ETV1 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ets variant 1|This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate many target genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation and differentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing the consensus 5'-CGGA[AT]-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain (TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene is involved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcoma and at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomal rearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 2115)
External Link https://ncbi.nlm.nih.gov/gene/2115
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Genes

496 genes differentially expressed following the ETV1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FAIM Fas apoptotic inhibitory molecule 0.01197
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.00857275
S100A8 S100 calcium binding protein A8 0.00777892
AQP3 aquaporin 3 (Gill blood group) 0.00775537
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00765351
PXDN peroxidasin 0.00761759
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0073339
PRDX2 peroxiredoxin 2 0.00719346
TSPAN13 tetraspanin 13 0.00702934
ABHD4 abhydrolase domain containing 4 0.00700382
ABHD6 abhydrolase domain containing 6 0.00695391
CRABP2 cellular retinoic acid binding protein 2 0.00684769
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00672603
S100A10 S100 calcium binding protein A10 0.00659929
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00648955
DNTT DNA nucleotidylexotransferase 0.00648859
CEMIP cell migration inducing protein, hyaluronan binding 0.00643963
CD200 CD200 molecule 0.00637446
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00634313
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 0.00629331
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00627461
DSP desmoplakin 0.00627279
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00623826
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00623239
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta 0.00621748
NELL2 NEL-like 2 (chicken) 0.00620648
GNAS GNAS complex locus 0.00618835
LXN latexin 0.00618698
KRT19 keratin 19, type I 0.00609044
CXCL12 chemokine (C-X-C motif) ligand 12 0.00602216
PCNA proliferating cell nuclear antigen 0.00587257
LGALS3 lectin, galactoside-binding, soluble, 3 0.00584008
SSBP2 single-stranded DNA binding protein 2 0.0057576
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.00571043
CSTA cystatin A (stefin A) 0.00565362
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.00562659
KRT18 keratin 18, type I 0.00557076
OBSL1 obscurin-like 1 0.00556366
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00555922
SCGB2A2 secretoglobin, family 2A, member 2 0.00549325
RAD23B RAD23 homolog B (S. cerevisiae) 0.00549122
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00542554
EGR2 early growth response 2 0.00526196
CENPE centromere protein E, 312kDa 0.005245
CLDN7 claudin 7 0.00524179
GPX3 glutathione peroxidase 3 0.00520998
PITX1 paired-like homeodomain 1 0.00518368
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00516386
IFITM1 interferon induced transmembrane protein 1 0.00516179
GATA6 GATA binding protein 6 0.00516104
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00511776
IFI16 interferon, gamma-inducible protein 16 0.00509054
ANG angiogenin, ribonuclease, RNase A family, 5 0.00505768
CA4 carbonic anhydrase IV 0.00505625
CALB2 calbindin 2 0.00504964
STK10 serine/threonine kinase 10 0.00500153
CHI3L2 chitinase 3-like 2 0.00499165
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00494557
EDN3 endothelin 3 0.00493355
BAMBI BMP and activin membrane-bound inhibitor 0.00492801
PCLAF PCNA clamp associated factor 0.00488769
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.00488683
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00485569
SEPP1 selenoprotein P, plasma, 1 0.00483275
PRF1 perforin 1 (pore forming protein) 0.0048225
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00481715
CGRRF1 cell growth regulator with ring finger domain 1 0.00480197
ARHGAP44 Rho GTPase activating protein 44 0.00477981
