EVX1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description even-skipped homeobox 1|This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded protein may play an important role as a transcriptional repressor during embryogenesis. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2128)
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Genes

350 genes differentially expressed following the EVX1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PCDHA6 protocadherin alpha 6 3.16297
UNC13C unc-13 homolog C (C. elegans) 3.16297
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.16297
TKTL1 transketolase-like 1 3.16297
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 3.16297
GFAP glial fibrillary acidic protein 3.16297
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 3.16297
SIGLEC7 sialic acid binding Ig-like lectin 7 3.16297
LRG1 leucine-rich alpha-2-glycoprotein 1 3.16297
RSPO1 R-spondin 1 3.16297
DPEP2 dipeptidase 2 3.16297
HES4 hes family bHLH transcription factor 4 3.16297
OR1A1 olfactory receptor, family 1, subfamily A, member 1 3.16297
IL12RB1 interleukin 12 receptor, beta 1 3.16297
FAM170A family with sequence similarity 170, member A 3.16297
HHEX hematopoietically expressed homeobox 3.16297
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 3.16297
INHBB inhibin, beta B 3.16297
NAPSA napsin A aspartic peptidase 3.16297
FBXL8 F-box and leucine-rich repeat protein 8 3.16297
SPINK4 serine peptidase inhibitor, Kazal type 4 3.16297
PDIA2 protein disulfide isomerase family A, member 2 3.16297
NEU4 sialidase 4 3.16297
CCL3L3 chemokine (C-C motif) ligand 3-like 3 3.16297
MFAP5 microfibrillar associated protein 5 3.16297
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) 3.16297
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.16297
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 3.16297
CFAP58 cilia and flagella associated protein 58 3.16297
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22 3.16297
LEP leptin 3.16297
IL23R interleukin 23 receptor 3.16297
OR4E2 olfactory receptor, family 4, subfamily E, member 2 3.16297
PPP1R3A protein phosphatase 1, regulatory subunit 3A 3.16297
HBM hemoglobin, mu 3.16297
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative) 3.16297
SPINK13 serine peptidase inhibitor, Kazal type 13 (putative) 3.16297
GPR21 G protein-coupled receptor 21 3.16297
SP7 Sp7 transcription factor 3.16297
OTUD6A OTU deubiquitinase 6A 3.16297
GADL1 glutamate decarboxylase-like 1 3.16297
CD163 CD163 molecule 3.16297
PSCA prostate stem cell antigen 3.16297
CCDC38 coiled-coil domain containing 38 3.16297
LRRIQ4 leucine-rich repeats and IQ motif containing 4 3.16297
TMEM121 transmembrane protein 121 3.16297
PADI1 peptidyl arginine deiminase, type I 3.16297
OASL 2'-5'-oligoadenylate synthetase-like 3.16297
SPMIP6 sperm microtubule inner protein 6 3.16297
ERVW-1 endogenous retrovirus group W, member 1 3.16297
GBP3 guanylate binding protein 3 3.16297
ROPN1B rhophilin associated tail protein 1B 3.16297
GPX6 glutathione peroxidase 6 3.16297
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 3.16297
MGAT4D MGAT4 family, member D 3.16297
STMN4 stathmin-like 4 3.16297
FIMP1 fertilization-influencing membrane protein 1 3.16297
FMO2 flavin containing monooxygenase 2 (non-functional) 3.16297
ANGPTL8 angiopoietin like 8 3.16297
ASDURF ASNSD1 upstream open reading frame 3.16297
SMIM36 small integral membrane protein 36 3.16297
DUSP13B dual specificity phosphatase 13B 3.16297
