| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.28703 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.108399 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.089088 |
| VCL | vinculin | 0.0862162 |
| TNS3 | tensin 3 | 0.0794198 |
| WWOX | WW domain containing oxidoreductase | 0.0716202 |
| INTS6 | integrator complex subunit 6 | 0.0592276 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0576714 |
| YAP1 | Yes-associated protein 1 | 0.0534291 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0521375 |
| SYT1 | synaptotagmin I | 0.0511043 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0475129 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0472349 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.043149 |
| DSPP | dentin sialophosphoprotein | 0.0401822 |
| CDK6 | cyclin-dependent kinase 6 | 0.0390217 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0388294 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0387236 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0352732 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0344002 |
| LMO7 | LIM domain 7 | 0.0328036 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0318335 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.031397 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0308502 |
| BMP5 | bone morphogenetic protein 5 | 0.0298131 |
| RAD51B | RAD51 paralog B | 0.0296946 |
| DST | dystonin | 0.0281885 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0281885 |
| MACC1 | metastasis associated in colon cancer 1 | 0.027676 |
| PCDH9 | protocadherin 9 | 0.0262919 |
| SMAD3 | SMAD family member 3 | 0.0261597 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0249986 |
| PHF14 | PHD finger protein 14 | 0.0247683 |
| HDAC4 | histone deacetylase 4 | 0.0247579 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.024459 |
| CDH13 | cadherin 13 | 0.0243952 |
| SPATA13 | spermatogenesis associated 13 | 0.0235166 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0232684 |
| AXIN2 | axin 2 | 0.0226903 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) | 0.0225479 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0222527 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0222512 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0217194 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0211135 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0210133 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0197251 |
| EPHB2 | EPH receptor B2 | 0.0196946 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.019584 |
| RASSF6 | Ras association (RalGDS/AF-6) domain family member 6 | 0.0195009 |
| ATXN7L1 | ataxin 7-like 1 | 0.0192957 |
| BCL2L1 | BCL2-like 1 | 0.0188185 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.018799 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0187598 |
| MED13 | mediator complex subunit 13 | 0.0182275 |
| STK38L | serine/threonine kinase 38 like | 0.0182183 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0180882 |
| FOXP1 | forkhead box P1 | 0.0179369 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0177891 |
| TSPAN5 | tetraspanin 5 | 0.0176723 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0173587 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0172827 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0172331 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | 0.01707 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0168309 |
| TMEM123 | transmembrane protein 123 | 0.0166057 |
| SMOC2 | SPARC related modular calcium binding 2 | 0.016582 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0163498 |
| SYK | spleen tyrosine kinase | 0.0162414 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.0162345 |
| KLF12 | Kruppel-like factor 12 | 0.0158892 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0158596 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0158143 |
| BICC1 | BicC family RNA binding protein 1 | 0.0156655 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0155532 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0154514 |
| SERINC5 | serine incorporator 5 | 0.0154239 |
| MTAP | methylthioadenosine phosphorylase | 0.0153867 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | 0.0153603 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.0153554 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.015151 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0150755 |
| CD46 | CD46 molecule, complement regulatory protein | 0.015038 |
| CEP112 | centrosomal protein 112kDa | 0.0150029 |
| TCF12 | transcription factor 12 | 0.0149473 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0149189 |
| TMEM163 | transmembrane protein 163 | 0.0148438 |
| HDAC8 | histone deacetylase 8 | 0.0148276 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0145912 |
| SMYD3 | SET and MYND domain containing 3 | 0.0145199 |
| DIAPH2 | diaphanous-related formin 2 | 0.0144047 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0143199 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0140823 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0140352 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0139759 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0139504 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.013819 |
| TOX3 | TOX high mobility group box family member 3 | 0.0137815 |
