| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.249328 |
| ACTG1 | actin gamma 1 | 0.172819 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102102 |
| RCOR1 | REST corepressor 1 | 0.0909474 |
| HMGA2 | high mobility group AT-hook 2 | 0.0826246 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0767206 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0742213 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0698424 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0634475 |
| POTEF | POTE ankyrin domain family, member F | 0.0633242 |
| RPL3 | ribosomal protein L3 | 0.0594169 |
| AHNAK | AHNAK nucleoprotein | 0.0526663 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0505538 |
| LAMA4 | laminin, alpha 4 | 0.047713 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0446504 |
| FAT1 | FAT atypical cadherin 1 | 0.0436628 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0428239 |
| ENO1 | enolase 1, (alpha) | 0.0401622 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0390288 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0387073 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0385625 |
| GPC5 | glypican 5 | 0.0380493 |
| CPOX | coproporphyrinogen oxidase | 0.0377843 |
| SGMS2 | sphingomyelin synthase 2 | 0.03619 |
| SEPTIN9 | septin 9 | 0.0359567 |
| NUP50 | nucleoporin 50kDa | 0.0347839 |
| HOMER1 | homer scaffolding protein 1 | 0.0340505 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0334416 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0321797 |
| SNX9 | sorting nexin 9 | 0.0318707 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0315072 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0314102 |
| EFNB2 | ephrin-B2 | 0.0312738 |
| RPS12 | ribosomal protein S12 | 0.0308781 |
| EZR | ezrin | 0.0304869 |
| DSPP | dentin sialophosphoprotein | 0.0303369 |
| PCBP2 | poly(rC) binding protein 2 | 0.0302948 |
| FHL2 | four and a half LIM domains 2 | 0.0298728 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0298707 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0292749 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0290973 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0290797 |
| IGSF9B | immunoglobulin superfamily, member 9B | 0.0289371 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0288988 |
| SMAD3 | SMAD family member 3 | 0.0287027 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.028271 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0282068 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0274156 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0270818 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0269686 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0265295 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0253013 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0248081 |
| ABR | active BCR-related | 0.0246767 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0241898 |
| SH3RF2 | SH3 domain containing ring finger 2 | 0.0236442 |
| EGFR | epidermal growth factor receptor | 0.0235705 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232898 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0227127 |
| CMIP | c-Maf inducing protein | 0.0227067 |
| RPL4 | ribosomal protein L4 | 0.0226787 |
| CLDND1 | claudin domain containing 1 | 0.0224789 |
| ITGA6 | integrin, alpha 6 | 0.0224713 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.0216907 |
| SET | SET nuclear proto-oncogene | 0.021658 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0214912 |
| CENPF | centromere protein F, 350/400kDa | 0.0214831 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0209984 |
| RASAL2 | RAS protein activator like 2 | 0.0207746 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0207723 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.0207138 |
| VCL | vinculin | 0.0205926 |
| DUSP4 | dual specificity phosphatase 4 | 0.0204863 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.020161 |
| TPM4 | tropomyosin 4 | 0.0201001 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0199824 |
| EGR1 | early growth response 1 | 0.0187979 |
| RPS3 | ribosomal protein S3 | 0.0187393 |
| LAMB3 | laminin, beta 3 | 0.018717 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.018612 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0186048 |
| FHIT | fragile histidine triad | 0.018545 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0184843 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0184364 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0183141 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0183135 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0182664 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0180551 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.017999 |
| ANXA2 | annexin A2 | 0.0177502 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0177259 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0176988 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.0174161 |
| FOSL1 | FOS-like antigen 1 | 0.0173178 |
| FAM120A | family with sequence similarity 120A | 0.0172644 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0170231 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0168158 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0168086 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0166444 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0164068 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.218873 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.209809 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.144259 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.123092 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.105029 |
| OXR1 | oxidation resistance 1 | -0.0928367 |
| TMSB10 | thymosin beta 10 | -0.0803547 |
| IER3 | immediate early response 3 | -0.0793293 |
| PTMA | prothymosin, alpha | -0.0780594 |
| AREG | amphiregulin | -0.0739425 |
| RPS24 | ribosomal protein S24 | -0.0705426 |
| TXNRD1 | thioredoxin reductase 1 | -0.0604572 |
| RPS6 | ribosomal protein S6 | -0.060365 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0600751 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0588445 |
| RNF43 | ring finger protein 43 | -0.0584337 |
| GOLGA4 | golgin A4 | -0.0574527 |
| LMO7 | LIM domain 7 | -0.0562936 |
| RUNX2 | runt-related transcription factor 2 | -0.0520724 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0505614 |
| TOP1 | topoisomerase (DNA) I | -0.0498522 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0491648 |
| RPL35A | ribosomal protein L35a | -0.0482935 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0465286 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0460239 |
| SERINC5 | serine incorporator 5 | -0.045338 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0449567 |
| COG5 | component of oligomeric golgi complex 5 | -0.0443982 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0410313 |
| USP3 | ubiquitin specific peptidase 3 | -0.0402047 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.0396944 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0387938 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0387342 |
| RPL12 | ribosomal protein L12 | -0.0371011 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0365329 |
| S100A10 | S100 calcium binding protein A10 | -0.0363762 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0361614 |
| NF1 | neurofibromin 1 | -0.0356289 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0349486 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0348168 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0343797 |
| SLMAP | sarcolemma associated protein | -0.0343369 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0343312 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0341847 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0332768 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0329801 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0326873 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0318404 |
| RBM25 | RNA binding motif protein 25 | -0.0318259 |
| RPL11 | ribosomal protein L11 | -0.031611 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0313262 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0309074 |
| MAP4 | microtubule-associated protein 4 | -0.0303263 |
| NEMF | nuclear export mediator factor | -0.030148 |
| RBM39 | RNA binding motif protein 39 | -0.0301192 |
| ATP11B | ATPase, class VI, type 11B | -0.0298741 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0297664 |
| RPL34 | ribosomal protein L34 | -0.0297633 |
| MTAP | methylthioadenosine phosphorylase | -0.0295342 |
| RPS19 | ribosomal protein S19 | -0.0294316 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0293754 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0292856 |
| RPL8 | ribosomal protein L8 | -0.0289539 |
| CLTC | clathrin, heavy chain (Hc) | -0.0288951 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0281841 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0278168 |
| NEK7 | NIMA-related kinase 7 | -0.0277469 |
| RNF145 | ring finger protein 145 | -0.0276232 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0274109 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0270828 |
| SBF2 | SET binding factor 2 | -0.0269818 |
| RPL32 | ribosomal protein L32 | -0.0269225 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0267872 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.026512 |
| HDAC2 | histone deacetylase 2 | -0.0263703 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0263602 |
| OGA | O-GlcNAcase | -0.0263088 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0263087 |
| RLF | rearranged L-myc fusion | -0.0261853 |
| RPS15 | ribosomal protein S15 | -0.0261459 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0261119 |
| RPLP1 | ribosomal protein, large, P1 | -0.0260685 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0260652 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0259296 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0258983 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0258089 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0256624 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0255777 |
| MT2A | metallothionein 2A | -0.0255399 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0250483 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0250283 |
| FOXO1 | forkhead box O1 | -0.0245629 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0242826 |
| ZNF292 | zinc finger protein 292 | -0.0242807 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0242651 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0241523 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0241413 |
| RPLP2 | ribosomal protein, large, P2 | -0.0238657 |
| FERMT1 | fermitin family member 1 | -0.0238488 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0236886 |