NHERF4 NHERF family PDZ scaffold protein 4 3.16297
H3C13 H3 clustered histone 13 3.16297
H4C12 H4 clustered histone 12 3.16297
H4C14 H4 clustered histone 14 3.16297
MUCL3 mucin like 3 3.16297
CFAP276 cilia and flagella associated protein 276 3.16297
MEIOSIN meiosis initiator 3.16297
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.16297
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 3.16297
TFF2 trefoil factor 2 3.16297
BDKRB2 bradykinin receptor B2 3.16297
UTS2 urotensin 2 3.16297
PGLYRP2 peptidoglycan recognition protein 2 3.16297
SBSN suprabasin 3.16297
TFEC transcription factor EC 3.16297
SCYL1 SCY1-like 1 (S. cerevisiae) 3.16297
ZIC4 Zic family member 4 3.16297
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.16297
TMEM235 transmembrane protein 235 3.16297
SLC22A25 solute carrier family 22, member 25 3.16297
ALG10B ALG10B, alpha-1,2-glucosyltransferase 3.16297
TIMD4 T-cell immunoglobulin and mucin domain containing 4 3.16297
FRK fyn-related Src family tyrosine kinase 3.16297
XKR3 XK, Kell blood group complex subunit-related family, member 3 3.16297
LY6K lymphocyte antigen 6 complex, locus K 3.16297
TBX10 T-box 10 3.16297
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 3.16297
CNTN3 contactin 3 (plasmacytoma associated) 3.16297
ASIC4 acid sensing (proton gated) ion channel family member 4 3.16297
LRRC73 leucine rich repeat containing 73 3.16297
LRRC72 leucine rich repeat containing 72 3.16297
LRRC70 leucine rich repeat containing 70 3.16297
CLDN2 claudin 2 3.16297
CLRN1 clarin 1 3.16297
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 3.16297
MR1 major histocompatibility complex, class I-related 3.16297
NIM1K NIM1 serine/threonine protein kinase 3.16297
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.16297
KLK11 kallikrein-related peptidase 11 3.16297
MYF5 myogenic factor 5 3.16297
MYF6 myogenic factor 6 (herculin) 3.16297
KRT1 keratin 1, type II 3.16297
EGR2 early growth response 2 3.16297
NTF4 neurotrophin 4 3.16297
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 3.16297
ZNF366 zinc finger protein 366 3.16297
VAX2 ventral anterior homeobox 2 3.16297
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.16297
APOD apolipoprotein D 3.16297
HYLS1 hydrolethalus syndrome 1 3.16297
LY96 lymphocyte antigen 96 3.16297
HOPX HOP homeobox 3.16297
DHH desert hedgehog 3.16297
TAS2R50 taste receptor, type 2, member 50 3.16297
ARR3 arrestin 3, retinal (X-arrestin) 3.16297
S100A14 S100 calcium binding protein A14 3.16297
MAMDC4 MAM domain containing 4 3.16297
SERPINB11 serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) 3.16297
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.16297
EFCAB3 EF-hand calcium binding domain 3 3.16297
KLF1 Kruppel-like factor 1 (erythroid) 3.16297
CERKL ceramide kinase-like 3.16297
CTAGE15 CTAGE family, member 15 3.16297
ODF4 outer dense fiber of sperm tails 4 3.16297
OR56A3 olfactory receptor, family 56, subfamily A, member 3 3.16297
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 3.16297
DRD5 dopamine receptor D5 3.16297
CDHR5 cadherin-related family member 5 3.16297
C2CD4B C2 calcium-dependent domain containing 4B 3.16297
CCL15 chemokine (C-C motif) ligand 15 3.16297
GFRAL GDNF family receptor alpha like 3.16297
SDSL serine dehydratase-like 3.16297
LAMP5 lysosomal-associated membrane protein family, member 5 3.16297
GPR50 G protein-coupled receptor 50 3.16297
CSNK1A1L casein kinase 1, alpha 1-like 3.16297
TMPRSS15 transmembrane protease, serine 15 3.16297
ZBED6 zinc finger, BED-type containing 6 3.16297
