S3 | 0.0282395 |
| EZR | ezrin | 0.0279521 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0273954 |
| FLNA | filamin A, alpha | 0.0273691 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.027369 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.02645 |
| MYOF | myoferlin | 0.0259392 |
| RPS12 | ribosomal protein S12 | 0.0253886 |
| ANXA11 | annexin A11 | 0.0248328 |
| MCL1 | myeloid cell leukemia 1 | 0.0238037 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0231402 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0229008 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0228264 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.022745 |
| SKAP2 | src kinase associated phosphoprotein 2 | 0.0223605 |
| PKP4 | plakophilin 4 | 0.0220096 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0218911 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.021856 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0214596 |
| LDHA | lactate dehydrogenase A | 0.021402 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0210102 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208034 |
| SMAD3 | SMAD family member 3 | 0.0206989 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0206408 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0204534 |
| RPS2 | ribosomal protein S2 | 0.0198167 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0197686 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0196988 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0196718 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0195269 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0193362 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0192534 |
| SMYD3 | SET and MYND domain containing 3 | 0.0192107 |
| CENPF | centromere protein F, 350/400kDa | 0.0190073 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0189405 |
| ENO1 | enolase 1, (alpha) | 0.0187565 |
| WWOX | WW domain containing oxidoreductase | 0.0186994 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa | 0.0186436 |
| PLSCR1 | phospholipid scramblase 1 | 0.0186223 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0184856 |
| ATL2 | atlastin GTPase 2 | 0.018113 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0181081 |
| MYO5B | myosin VB | 0.0180324 |
| RPL4 | ribosomal protein L4 | 0.0177041 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0176088 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0175846 |
| RNF213 | ring finger protein 213 | 0.017555 |
| KIAA1217 | KIAA1217 | 0.0173718 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.017344 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0172715 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0171524 |
| RPS7 | ribosomal protein S7 | 0.0169964 |
| TXNIP | thioredoxin interacting protein | 0.0169336 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0166918 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0166882 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0166839 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0165085 |
| PRELID2 | PRELI domain containing 2 | 0.0159824 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.015714 |
| ADAR | adenosine deaminase, RNA-specific | 0.015645 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0156242 |
| TPM3 | tropomyosin 3 | 0.0155324 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0154315 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0154172 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.287513 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.159586 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115893 |
| FTL | ferritin, light polypeptide | -0.105922 |
| TMSB10 | thymosin beta 10 | -0.102017 |
| GNAS | GNAS complex locus | -0.086395 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0861398 |
| RPS6 | ribosomal protein S6 | -0.0827319 |
| IER3 | immediate early response 3 | -0.0810301 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0766156 |
| GOLGA4 | golgin A4 | -0.0747627 |
| HM13 | histocompatibility (minor) 13 | -0.0688111 |
| H1-0 | H1.0 linker histone | -0.0685246 |
| TMEM123 | transmembrane protein 123 | -0.068189 |
| RPL35A | ribosomal protein L35a | -0.0677595 |
| CANX | calnexin | -0.0648057 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0557384 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0551159 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0541776 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0539811 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0512419 |
| RPS24 | ribosomal protein S24 | -0.0503193 |
| KRT18 | keratin 18, type I | -0.047424 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0472735 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0469075 |
| JMJD1C | jumonji domain containing 1C | -0.0465203 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0465132 |
| NDRG1 | N-myc downstream regulated 1 | -0.0463096 |
| RPLP1 | ribosomal protein, large, P1 | -0.0460217 |
| CCND1 | cyclin D1 | -0.0457394 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0454085 |
| HLA-A | major histocompatibility complex, class I, A | -0.0453928 |
| S100A10 | S100 calcium binding protein A10 | -0.0452334 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0441336 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0434161 |
| TOP1 | topoisomerase (DNA) I | -0.0432999 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0427877 |
| RTN3 | reticulon 3 | -0.0413849 |
| CTSD | cathepsin D | -0.0412181 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0406773 |
| RBM39 | RNA binding motif protein 39 | -0.0403138 |
| RPS21 | ribosomal protein S21 | -0.039826 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0393543 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0390737 |
| CDK13 | cyclin-dependent kinase 13 | -0.0387663 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0379919 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0379698 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0378924 |
| SQSTM1 | sequestosome 1 | -0.0378779 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0375878 |
| RPS25 | ribosomal protein S25 | -0.0370421 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0368575 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0368413 |
| S100A6 | S100 calcium binding protein A6 | -0.036538 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0362485 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0360533 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0358785 |
| SETD5 | SET domain containing 5 | -0.035684 |
| PERP | PERP, TP53 apoptosis effector | -0.0356457 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0356352 |
| HMGA1 | high mobility group AT-hook 1 | -0.0356003 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0354863 |
| HDLBP | high density lipoprotein binding protein | -0.0354179 |
| RPL34 | ribosomal protein L34 | -0.0352345 |
| RPL8 | ribosomal protein L8 | -0.0345359 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0343662 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0343497 |
| RPL19 | ribosomal protein L19 | -0.033891 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.033889 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0337804 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0335288 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0334998 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0333197 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0330945 |
| RPL28 | ribosomal protein L28 | -0.0330331 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0325183 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0316291 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.031258 |
| S100A2 | S100 calcium binding protein A2 | -0.031222 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0312115 |
| RHEB | Ras homolog enriched in brain | -0.0312059 |
| MTDH | metadherin | -0.0308327 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0304167 |
| RPS29 | ribosomal protein S29 | -0.0299529 |
| FUS | FUS RNA binding protein | -0.0298968 |
| MORF4L2 | mortality factor 4 like 2 | -0.0298754 |
| RPL32 | ribosomal protein L32 | -0.0297975 |
| RPS13 | ribosomal protein S13 | -0.0295802 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0295288 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0292867 |
| MXD1 | MAX dimerization protein 1 | -0.0292634 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0290233 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287491 |
| NFIA | nuclear factor I/A | -0.0282425 |
| TPM4 | tropomyosin 4 | -0.0280545 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0279831 |
| RIOK3 | RIO kinase 3 | -0.0277356 |
| COG5 | component of oligomeric golgi complex 5 | -0.0277163 |
| GOLGB1 | golgin B1 | -0.0277027 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0276614 |
