ETS1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description v-ets avian erythroblastosis virus E26 oncogene homolog 1|This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 2113)
External Link http://www.ncbi.nlm.nih.gov/gene/2113
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114 interacting proteins for ETS1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARS alanyl-tRNA synthetase
ACAD8 acyl-CoA dehydrogenase family, member 8
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARID4B AT rich interactive domain 4B (RBP1-like)
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4
ATF2 activating transcription factor 2
BRCA1 breast cancer 1, early onset
C17ORF62 chromosome 17 open reading frame 62
C1ORF52 chromosome 1 open reading frame 52
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDC5L cell division cycle 5-like
CENPB centromere protein B, 80kDa
CHMP4A charged multivesicular body protein 4A
CPLX2 complexin 2
CREBBP CREB binding protein
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DAXX death-domain associated protein
EIF3A eukaryotic translation initiation factor 3, subunit A
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF5B eukaryotic translation initiation factor 5B
ELAVL1 ELAV like RNA binding protein 1
ELP2 elongator acetyltransferase complex subunit 2
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPRS glutamyl-prolyl-tRNA synthetase
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM171A1 family with sequence similarity 171, member A1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
GATA3 GATA binding protein 3
GNAS GNAS complex locus
HMGB1 high mobility group box 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IL2RG interleukin 2 receptor, gamma
IL4 interleukin 4
IL4R interleukin 4 receptor
JAK1 Janus kinase 1
JAK3 Janus kinase 3
JUN jun proto-oncogene
JUND jun D proto-oncogene
LAS1L LAS1-like (S. cerevisiae)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MED23 mediator complex subunit 23
MEIS1 Meis homeobox 1
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NEFM neurofilament, medium polypeptide
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOMO2 NODAL modulator 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUCLEOLIN nucleolin multifunctional protein
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PCNX pecanex homolog (Drosophila)
PFDN5 prefoldin subunit 5
PHF14 PHD finger protein 14
PIAS4 protein inhibitor of activated STAT, 4
PLEC plectin
POU1F1 POU class 1 homeobox 1
PPME1 protein phosphatase methylesterase 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAD23B RAD23 homolog B (S. cerevisiae)
RBBP6 retinoblastoma binding protein 6
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RPL13A ribosomal protein L13a
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RUNX2 runt-related transcription factor 2
SCOC short coiled-coil protein
SERBP1 SERPINE1 mRNA binding protein 1
SET SET nuclear proto-oncogene
SLIT2 slit homolog 2 (Drosophila)
SMAD3 SMAD family member 3
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SP1 Sp1 transcription factor
SP100 SP100 nuclear antigen
SPI1 Spi-1 proto-oncogene
SRA1 steroid receptor RNA activator 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF11 serine/arginine-rich splicing factor 11
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUMO2 small ubiquitin-like modifier 2
SV2A synaptic vesicle glycoprotein 2A
TAL1 T-cell acute lymphocytic leukemia 1
TCEAL3 transcription elongation factor A (SII)-like 3
TCF12 transcription factor 12
TCF3 transcription factor 3
TDP2 tyrosyl-DNA phosphodiesterase 2
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TP53 tumor protein p53
TSC1 tuberous sclerosis 1
TTC3 tetratricopeptide repeat domain 3
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
WDR17 WD repeat domain 17
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFR zinc finger RNA binding protein
ZMAT2 zinc finger, matrin-type 2
ZNHIT6 zinc finger, HIT-type containing 6