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 3.16297
SLCO1C1 solute carrier organic anion transporter family, member 1C1 3.16297
GPR149 G protein-coupled receptor 149 3.16297
MEIS1 Meis homeobox 1 3.16297
GOLGA8J golgin A8 family, member J 3.16297
TGM5 transglutaminase 5 3.16297
TGM6 transglutaminase 6 3.16297
LY6G6C lymphocyte antigen 6 complex, locus G6C 3.16297
SIDT1 SID1 transmembrane family, member 1 3.16297
TGM7 transglutaminase 7 3.16297
APOL1 apolipoprotein L, 1 3.16297
VCAM1 vascular cell adhesion molecule 1 3.16297
INSL4 insulin-like 4 (placenta) 3.16297
PRR15L proline rich 15-like 3.16297
GPR61 G protein-coupled receptor 61 3.16297
OR14J1 olfactory receptor, family 14, subfamily J, member 1 3.16297
TBC1D26 TBC1 domain family, member 26 3.16297
TOPAZ1 testis and ovary specific PAZ domain containing 1 3.16297
TSPAN32 tetraspanin 32 3.16297
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 3.16297
NTN5 netrin 5 3.16297
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 3.16297
DAND5 DAN domain family member 5, BMP antagonist 3.16297
POTEC POTE ankyrin domain family, member C 3.16297
SLC7A4 solute carrier family 7, member 4 3.16297
RGS8 regulator of G-protein signaling 8 3.16297
DCN decorin 3.16297
PENK proenkephalin 3.16297
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 3.104
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 3.07591
TLR2 toll-like receptor 2 3.07591
FBXL19 F-box and leucine-rich repeat protein 19 2.99797
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.98207
EI24 etoposide induced 2.4 2.87479
NRL neural retina leucine zipper 2.86715
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 2.74054
PRMT8 protein arginine methyltransferase 8 2.69079
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.62054
HLA-DRA major histocompatibility complex, class II, DR alpha 2.59815
RPL14 ribosomal protein L14 2.59792
PLEKHM3 pleckstrin homology domain containing, family M, member 3 2.59542
NOPCHAP1 NOP protein chaperone 1 2.59336
CENPH centromere protein H 2.51634
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.50819
PGAM5 phosphoglycerate mutase family member 5 2.4609
NLRP10 NLR family, pyrin domain containing 10 2.45839
CDH10 cadherin 10, type 2 (T2-cadherin) 2.45398
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 2.42697
CCDC74B coiled-coil domain containing 74B 2.40471
PLEKHD1 pleckstrin homology domain containing, family D (with coiled-coil domains) member 1 2.38517
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.38393
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like 2.3834
SUMO1 small ubiquitin-like modifier 1 2.38118
TYW2 tRNA wybutosine-synthesizing protein 2 2.36853
SLC25A44 solute carrier family 25, member 44 2.36288
ANG angiogenin, ribonuclease, RNase A family, 5 2.34307
LYPD6 LY6/PLAUR domain containing 6 2.3428
COMMD4 COMM domain containing 4 2.34125
CISD3 CDGSH iron sulfur domain 3 2.31931
GPR161 G protein-coupled receptor 161 2.31055
ANAPC11 anaphase promoting complex subunit 11 2.30699
OTOA otoancorin 2.30699
SLC39A4 solute carrier family 39 (zinc transporter), member 4 2.27707
LRR1 leucine rich repeat protein 1 2.27707
PEPD peptidase D 2.2405
EFNA2 ephrin-A2 2.22044
TMCC3 transmembrane and coiled-coil domain family 3 2.21556
RPS15 ribosomal protein S15 2.20291
COG3 component of oligomeric golgi complex 3 2.19048
WDFY2 WD repeat and FYVE domain containing 2 2.18338
PRELID1 PRELI domain containing 1 2.18338
GCAT glycine C-acetyltransferase 2.1767