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.00476198
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.00476162
THBS2 thrombospondin 2 0.00475594
GNLY granulysin 0.00474232
FABP4 fatty acid binding protein 4, adipocyte 0.00471827
MPZL2 myelin protein zero-like 2 0.00470387
SYBU syntabulin (syntaxin-interacting) 0.00469485
ADORA2B adenosine A2b receptor 0.00467063
BAALC brain and acute leukemia, cytoplasmic 0.0046518
ABLIM1 actin binding LIM protein 1 0.00465026
SPRR3 small proline-rich protein 3 0.00464391
TNNT1 troponin T type 1 (skeletal, slow) 0.00464185
LRRN3 leucine rich repeat neuronal 3 0.00463994
LMO2 LIM domain only 2 (rhombotin-like 1) 0.00462159
C3 complement component 3 0.00457429
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00456691
SELENBP1 selenium binding protein 1 0.00456193
CEP70 centrosomal protein 70kDa 0.00454939
CLIC5 chloride intracellular channel 5 0.00454724
LAPTM4A lysosomal protein transmembrane 4 alpha 0.00454314
UFM1 ubiquitin-fold modifier 1 0.00454101
ZFP36L2 ZFP36 ring finger protein-like 2 0.00453696
TM4SF1 transmembrane 4 L six family member 1 0.00451414
MCAM melanoma cell adhesion molecule 0.00451309
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.00450257
NEFH neurofilament, heavy polypeptide 0.00449526
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.00447897
LPAR6 lysophosphatidic acid receptor 6 0.00447852
MRPL33 mitochondrial ribosomal protein L33 0.00445689
FHL1 four and a half LIM domains 1 0.00444292
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.00442617
HACD2 3-hydroxyacyl-CoA dehydratase 2 0.00441281
EXT1 exostosin glycosyltransferase 1 0.00438305
PDIA6 protein disulfide isomerase family A, member 6 0.0043822
EIF5A eukaryotic translation initiation factor 5A 0.00437085
CLCA4 chloride channel accessory 4 0.00432551
CCK cholecystokinin 0.00431755
SELL selectin L 0.00431371
IL32 interleukin 32 0.00430269
PDIA3 protein disulfide isomerase family A, member 3 0.00429441
HSPA1A heat shock 70kDa protein 1A 0.0042892
SLPI secretory leukocyte peptidase inhibitor 0.0042802
TFRC transferrin receptor 0.00427855
SSR4 signal sequence receptor, delta 0.00427297
NEK7 NIMA-related kinase 7 0.00426921
OPN3 opsin 3 0.00426862
CRYAB crystallin, alpha B 0.00426685
OXTR oxytocin receptor 0.00424838
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.00424588
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.00423544
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00422814
PI3 peptidase inhibitor 3, skin-derived 0.00421854
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.0042166
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.00416141
G0S2 G0/G1 switch 2 0.00414643
SLC35G2 solute carrier family 35, member G2 0.00412269
FKBP5 FK506 binding protein 5 0.00412078
SEZ6L2 seizure related 6 homolog (mouse)-like 2 0.00411673
CHGB chromogranin B 0.00411114
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.00410307
DDR2 discoidin domain receptor tyrosine kinase 2 0.00409399
GREB1 growth regulation by estrogen in breast cancer 1 0.0040766
SPON1 spondin 1, extracellular matrix protein 0.004067
PLIN2 perilipin 2 0.00406265
NPY1R neuropeptide Y receptor Y1 0.00405943
CCN2 cellular communication network factor 2 0.00405723
CLTB clathrin, light chain B 0.00405234
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 0.00404246
STOM stomatin 0.00404241
NR2F2 nuclear receptor subfamily 2, group F, member 2 0.0040409
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.00403588
PF4 platelet factor 4 0.0040357
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0040203
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.00401097
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00400976
CFI complement factor I 0.00400857
RAB21 RAB21, member RAS oncogene family 0.00400643
MAOB monoamine oxidase B 0.00399441
KRT14 keratin 14, type I 0.00399136
NRN1 neuritin 1 0.00399071
TYROBP TYRO protein tyrosine kinase binding protein 0.00398475
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.00398415
RNASET2 ribonuclease T2 0.00398358
KLK6 kallikrein-related peptidase 6 0.00396861
OSBPL8 oxysterol binding protein-like 8 0.00394606
ANXA2 annexin A2 0.00394365
VLDLR very low density lipoprotein receptor 0.00392605
ADIRF adipogenesis regulatory factor 0.00390457
