ETODOLAC Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A monocarboxylic acid that is acetic acid in which one of the methyl hydrogens is substituted by a 1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-yl moiety. A preferential inhibitor of cyclo-oxygenase 2 and non-steroidal anti-inflammatory, it is used for the treatment of rheumatoid arthritis and osteoarthritis, and for the alleviation of postoperative pain. Administered as the racemate, only the (S)-enantiomer is active. (Chemical Entities of Biological Interest Ontology, CHEBI_4909)
External Link https://dgidb.org/results?searchType=drug&searchTerms=ETODOLAC
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Genes

5 interacting proteins for the ETODOLAC drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.318388
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.211728
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 0.158006
RXRA retinoid X receptor, alpha 0.123098
NFE2L2 nuclear factor, erythroid 2-like 2 0.0125879