| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the ETC-206_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0849579 |
| MYO10 | myosin X | 0.0754537 |
| CD44 | CD44 molecule (Indian blood group) | 0.0661259 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0592105 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0524385 |
| AHNAK | AHNAK nucleoprotein | 0.0482374 |
| ASPH | aspartate beta-hydroxylase | 0.0476412 |
| GLIS3 | GLIS family zinc finger 3 | 0.0452426 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0396777 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.039387 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0386241 |
| NOTCH2 | notch 2 | 0.0339335 |
| PCBP2 | poly(rC) binding protein 2 | 0.0333362 |
| RPL3 | ribosomal protein L3 | 0.0328755 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0321238 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0283499 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0274123 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0269128 |
| LOX | lysyl oxidase | 0.0244883 |
| POTEF | POTE ankyrin domain family, member F | 0.0243587 |
| MCL1 | myeloid cell leukemia 1 | 0.0243038 |
| STC1 | stanniocalcin 1 | 0.0242686 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0238142 |
| MT2A | metallothionein 2A | 0.0236194 |
| MMP2 | matrix metallopeptidase 2 | 0.0235077 |
| SMAD3 | SMAD family member 3 | 0.023265 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0230374 |
| ENO1 | enolase 1, (alpha) | 0.023014 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0219252 |
| MSN | moesin | 0.0219192 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0205252 |
| APP | amyloid beta (A4) precursor protein | 0.0205141 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0204224 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0195894 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0194984 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0194823 |
| EGFR | epidermal growth factor receptor | 0.0193916 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0190113 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0190061 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0186449 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0182464 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0181168 |
| HMGA2 | high mobility group AT-hook 2 | 0.0177578 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0176972 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0171109 |
| TLN1 | talin 1 | 0.0170724 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0169794 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0169548 |
| C1D | C1D nuclear receptor corepressor | 0.0169141 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.016413 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0162059 |
| INTS6 | integrator complex subunit 6 | 0.0161586 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0155416 |
| VEGFA | vascular endothelial growth factor A | 0.0154984 |
| SFPQ | splicing factor proline/glutamine-rich | 0.015495 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0151641 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0149946 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0147179 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0146051 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0142386 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.014119 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0140507 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0138701 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0134986 |
| AMOTL1 | angiomotin like 1 | 0.013297 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.013257 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0131431 |
| ITGAV | integrin, alpha V | 0.0131237 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0125641 |
| CYTH3 | cytohesin 3 | 0.0124691 |
| JAG1 | jagged 1 | 0.0123975 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.012273 |
| PRICKLE2 | prickle homolog 2 (Drosophila) | 0.0121643 |
| ARHGAP31 | Rho GTPase activating protein 31 | 0.0120114 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0118947 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0118896 |
| WLS | wntless Wnt ligand secretion mediator | 0.0118771 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.011795 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0117869 |
| FSTL1 | follistatin-like 1 | 0.0117381 |
| RPL4 | ribosomal protein L4 | 0.011685 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0114849 |
| COL3A1 | collagen, type III, alpha 1 | 0.0113905 |
| HBEGF | heparin-binding EGF-like growth factor | 0.0113868 |
| RCOR1 | REST corepressor 1 | 0.0113092 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0112904 |
| SET | SET nuclear proto-oncogene | 0.0112115 |
| TSPYL2 | TSPY-like 2 | 0.0111636 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0110555 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.010985 |
| TNS1 | tensin 1 | 0.0108881 |
| ITGA11 | integrin, alpha 11 | 0.010834 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.010828 |
| PLEC | plectin | 0.0107594 |
| NAV1 | neuron navigator 1 | 0.0106325 |
| GPATCH2L | G patch domain containing 2-like | 0.010545 |
| ETV3 | ets variant 3 | 0.0105216 |
| THBS2 | thrombospondin 2 | 0.0104227 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0103888 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.010342 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.369622 |