| VIL1 | villin 1 | 0.0137441 |
| EXOC4 | exocyst complex component 4 | 0.0136502 |
| MCC | mutated in colorectal cancers | 0.013602 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.10143 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0969145 |
| PTMA | prothymosin, alpha | -0.094469 |
| NDRG1 | N-myc downstream regulated 1 | -0.0819123 |
| RPL37A | ribosomal protein L37a | -0.0811614 |
| RPS27A | ribosomal protein S27a | -0.0793825 |
| RPL35A | ribosomal protein L35a | -0.078208 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0774084 |
| RPS6 | ribosomal protein S6 | -0.0767906 |
| TMSB10 | thymosin beta 10 | -0.0757768 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0747476 |
| GOLGA4 | golgin A4 | -0.0713139 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706863 |
| HMGA1 | high mobility group AT-hook 1 | -0.0616195 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0608537 |
| FTL | ferritin, light polypeptide | -0.0591467 |
| UBC | ubiquitin C | -0.0556261 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0547918 |
| PKM | pyruvate kinase, muscle | -0.0542969 |
| FLNB | filamin B, beta | -0.0532079 |
| RPS19 | ribosomal protein S19 | -0.0530432 |
| RPL23 | ribosomal protein L23 | -0.0523564 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0497881 |
| VIM | vimentin | -0.0476642 |
| RPL31 | ribosomal protein L31 | -0.0467607 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0467046 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0466219 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0459578 |
| RPL26 | ribosomal protein L26 | -0.0450969 |
| ANXA2 | annexin A2 | -0.0446435 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0439508 |
| RPS12 | ribosomal protein S12 | -0.0428157 |
| ITGA6 | integrin, alpha 6 | -0.042568 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0425581 |
| CCND1 | cyclin D1 | -0.0425159 |
| TPM4 | tropomyosin 4 | -0.041842 |
| RPS13 | ribosomal protein S13 | -0.041838 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0397373 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0392748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0392174 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0390274 |
| ARF4 | ADP-ribosylation factor 4 | -0.0376622 |
| RPS25 | ribosomal protein S25 | -0.0374882 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0366951 |
| RPS3 | ribosomal protein S3 | -0.0365764 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0362792 |
| SQSTM1 | sequestosome 1 | -0.0357703 |
| RPS17 | ribosomal protein S17 | -0.0356041 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0348399 |
| RTN4 | reticulon 4 | -0.0346034 |
| ANLN | anillin, actin binding protein | -0.0345835 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0341787 |
| RPL12 | ribosomal protein L12 | -0.0336472 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0335888 |
| EMP1 | epithelial membrane protein 1 | -0.0330374 |
| SNX9 | sorting nexin 9 | -0.0329614 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324893 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0324746 |
| KRT8 | keratin 8, type II | -0.0323247 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323093 |
| RPS8 | ribosomal protein S8 | -0.0322949 |
| ASPH | aspartate beta-hydroxylase | -0.0320374 |
| COG5 | component of oligomeric golgi complex 5 | -0.0319705 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0319169 |
| ITGB4 | integrin, beta 4 | -0.0318873 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0318629 |
| CANX | calnexin | -0.0318616 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0303638 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0298942 |
| RPS5 | ribosomal protein S5 | -0.0298273 |
| MT2A | metallothionein 2A | -0.0297703 |
| FNIP1 | folliculin interacting protein 1 | -0.0293512 |
| RPL28 | ribosomal protein L28 | -0.0292476 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0291983 |
| KRT18 | keratin 18, type I | -0.0288213 |
| S100A10 | S100 calcium binding protein A10 | -0.028395 |
| RPL11 | ribosomal protein L11 | -0.0281185 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0275143 |
| ZNF292 | zinc finger protein 292 | -0.0274812 |
| S100A6 | S100 calcium binding protein A6 | -0.0272634 |
| RBP1 | retinol binding protein 1, cellular | -0.0269914 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266302 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0266031 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0265299 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0263916 |
| EGR1 | early growth response 1 | -0.0263905 |
| S100A9 | S100 calcium binding protein A9 | -0.0259944 |
| RPS16 | ribosomal protein S16 | -0.0258912 |
| RPL35 | ribosomal protein L35 | -0.0258435 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0257597 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | -0.0254978 |
| EZR | ezrin | -0.0249539 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0246468 |
| SRPK2 | SRSF protein kinase 2 | -0.0246415 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0245555 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0245087 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0243871 |
| RPL7A | ribosomal protein L7a | -0.0240476 |
| RPLP2 | ribosomal protein, large, P2 | -0.0239507 |
| JUN | jun proto-oncogene | -0.0238627 |