PAX5 paired box 5 0.00390326
MCOLN1 mucolipin 1 0.00390084
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00389774
CCNG1 cyclin G1 0.00388282
BPIFA1 BPI fold containing family A, member 1 0.00388109
XIC X chromosome inactivation center 0.0038762
RTN1 reticulon 1 0.00386183
CXCL13 chemokine (C-X-C motif) ligand 13 0.00385987
CSF1R colony stimulating factor 1 receptor 0.00385616
RGS4 regulator of G-protein signaling 4 0.00385074
HBD hemoglobin, delta 0.00384912
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00382894
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00381648
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00381547
HBEGF heparin-binding EGF-like growth factor 0.00381444
PLA2G12A phospholipase A2, group XIIA 0.00380227
ADCY7 adenylate cyclase 7 0.0038001
GJA1 gap junction protein, alpha 1, 43kDa 0.0037896
EIF5B eukaryotic translation initiation factor 5B 0.00378696
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.00377946
NUSAP1 nucleolar and spindle associated protein 1 0.00377379
CLDN8 claudin 8 0.00376342
RELN reelin 0.00374075
MEG3 maternally expressed 3 (non-protein coding) 0.00373982
CLCA1 chloride channel accessory 1 0.00373653
HSPA12A heat shock 70kDa protein 12A 0.00372812
NSG1 neuron specific gene family member 1 0.00372761
C6ORF62 chromosome 6 open reading frame 62 0.00371712
LUM lumican 0.00371513
S100A14 S100 calcium binding protein A14 0.00368567
ADA adenosine deaminase 0.00368211
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.00367436
RLN2 relaxin 2 0.00367116
ACAA2 acetyl-CoA acyltransferase 2 0.003668
JUND jun D proto-oncogene 0.00366538
SH3GL3 SH3-domain GRB2-like 3 0.00366506
TIMP1 TIMP metallopeptidase inhibitor 1 0.00366276
ADGRG2 adhesion G protein-coupled receptor G2 0.00365739
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 0.003651
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.00364809
STAB1 stabilin 1 0.00364343
STMN2 stathmin 2 0.00363836
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 0.00363655
GMFB glia maturation factor, beta 0.00363379
TOX thymocyte selection-associated high mobility group box 0.00363304
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.0036294
COL6A1 collagen, type VI, alpha 1 0.00362651
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.00362149
AMPH amphiphysin 0.003618
KLHDC8A kelch domain containing 8A 0.00360011
RALGDS ral guanine nucleotide dissociation stimulator 0.00359973
ZG16 zymogen granule protein 16 0.00359939
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00358888
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.00358126
TUBA1A tubulin, alpha 1a 0.00358105
VCAN versican 0.00358037
AQP1 aquaporin 1 (Colton blood group) 0.0035768
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.00355619
GDI2 GDP dissociation inhibitor 2 0.00354984
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0035491
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.00354515
MAN2A1 mannosidase, alpha, class 2A, member 1 0.00354126
LMCD1 LIM and cysteine-rich domains 1 0.00353729
CCNB1 cyclin B1 0.00351626
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00351575
FASN fatty acid synthase 0.00350844
TCTA T-cell leukemia translocation altered 0.0035
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00349905
SOX10 SRY (sex determining region Y)-box 10 0.00349118
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 0.00348509
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.00347929
NAP1L1 nucleosome assembly protein 1-like 1 0.00347393
NMU neuromedin U 0.00346836
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.00345944
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 0.0034569
KRT23 keratin 23, type I 0.00345325
RGL1 ral guanine nucleotide dissociation stimulator-like 1 0.00344688
PXMP2 peroxisomal membrane protein 2, 22kDa 0.0034442
GSTA4 glutathione S-transferase alpha 4 0.00342634
NDRG2 NDRG family member 2 0.00342257
SPINK4 serine peptidase inhibitor, Kazal type 4 0.00342131
KDSR 3-ketodihydrosphingosine reductase 0.00341885
ANXA1 annexin A1 0.00341631
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00341467
XYLT1 xylosyltransferase I 0.00341306
SDF2L1 stromal cell-derived factor 2-like 1 0.00341154
