| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.231245 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.144043 |
| EXT1 | exostosin glycosyltransferase 1 | 0.131455 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.13142 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.125283 |
| INTS6 | integrator complex subunit 6 | 0.124074 |
| FNDC3B | fibronectin type III domain containing 3B | 0.123318 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.119808 |
| SMAD3 | SMAD family member 3 | 0.106301 |
| ASPH | aspartate beta-hydroxylase | 0.103507 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.102011 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.100084 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0978441 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0944849 |
| CANX | calnexin | 0.0903572 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0872424 |
| ZNF292 | zinc finger protein 292 | 0.0808948 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0785991 |
| B2M | beta-2-microglobulin | 0.0758016 |
| HKDC1 | hexokinase domain containing 1 | 0.0745915 |
| ANXA2 | annexin A2 | 0.0745741 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0735309 |
| GOLGB1 | golgin B1 | 0.0733492 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.071899 |
| ENO1 | enolase 1, (alpha) | 0.070577 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0674745 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0667927 |
| DST | dystonin | 0.0659339 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0656918 |
| RNF213 | ring finger protein 213 | 0.0629257 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0624133 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0613303 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0612595 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0609609 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0595477 |
| PDZD8 | PDZ domain containing 8 | 0.0590967 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0586579 |
| FTL | ferritin, light polypeptide | 0.0579819 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0578244 |
| GOLGA4 | golgin A4 | 0.0572765 |
| FNIP1 | folliculin interacting protein 1 | 0.0572051 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0564181 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0560708 |
| RPL23 | ribosomal protein L23 | 0.0534506 |
| EFNB2 | ephrin-B2 | 0.0522121 |
| TOP1 | topoisomerase (DNA) I | 0.0518136 |
| SEPTIN9 | septin 9 | 0.0499471 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0484272 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0481967 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0470382 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0469702 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0467694 |
| SIK3 | SIK family kinase 3 | 0.0465449 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0464546 |
| DIAPH1 | diaphanous-related formin 1 | 0.0461805 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0446374 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0446368 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0444098 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0443229 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0434931 |
| MYO10 | myosin X | 0.0434918 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.04272 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0424874 |
| JMJD1C | jumonji domain containing 1C | 0.042227 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.04194 |
| SPAG9 | sperm associated antigen 9 | 0.0413294 |
| LDHA | lactate dehydrogenase A | 0.0402208 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0401297 |
| KYNU | kynureninase | 0.040042 |
| PMM2 | phosphomannomutase 2 | 0.0399842 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0398409 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0395302 |
| HM13 | histocompatibility (minor) 13 | 0.0393235 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0389235 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.038837 |
| FNIP2 | folliculin interacting protein 2 | 0.0386267 |
| SFTPA2 | surfactant protein A2 | 0.0386159 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0382427 |
| MSI2 | musashi RNA-binding protein 2 | 0.0381588 |
| TRIM2 | tripartite motif containing 2 | 0.0379925 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0376697 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0373301 |
| MYO5B | myosin VB | 0.0371642 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0369668 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0364171 |
| SQSTM1 | sequestosome 1 | 0.0359631 |
| RPS8 | ribosomal protein S8 | 0.0351341 |
| AREG | amphiregulin | 0.0350519 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0350108 |
| FAT1 | FAT atypical cadherin 1 | 0.0350026 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0349962 |
| DSPP | dentin sialophosphoprotein | 0.0345583 |
| TMC5 | transmembrane channel-like 5 | 0.0344067 |
| MCU | mitochondrial calcium uniporter | 0.0341045 |
| RAB10 | RAB10, member RAS oncogene family | 0.0333513 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0333052 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0330026 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.032794 |
| CLTC | clathrin, heavy chain (Hc) | 0.0327874 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0325911 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.121629 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0775682 |
| VCL | vinculin | -0.07089 |
| EGR1 | early growth response 1 | -0.0588093 |
| NDRG1 | N-myc downstream regulated 1 | -0.0529793 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0527606 |
| RNF43 | ring finger protein 43 | -0.0498025 |
| TXNIP | thioredoxin interacting protein | -0.0450354 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0441879 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0408867 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0406201 |
| TMEM62 | transmembrane protein 62 | -0.0402615 |
| NCKAP5 | NCK-associated protein 5 | -0.039451 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0392608 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0376003 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0372275 |
| H1-0 | H1.0 linker histone | -0.0371517 |
| NPSR1 | neuropeptide S receptor 1 | -0.0354882 |
| HLA-B | major histocompatibility complex, class I, B | -0.0350164 |
| MECOM | MDS1 and EVI1 complex locus | -0.0342007 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0337407 |
| TC2N | tandem C2 domains, nuclear | -0.033739 |
| DIAPH3 | diaphanous-related formin 3 | -0.0324065 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0306254 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0305182 |
| LYZ | lysozyme | -0.0297883 |
| ATP10B | ATPase, class V, type 10B | -0.0292044 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0290437 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0286643 |
| ACTN4 | actinin, alpha 4 | -0.0281578 |
| PLSCR1 | phospholipid scramblase 1 | -0.0281386 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0279427 |
| TUFT1 | tuftelin 1 | -0.0274993 |
| TNS4 | tensin 4 | -0.0272378 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0269919 |
| FOXP1 | forkhead box P1 | -0.0269167 |
| PHF3 | PHD finger protein 3 | -0.0268595 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0265482 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0262265 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.025964 |
| JUP | junction plakoglobin | -0.0258513 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0257661 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0254503 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.025253 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.0248453 |
| KLHL24 | kelch-like family member 24 | -0.0247188 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0246831 |
| BRCA2 | breast cancer 2, early onset | -0.024579 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0244534 |
| MYO1E | myosin IE | -0.0241448 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0241002 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0240587 |
| MEIS2 | Meis homeobox 2 | -0.0240436 |
| MUC20 | mucin 20, cell surface associated | -0.0238531 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0237573 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0233146 |
| RIGI | RNA sensor RIG-I | -0.0232052 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0230648 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0223967 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0221964 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.021968 |
| IL20RA | interleukin 20 receptor, alpha | -0.0218741 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0218634 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0216531 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.0216239 |
| OGA | O-GlcNAcase | -0.0211341 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0211286 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0209259 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0208408 |
| MX2 | MX dynamin-like GTPase 2 | -0.0207548 |
| FOXO3 | forkhead box O3 | -0.0207242 |
| MT1X | metallothionein 1X | -0.0205303 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0204764 |
| FMN1 | formin 1 | -0.0204483 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0204441 |
| CCNL1 | cyclin L1 | -0.0198945 |
| EZR | ezrin | -0.0198164 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.0197775 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.0194519 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0193964 |
| IFT88 | intraflagellar transport 88 | -0.0193895 |
| MKI67 | marker of proliferation Ki-67 | -0.0189892 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | -0.0187334 |
| SMIM14 | small integral membrane protein 14 | -0.0187271 |
| HMGB1 | high mobility group box 1 | -0.0186857 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | -0.0186553 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0186278 |
| HDAC8 | histone deacetylase 8 | -0.018477 |
| PTEN | phosphatase and tensin homolog | -0.0183979 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0182554 |
| GRAMD2B | GRAM domain containing 2B | -0.0176989 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.0176842 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0176798 |
| LASP1 | LIM and SH3 protein 1 | -0.0175319 |
| TPM4 | tropomyosin 4 | -0.0174192 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0173495 |
| ALPK1 | alpha-kinase 1 | -0.0172066 |
| RAD51B | RAD51 paralog B | -0.0170683 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0170624 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0170594 |