FAM124B family with sequence similarity 124B 2.17057
GAMT guanidinoacetate N-methyltransferase 2.16673
PRPF39 pre-mRNA processing factor 39 2.16673
PPP1R15A protein phosphatase 1, regulatory subunit 15A 2.15367
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.15076
TTI1 TELO2 interacting protein 1 2.14369
RPS21 ribosomal protein S21 2.13647
FDXR ferredoxin reductase 2.135
PBX4 pre-B-cell leukemia homeobox 4 2.13357
NOTCH3 notch 3 2.12982
TSGA10IP testis specific, 10 interacting protein 2.12982
PLEK2 pleckstrin 2 2.12982
NXPH3 neurexophilin 3 2.12982
C1ORF116 chromosome 1 open reading frame 116 2.12982
SMIM3 small integral membrane protein 3 2.12982
FTL ferritin, light polypeptide 2.12982
ACSBG2 acyl-CoA synthetase bubblegum family member 2 2.12982
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.12982
MSTO1 misato 1, mitochondrial distribution and morphology regulator 2.12982
FAM171B family with sequence similarity 171, member B 2.11528
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.10661
TENT5C terminal nucleotidyltransferase 5C 2.0972
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 2.0686
GXYLT1 glucoside xylosyltransferase 1 2.06751
FKBPL FK506 binding protein like 2.06416
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 2.06416
TUBB6 tubulin, beta 6 class V 2.06001
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 2.0539
ZDHHC1 zinc finger, DHHC-type containing 1 2.0506
TBPL1 TBP-like 1 2.02771
ABHD14A abhydrolase domain containing 14A 2.00798

decreased expression

Symbol Name Standardized Value
GYPE glycophorin E (MNS blood group) -3.16297
PCDHB4 protocadherin beta 4 -3.16297
HCST hematopoietic cell signal transducer -3.16297
FPR1 formyl peptide receptor 1 -3.16297
HYKK hydroxylysine kinase -3.16297
FPR2 formyl peptide receptor 2 -3.16297
EFHB EF-hand domain family, member B -3.16297
IL31RA interleukin 31 receptor A -3.16297
FADS6 fatty acid desaturase 6 -3.16297
NAT16 N-acetyltransferase 16 (GCN5-related, putative) -3.16297
PRSS35 protease, serine, 35 -3.16297
ACRBP acrosin binding protein -3.16297
HIGD1C HIG1 hypoxia inducible domain family, member 1C -3.16297
LIPH lipase, member H -3.16297
RSPH1 radial spoke head 1 homolog (Chlamydomonas) -3.16297
CLEC14A C-type lectin domain family 14, member A -3.16297
RAI2 retinoic acid induced 2 -3.16297
SLC5A9 solute carrier family 5 (sodium/sugar cotransporter), member 9 -3.16297
LIN54 lin-54 DREAM MuvB core complex component -3.16297
CD79A CD79a molecule, immunoglobulin-associated alpha -3.16297
RUNDC3A RUN domain containing 3A -3.16297
THOP1 thimet oligopeptidase 1 -3.16297
NPIPB12 nuclear pore complex interacting protein family member B12 -3.16297
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 -3.16297
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A -3.16297
INSYN1 inhibitory synaptic factor 1 -3.16297
RBBP8NL RBBP8 N-terminal like -3.16297
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -3.16297
MESP1 mesoderm posterior basic helix-loop-helix transcription factor 1 -3.16297
ZFP92 ZFP92 zinc finger protein -3.16297
TMPRSS7 transmembrane protease, serine 7 -3.16297
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 -3.16297
HAPLN2 hyaluronan and proteoglycan link protein 2 -3.16297
FAM186B family with sequence similarity 186, member B -3.16297
HAL histidine ammonia-lyase -3.16297
FBXO4 F-box protein 4 -3.16297
IL5RA interleukin 5 receptor, alpha -3.16297
REP15 RAB15 effector protein -3.16297
FBXL22 F-box and leucine-rich repeat protein 22 -3.05118
