| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.324111 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.234441 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.202767 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.172024 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.155384 |
| CANX | calnexin | 0.125959 |
| CALR | calreticulin | 0.12377 |
| SQSTM1 | sequestosome 1 | 0.109173 |
| AHNAK | AHNAK nucleoprotein | 0.104639 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0922866 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.08634 |
| HDAC9 | histone deacetylase 9 | 0.0831134 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0813561 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0805104 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0774717 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0757168 |
| PTMA | prothymosin, alpha | 0.0735762 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0732951 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0711505 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0707483 |
| MAP1B | microtubule-associated protein 1B | 0.0664479 |
| NAV2 | neuron navigator 2 | 0.0650495 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0644103 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0637745 |
| LDHA | lactate dehydrogenase A | 0.0613931 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0601597 |
| FSTL1 | follistatin-like 1 | 0.0596429 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0589676 |
| CSTB | cystatin B (stefin B) | 0.0566685 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.056259 |
| DST | dystonin | 0.0554628 |
| GOLGA4 | golgin A4 | 0.0548296 |
| ENO1 | enolase 1, (alpha) | 0.0545455 |
| TPM3 | tropomyosin 3 | 0.0540971 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0527854 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0521888 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0513934 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0508978 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0495831 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0494267 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0492181 |
| RND3 | Rho family GTPase 3 | 0.0478754 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0477566 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0465264 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0454243 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0451242 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.044825 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0434322 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0433569 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0424464 |
| CD109 | CD109 molecule | 0.0423693 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0419962 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0402073 |
| SEPTIN9 | septin 9 | 0.0396051 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0390886 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0389521 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0386594 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0386254 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.038205 |
| SET | SET nuclear proto-oncogene | 0.0378378 |
| MSI2 | musashi RNA-binding protein 2 | 0.0377003 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0358288 |
| RPL23 | ribosomal protein L23 | 0.0355419 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0353703 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0346826 |
| RPL12 | ribosomal protein L12 | 0.034445 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0344355 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0344176 |
| DSPP | dentin sialophosphoprotein | 0.0341351 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0338542 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0337699 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0337256 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0333156 |
| ANXA2 | annexin A2 | 0.033162 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0331614 |
| TPM4 | tropomyosin 4 | 0.0327599 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0326846 |
| RPS8 | ribosomal protein S8 | 0.0322728 |
| CENPF | centromere protein F, 350/400kDa | 0.0322681 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0321511 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0320209 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0319666 |
| INSIG1 | insulin induced gene 1 | 0.0319012 |
| ASPH | aspartate beta-hydroxylase | 0.0315384 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0314633 |
| JUN | jun proto-oncogene | 0.0310526 |
| FLNA | filamin A, alpha | 0.0308931 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0307421 |
| ANXA1 | annexin A1 | 0.0306724 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0303678 |
| OR51B5 | olfactory receptor, family 51, subfamily B, member 5 | 0.0302598 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0301492 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0299836 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0296972 |
| RPS6 | ribosomal protein S6 | 0.0289947 |
| FLNB | filamin B, beta | 0.0284114 |
| ADM | adrenomedullin | 0.0283139 |
| MSN | moesin | 0.0280653 |
| CD44 | CD44 molecule (Indian blood group) | 0.0279383 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0276327 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.193255 |
| LOX | lysyl oxidase | -0.096067 |
| MT2A | metallothionein 2A | -0.0903972 |
| PLAT | plasminogen activator, tissue | -0.0784791 |
| TMSB10 | thymosin beta 10 | -0.0719515 |
| VIM | vimentin | -0.0709313 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0609914 |
| FN1 | fibronectin 1 | -0.0583016 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0554957 |
| SUCNR1 | succinate receptor 1 | -0.0537151 |
| MT1X | metallothionein 1X | -0.0532256 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.052841 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0505315 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0482666 |
| NAV1 | neuron navigator 1 | -0.0447553 |
| COL1A2 | collagen, type I, alpha 2 | -0.0442616 |
| LOXL2 | lysyl oxidase-like 2 | -0.0424411 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.041771 |
| HLA-B | major histocompatibility complex, class I, B | -0.0409186 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0373821 |
| PRSS23 | protease, serine, 23 | -0.0363949 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0358644 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.035137 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0342453 |
| MX2 | MX dynamin-like GTPase 2 | -0.0332173 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0323745 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.030897 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0286108 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0278631 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.027408 |
| FBN1 | fibrillin 1 | -0.027261 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0270508 |
| S100A4 | S100 calcium binding protein A4 | -0.0266728 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0255143 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0246838 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0245965 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0235093 |
| COL5A1 | collagen, type V, alpha 1 | -0.0232582 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0231456 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0212799 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0204212 |
| TPM1 | tropomyosin 1 (alpha) | -0.0202222 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0200364 |
| GLIS3 | GLIS family zinc finger 3 | -0.0197378 |
| DCLK2 | doublecortin-like kinase 2 | -0.0189147 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0185052 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0184559 |
| TENM3 | teneurin transmembrane protein 3 | -0.0179173 |
| MYADM | myeloid-associated differentiation marker | -0.0178923 |
| TAPBP | TAP binding protein (tapasin) | -0.0176596 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0176299 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0175473 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0175395 |
| PXDN | peroxidasin | -0.0172612 |
| NPR2 | natriuretic peptide receptor 2 | -0.0171367 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0171 |
| MRC2 | mannose receptor, C type 2 | -0.0169849 |
| HLA-C | major histocompatibility complex, class I, C | -0.0163217 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.015885 |
| BSG | basigin (Ok blood group) | -0.0158665 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0154349 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0151815 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0151751 |
| DGKG | diacylglycerol kinase, gamma 90kDa | -0.0151473 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0147798 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0147128 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.014688 |
| GNAS | GNAS complex locus | -0.0144858 |
| PLXNA2 | plexin A2 | -0.0143751 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0143435 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0143078 |
| SP3 | Sp3 transcription factor | -0.0141627 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.014056 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0137272 |
| CD99 | CD99 molecule | -0.0136305 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0134606 |
| JAZF1 | JAZF zinc finger 1 | -0.0134379 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0134137 |
| HOXB3 | homeobox B3 | -0.0134014 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0133966 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.013316 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0131302 |
| RIGI | RNA sensor RIG-I | -0.0131086 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0129118 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0127037 |
| KLHL24 | kelch-like family member 24 | -0.0126882 |
| LAMA5 | laminin, alpha 5 | -0.01248 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0124031 |
| SMIM44 | small integral membrane protein 44 | -0.0122421 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0122115 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0121132 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0120636 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0119718 |
| RBM25 | RNA binding motif protein 25 | -0.0119617 |
| JAK2 | Janus kinase 2 | -0.0119211 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0118901 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0116802 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0116528 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0116485 |
| TNS3 | tensin 3 | -0.011545 |