MYT1L myelin transcription factor 1-like 0.00340729
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.00340552
TMED7 transmembrane emp24 protein transport domain containing 7 0.00340358
FZD4 frizzled class receptor 4 0.00340225
BLVRB biliverdin reductase B 0.00340162
EIF4B eukaryotic translation initiation factor 4B 0.00340057
CA12 carbonic anhydrase XII 0.00339576
MYH10 myosin, heavy chain 10, non-muscle 0.0033907

decreased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 -0.0101862
HIST1H2BK histone cluster 1, H2bk -0.00921773
MAGEA3 melanoma antigen family A3 -0.00794177
PFKL phosphofructokinase, liver -0.00778977
IDO1 indoleamine 2,3-dioxygenase 1 -0.00763527
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00700314
CXCL9 chemokine (C-X-C motif) ligand 9 -0.00695986
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00689881
FAM13A family with sequence similarity 13, member A -0.00679184
ETV1 ets variant 1 -0.00640754
TPSAB1 tryptase alpha/beta 1 -0.00630596
DYNLL1 dynein, light chain, LC8-type 1 -0.00618704
THY1 Thy-1 cell surface antigen -0.00608951
MAP7 microtubule-associated protein 7 -0.00594835
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00585956
CLGN calmegin -0.0057251
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00555898
SPRED2 sprouty-related, EVH1 domain containing 2 -0.00555551
ALDOB aldolase B, fructose-bisphosphate -0.00555468
HMG20B high mobility group 20B -0.00555385
PLAU plasminogen activator, urokinase -0.00552506
GATA2 GATA binding protein 2 -0.0055206
FBN2 fibrillin 2 -0.0055168
ANO1 anoctamin 1, calcium activated chloride channel -0.00543739
FGFR3 fibroblast growth factor receptor 3 -0.00539127
MAGEA12 melanoma antigen family A12 -0.00531678
MYB v-myb avian myeloblastosis viral oncogene homolog -0.00528659
TOX3 TOX high mobility group box family member 3 -0.00520604
COL9A2 collagen, type IX, alpha 2 -0.00517762
CPVL carboxypeptidase, vitellogenic-like -0.00513791
GPX2 glutathione peroxidase 2 -0.00502302
S100P S100 calcium binding protein P -0.00501856
DMXL2 Dmx-like 2 -0.0049461
SPRY2 sprouty homolog 2 (Drosophila) -0.00489437
PLAT plasminogen activator, tissue -0.00489067
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.00488758
BCHE butyrylcholinesterase -0.00488145
PLPP3 phospholipid phosphatase 3 -0.00480722
RABGAP1L RAB GTPase activating protein 1-like -0.0047844
MYH11 myosin, heavy chain 11, smooth muscle -0.00471744
CRISP3 cysteine-rich secretory protein 3 -0.00471444
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00469999
ACSM3 acyl-CoA synthetase medium-chain family member 3 -0.00467323
PPAP2A phosphatidic acid phosphatase type 2A -0.00466312
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00464466
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00463641
RC3H2 ring finger and CCCH-type domains 2 -0.00463179
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00461664
PBX3 pre-B-cell leukemia homeobox 3 -0.00458535
AZU1 azurocidin 1 -0.00457404
DUSP5 dual specificity phosphatase 5 -0.00452421
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00452237
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 -0.00452039
LRRC17 leucine rich repeat containing 17 -0.00451339
EMP3 epithelial membrane protein 3 -0.00449849
PRTN3 proteinase 3 -0.00448874
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.00447253
TSPAN8 tetraspanin 8 -0.0044399
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.0044349
NAV3 neuron navigator 3 -0.00443402
LYN LYN proto-oncogene, Src family tyrosine kinase -0.00440693
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.00440074
RAB38 RAB38, member RAS oncogene family -0.00437887
CD38 CD38 molecule -0.00437386
DGKD diacylglycerol kinase, delta 130kDa -0.00435407
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00434758
RTN3 reticulon 3 -0.00432622
CPA3 carboxypeptidase A3 (mast cell) -0.00431749
NANOG Nanog homeobox -0.00430871
IDE insulin-degrading enzyme -0.00427612
TYRP1 tyrosinase-related protein 1 -0.00427607
GSTM3 glutathione S-transferase mu 3 (brain) -0.00425968
CRYM crystallin, mu -0.00425061
BTG1 B-cell translocation gene 1, anti-proliferative -0.00420808
MGLL monoglyceride lipase -0.00420469
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) -0.00419798