TNC tenascin C -3.0213
RRP36 ribosomal RNA processing 36 homolog (S. cerevisiae) -2.86795
TNNC1 troponin C type 1 (slow) -2.81494
RAB27B RAB27B, member RAS oncogene family -2.77628
CTRL chymotrypsin-like -2.77563
GRHL2 grainyhead-like 2 (Drosophila) -2.73756
KIFAP3 kinesin-associated protein 3 -2.62671
TRDMT1 tRNA aspartic acid methyltransferase 1 -2.59815
AMPD3 adenosine monophosphate deaminase 3 -2.56695
ZSCAN32 zinc finger and SCAN domain containing 32 -2.55756
CDC14A cell division cycle 14A -2.54474
CCDC183 coiled-coil domain containing 183 -2.53123
FAM222A family with sequence similarity 222, member A -2.51089
APCDD1 adenomatosis polyposis coli down-regulated 1 -2.51089
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -2.5029
RNF212 ring finger protein 212 -2.46798
ING5 inhibitor of growth family, member 5 -2.46661
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) -2.46027
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -2.46027
PTPN11 protein tyrosine phosphatase, non-receptor type 11 -2.41009
ABAT 4-aminobutyrate aminotransferase -2.41009
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -2.39977
ZNF143 zinc finger protein 143 -2.3962
RMP64 ribonuclease MRP subunit p64 -2.39236
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like) -2.38813
AP3B2 adaptor-related protein complex 3, beta 2 subunit -2.37812
AADAT aminoadipate aminotransferase -2.36956
EGLN2 egl-9 family hypoxia-inducible factor 2 -2.32558
SCIMP SLP adaptor and CSK interacting membrane protein -2.31242
CKAP4 cytoskeleton-associated protein 4 -2.30699
TPD52L1 tumor protein D52-like 1 -2.29173
MRPL55 mitochondrial ribosomal protein L55 -2.27872
SLC4A10 solute carrier family 4, sodium bicarbonate transporter, member 10 -2.23911
ATP2A3 ATPase, Ca++ transporting, ubiquitous -2.23892
H2AC7 H2A clustered histone 7 -2.23848
PFKM phosphofructokinase, muscle -2.23004
PCDHB2 protocadherin beta 2 -2.1883
TTLL10 tubulin tyrosine ligase-like family member 10 -2.18366
FER fer (fps/fes related) tyrosine kinase -2.18338
TMEM120B transmembrane protein 120B -2.16841
PTPRG protein tyrosine phosphatase, receptor type, G -2.15533
TCP10L t-complex 10-like -2.15367
EMC10 ER membrane protein complex subunit 10 -2.14522
POLR3H polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) -2.12982
KDM5B lysine (K)-specific demethylase 5B -2.12982
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1 -2.12982
OCRL oculocerebrorenal syndrome of Lowe -2.12627
NUP153 nucleoporin 153kDa -2.12501
COX17 COX17 cytochrome c oxidase copper chaperone -2.12366
TMEM190 transmembrane protein 190 -2.1176
DNAH8 dynein, axonemal, heavy chain 8 -2.1176
ANAPC4 anaphase promoting complex subunit 4 -2.11528
GOLT1B golgi transport 1B -2.11528
CDH7 cadherin 7, type 2 -2.11528
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) -2.0972
DGKZ diacylglycerol kinase, zeta -2.0911
NOL4 nucleolar protein 4 -2.0911
NBPF14 neuroblastoma breakpoint family, member 14 -2.08986
LCLAT1 lysocardiolipin acyltransferase 1 -2.0845
CCNQ cyclin Q -2.08118
AKAP12 A kinase (PRKA) anchor protein 12 -2.08118
H2BC9 H2B clustered histone 9 -2.07503
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.07384
TGFBI transforming growth factor, beta-induced, 68kDa -2.06751
AKAP6 A kinase (PRKA) anchor protein 6 -2.05155
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B -2.0495
NSUN5 NOP2/Sun domain family, member 5 -2.04565
OPLAH 5-oxoprolinase (ATP-hydrolysing) -2.02812
TBC1D5 TBC1 domain family, member 5 -2.00612