| VIM | vimentin | -0.27012 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.237895 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.15098 |
| COL1A1 | collagen, type I, alpha 1 | -0.139876 |
| TMSB10 | thymosin beta 10 | -0.0784285 |
| HLA-B | major histocompatibility complex, class I, B | -0.0756133 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0732909 |
| NDRG1 | N-myc downstream regulated 1 | -0.0723362 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0706869 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0692185 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0684945 |
| MMP1 | matrix metallopeptidase 1 | -0.0649314 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0643366 |
| RPS6 | ribosomal protein S6 | -0.0616236 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0614859 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0584498 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0567764 |
| FTL | ferritin, light polypeptide | -0.0564426 |
| RPL34 | ribosomal protein L34 | -0.0534721 |
| TPM4 | tropomyosin 4 | -0.0512719 |
| EMP1 | epithelial membrane protein 1 | -0.0506593 |
| CAVIN1 | caveolae associated protein 1 | -0.0493266 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0490497 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0478365 |
| RPL35A | ribosomal protein L35a | -0.0476995 |
| GOLGA4 | golgin A4 | -0.0455306 |
| IER3 | immediate early response 3 | -0.044902 |
| CANX | calnexin | -0.0438921 |
| PTMA | prothymosin, alpha | -0.0437833 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0426734 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0423416 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0388194 |
| COL6A1 | collagen, type VI, alpha 1 | -0.037953 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0373495 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0372987 |
| MMP12 | matrix metallopeptidase 12 | -0.0363712 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0357034 |
| S100A6 | S100 calcium binding protein A6 | -0.0355071 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0352037 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0351288 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0344459 |
| RRBP1 | ribosome binding protein 1 | -0.0342841 |
| CALD1 | caldesmon 1 | -0.033878 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.033806 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0336826 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0336512 |
| RPS24 | ribosomal protein S24 | -0.033412 |
| HDLBP | high density lipoprotein binding protein | -0.0333107 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0332665 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0331776 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0324527 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0321255 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.031367 |
| RPLP1 | ribosomal protein, large, P1 | -0.0310232 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0307036 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0306049 |
| CLTC | clathrin, heavy chain (Hc) | -0.0294678 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0293107 |
| OXR1 | oxidation resistance 1 | -0.0284176 |
| OSMR | oncostatin M receptor | -0.0283733 |
| PGK1 | phosphoglycerate kinase 1 | -0.0280866 |
| COL1A2 | collagen, type I, alpha 2 | -0.028065 |
| NBEAL1 | neurobeachin-like 1 | -0.0280105 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0277628 |
| ANXA2 | annexin A2 | -0.0276451 |
| FNDC3B | fibronectin type III domain containing 3B | -0.027535 |
| MAP4 | microtubule-associated protein 4 | -0.027234 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0271409 |
| SQSTM1 | sequestosome 1 | -0.0270085 |
| H1-0 | H1.0 linker histone | -0.0270057 |
| SEC24D | SEC24 family member D | -0.0268701 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0268608 |
| SEPTIN11 | septin 11 | -0.0268184 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0267845 |
| GNAS | GNAS complex locus | -0.0260375 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0253785 |
| RPS8 | ribosomal protein S8 | -0.0253461 |
| HM13 | histocompatibility (minor) 13 | -0.0252352 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0250547 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.025023 |
| WDR45B | WD repeat domain 45B | -0.0249793 |
| NGLY1 | N-glycanase 1 | -0.0248232 |
| SETD5 | SET domain containing 5 | -0.0247743 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.024695 |
| RAI14 | retinoic acid induced 14 | -0.0245603 |
| S100A9 | S100 calcium binding protein A9 | -0.0245278 |
| MORF4L2 | mortality factor 4 like 2 | -0.024235 |
| RPL38 | ribosomal protein L38 | -0.0241872 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0237401 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0234708 |
| SBF2 | SET binding factor 2 | -0.0230773 |
| TRAM1 | translocation associated membrane protein 1 | -0.0229957 |
| CLINT1 | clathrin interactor 1 | -0.0228224 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0226092 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.022506 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0224504 |
| ADM | adrenomedullin | -0.0220331 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0218835 |
| TMEM263 | transmembrane protein 263 | -0.0217527 |