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 -0.00418797
ELANE elastase, neutrophil expressed -0.00416414
EFNB2 ephrin-B2 -0.00414957
KYNU kynureninase -0.00411344
ARG1 arginase 1 -0.00410924
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.00408748
ALCAM activated leukocyte cell adhesion molecule -0.00407827
CD9 CD9 molecule -0.00405467
HIST1H2BD histone cluster 1, H2bd -0.00405023
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 -0.00399885
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00399465
DGLUCY D-glutamate cyclase -0.00398164
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1 -0.00395741
IRS1 insulin receptor substrate 1 -0.00394776
MMP12 matrix metallopeptidase 12 -0.00394751
CCP110 centriolar coiled coil protein 110kDa -0.00393107
CTSK cathepsin K -0.00388547
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -0.00387163
CTBP2 C-terminal binding protein 2 -0.00386355
HIST1H2BH histone cluster 1, H2bh -0.00386039
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00385989
STC1 stanniocalcin 1 -0.00385812
ITGB4 integrin, beta 4 -0.00385436
GREM1 gremlin 1, DAN family BMP antagonist -0.00384454
DSC1 desmocollin 1 -0.00382566
THAP9-AS1 THAP9 antisense RNA 1 -0.00381715
HLA-DMB major histocompatibility complex, class II, DM beta -0.00379578
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -0.0037931
TMC5 transmembrane channel-like 5 -0.00378064
ADAM9 ADAM metallopeptidase domain 9 -0.00378019
PDGFRL platelet-derived growth factor receptor-like -0.00377045
SEC16A SEC16 homolog A (S. cerevisiae) -0.00375431
CD44 CD44 molecule (Indian blood group) -0.00374797
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00374662
FAM117A family with sequence similarity 117, member A -0.00374412
BTBD3 BTB (POZ) domain containing 3 -0.00373755
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.00373063
DEPTOR DEP domain containing MTOR-interacting protein -0.00373024
SLIT2 slit homolog 2 (Drosophila) -0.00373011
GSTA1 glutathione S-transferase alpha 1 -0.00372825
PDE10A phosphodiesterase 10A -0.00371428
GPR88 G protein-coupled receptor 88 -0.00370646
BIRC3 baculoviral IAP repeat containing 3 -0.00370048
DUSP10 dual specificity phosphatase 10 -0.00369764
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.00368991
MMP13 matrix metallopeptidase 13 -0.00367693
ACTG2 actin, gamma 2, smooth muscle, enteric -0.00367454
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -0.00367255
TNS3 tensin 3 -0.00366941
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 -0.00366622
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 -0.00365775
FRY furry homolog (Drosophila) -0.00364138
BCL2A1 BCL2-related protein A1 -0.0036389
MNAT1 MNAT CDK-activating kinase assembly factor 1 -0.00363786
PIPOX pipecolic acid oxidase -0.00363309
PSD3 pleckstrin and Sec7 domain containing 3 -0.00363248
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00362703
FGL1 fibrinogen-like 1 -0.00362636
COL15A1 collagen, type XV, alpha 1 -0.00362234
DIAPH2 diaphanous-related formin 2 -0.00361047
FOLR1 folate receptor 1 (adult) -0.00360924
PEG10 paternally expressed 10 -0.00359709
C4BPA complement component 4 binding protein, alpha -0.00358898
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.0035888
AKAP8 A kinase (PRKA) anchor protein 8 -0.00358566
JUP junction plakoglobin -0.00358153
CLC Charcot-Leyden crystal galectin -0.00356343
FBN1 fibrillin 1 -0.0035623
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.00355673
SCG5 secretogranin V -0.00354947
TDO2 tryptophan 2,3-dioxygenase -0.00353986
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.00353664
ATF3 activating transcription factor 3 -0.00353595
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00351702
SOX13 SRY (sex determining region Y)-box 13 -0.00351096
MICALL1 MICAL-like 1 -0.00350635
EML1 echinoderm microtubule associated protein like 1 -0.00350365
DPF2 D4, zinc and double PHD fingers family 2 -0.00350271
CCND1 cyclin D1 -0.0035027
MMP1 matrix metallopeptidase 1 -0.00350035
SOCS1 suppressor of cytokine signaling 1 -0.00348194
EFHC1 EF-hand domain (C-terminal) containing 1 -0.00348103
RNF19B ring finger protein 19B -0.0034777
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog -0.00347731
STK26 serine/threonine protein kinase 26 -0.00346804
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00344782
SPAG9 sperm associated antigen 9 -0.00344607
LAMA5 laminin, alpha 5 -0.00344072
GARS1 glycyl-tRNA synthetase 1 -0.00343866
COL4A5 collagen, type IV, alpha 5 -0.00343648
HIPK3 homeodomain interacting protein kinase 3 -0.00343487
PPIE peptidylprolyl isomerase E (cyclophilin E) -0.00343208
TMEM47 transmembrane protein 47 -0.00343183
HIP1 huntingtin interacting protein 1 -0.00342872
PFKM phosphofructokinase, muscle -0.00342238
KLF5 Kruppel-like factor 5 (intestinal) -0.00341765
FOLH1B folate hydrolase 1B -0.00341618
TSPYL5 TSPY-like 5 -0.00341437
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 -0.00340538
MPHOSPH6 M-phase phosphoprotein 6 -0.00339204
PMP22 peripheral myelin protein 22 -0.00338882
PTPRD protein tyrosine phosphatase, receptor type, D -0.00338272
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.0033794
TPTE transmembrane phosphatase with tensin homology -0.00337763
NCDN neurochondrin -0.00337182
DPT dermatopontin -0.0033594
ZEB1 zinc finger E-box binding homeobox 1 -0.00335201
IFI44L interferon-induced protein 44-like -0.00334887
IPO13 importin 13 -0.00334831
MET MET proto-oncogene, receptor tyrosine kinase -0.0033349
SSX1 synovial sarcoma, X breakpoint 1 -0.00332082
SETD5 SET domain containing 5 -0.00332024
EAF2 ELL associated factor 2 -0.00331725
MGAM maltase-glucoamylase -0.00331091
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2 -0.00330983
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae) -0.00330789
GSDMB gasdermin B -0.00330479
GEM GTP binding protein overexpressed in skeletal muscle -0.00328513
HDAC9 histone deacetylase 9 -0.00327198
MACROD1 MACRO domain containing 1 -0.00327115
CCDC92 coiled-coil domain containing 92 -0.00326346
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00326087
PRUNE2 prune homolog 2 (Drosophila) -0.00325767
HABP2 hyaluronan binding protein 2 -0.00325737
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.00325729
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00325132
TFF3 trefoil factor 3 (intestinal) -0.00324044
BID BH3 interacting domain death agonist -0.00323769
BNC2 basonuclin 2 -0.00323729
SAV1 salvador family WW domain containing protein 1 -0.00322806
GATA3 GATA binding protein 3 -0.00322459
C21ORF91 chromosome 21 open reading frame 91 -0.00322215
GTPBP1 GTP binding protein 1 -0.00322066
CADM1 cell adhesion molecule 1 -0.00321909
PER1 period circadian clock 1 -0.0032188
RGS16 regulator of G-protein signaling 16 -0.00321728
PLXNB2 plexin B2 -0.00321108
DNMBP dynamin binding protein -0.00320749
ARL4A ADP-ribosylation factor-like 4A -0.0031953
NXF3 nuclear RNA export factor 3 -0.00319161
PUDP pseudouridine 5'-phosphatase -0.00318969
CDK14 cyclin-dependent kinase 14 -0.00318269
TSPAN12 tetraspanin 12 -0.0031798
NAXD NAD(P)HX dehydratase -0.00317094
RNPS1 RNA binding protein S1, serine-rich domain -0.00316007
PRKCSH protein kinase C substrate 80K-H -0.00315806
TPPP3 tubulin polymerization-promoting protein family member 3 -0.00315496
PLXDC1 plexin domain containing 1 -0.0031474
TTC17 tetratricopeptide repeat domain 17 -0.00314422
FTH1 ferritin, heavy polypeptide 1 -0.00314251
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase -0.00314181
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.00313981
SLC43A3 solute carrier family 43, member 3 -0.00313633
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 -0.00313374
SMTN smoothelin -0.00313353
PSAT1 phosphoserine aminotransferase 1 -0.003127
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.00312589
DAPK1 death-associated protein kinase 1 -0.00311838
KLF9 Kruppel-like factor 9 -0.00311319
FOXF1 forkhead box F1 -0.00311279
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00311181
PHIP pleckstrin homology domain interacting protein -0.00310994
SIX1 SIX homeobox 1 -0.00310958
HK1 hexokinase 1 -0.00310367
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound -0.00309122
ENO3 enolase 3 (beta, muscle) -0.00308694
HMGN3 high mobility group nucleosomal binding domain 3 -0.00307596
ANXA10 annexin A10 -0.00307578
AUTS2 autism susceptibility candidate 2 -0.00307483
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00306386