| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.319876 |
| COL6A3 | collagen, type VI, alpha 3 | 0.239771 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.187497 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.174284 |
| FN1 | fibronectin 1 | 0.160483 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.146377 |
| FNDC3B | fibronectin type III domain containing 3B | 0.136037 |
| CALR | calreticulin | 0.119201 |
| ENO1 | enolase 1, (alpha) | 0.115213 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.110513 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.106633 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0997586 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0975034 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0953923 |
| CADM1 | cell adhesion molecule 1 | 0.0895723 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0858321 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0796666 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.073667 |
| CD44 | CD44 molecule (Indian blood group) | 0.0719794 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0718423 |
| CANX | calnexin | 0.071202 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0706028 |
| LDHA | lactate dehydrogenase A | 0.0699749 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0685386 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0670411 |
| VEGFA | vascular endothelial growth factor A | 0.0659972 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0638869 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0631912 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.060367 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0588762 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.056388 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.055133 |
| ADM | adrenomedullin | 0.0537705 |
| CDH13 | cadherin 13 | 0.0532323 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0512022 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0491395 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0489048 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0474448 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0474122 |
| COL1A2 | collagen, type I, alpha 2 | 0.0465479 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0460118 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.044845 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0447436 |
| TFG | TRK-fused gene | 0.0445464 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | 0.0442894 |
| GOLGB1 | golgin B1 | 0.0433566 |
| RPS8 | ribosomal protein S8 | 0.043272 |
| RPL23 | ribosomal protein L23 | 0.0424505 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0417164 |
| ARRDC3 | arrestin domain containing 3 | 0.0416932 |
| SP100 | SP100 nuclear antigen | 0.0408166 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.04069 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0405996 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0398665 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0392509 |
| TRAM1 | translocation associated membrane protein 1 | 0.0390382 |
| AHNAK | AHNAK nucleoprotein | 0.0385275 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0376745 |
| INHBA | inhibin, beta A | 0.037575 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0375063 |
| JUN | jun proto-oncogene | 0.0373454 |
| MYO10 | myosin X | 0.0370403 |
| GOLGA4 | golgin A4 | 0.0362594 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0358578 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0357875 |
| IRF1 | interferon regulatory factor 1 | 0.03499 |
| FBN1 | fibrillin 1 | 0.0348004 |
| ANXA2 | annexin A2 | 0.034544 |
| GANAB | glucosidase, alpha; neutral AB | 0.0344582 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0339117 |
| SPAG9 | sperm associated antigen 9 | 0.0338527 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.033461 |
| RPL7 | ribosomal protein L7 | 0.0332206 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0324889 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0324387 |
| RPS6 | ribosomal protein S6 | 0.0324152 |
| HDAC9 | histone deacetylase 9 | 0.0322311 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0320923 |
| FMNL2 | formin-like 2 | 0.0318685 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.031767 |
| POSTN | periostin, osteoblast specific factor | 0.0317205 |
| B2M | beta-2-microglobulin | 0.0314387 |
| NAV2 | neuron navigator 2 | 0.0312175 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0310413 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0309557 |
| RLF | rearranged L-myc fusion | 0.0308247 |
| APP | amyloid beta (A4) precursor protein | 0.0307785 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0306764 |
| PGM3 | phosphoglucomutase 3 | 0.03049 |
| CLTC | clathrin, heavy chain (Hc) | 0.030455 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0304425 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0304329 |
| PTK2 | protein tyrosine kinase 2 | 0.03022 |
| S100A9 | S100 calcium binding protein A9 | 0.0301599 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0301574 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0298183 |
| MLF1 | myeloid leukemia factor 1 | 0.0297658 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0296372 |
| HYOU1 | hypoxia up-regulated 1 | 0.0294835 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0293963 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.189104 |
| COL1A1 | collagen, type I, alpha 1 | -0.107452 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0986092 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0807236 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0803827 |
| HMGA2 | high mobility group AT-hook 2 | -0.0554193 |
| NDRG1 | N-myc downstream regulated 1 | -0.0489598 |
| TPM4 | tropomyosin 4 | -0.041039 |
| GLIS3 | GLIS family zinc finger 3 | -0.0387868 |
| MT1X | metallothionein 1X | -0.0378345 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0352625 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0319271 |
| CAVIN1 | caveolae associated protein 1 | -0.0319146 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0312785 |
| LOX | lysyl oxidase | -0.0273048 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0272901 |
| COL5A1 | collagen, type V, alpha 1 | -0.0266591 |
| STC1 | stanniocalcin 1 | -0.026582 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026076 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0254722 |
| MMP3 | matrix metallopeptidase 3 | -0.0253111 |
| ACTG1 | actin gamma 1 | -0.0248523 |
| LOXL2 | lysyl oxidase-like 2 | -0.0242755 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0232375 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0231734 |
| TMSB10 | thymosin beta 10 | -0.0225772 |
| SMYD3 | SET and MYND domain containing 3 | -0.0219996 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0216279 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0208665 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.020378 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.020315 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0196194 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0195124 |
| EGR1 | early growth response 1 | -0.0194622 |
| CCDC91 | coiled-coil domain containing 91 | -0.0194028 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0191573 |
| NRP1 | neuropilin 1 | -0.0191287 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0190982 |
| SYNJ2 | synaptojanin 2 | -0.0187495 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0186394 |
| SBF2 | SET binding factor 2 | -0.018341 |
| PXDN | peroxidasin | -0.018221 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0178682 |
| GNAS | GNAS complex locus | -0.0177847 |
| HLA-B | major histocompatibility complex, class I, B | -0.017588 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0175869 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0173329 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0171732 |
| RUNX1 | runt-related transcription factor 1 | -0.0171256 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0154843 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0152952 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0152811 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0152117 |
| EHD2 | EH-domain containing 2 | -0.0151692 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0149839 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.014971 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0149519 |
| BNC2 | basonuclin 2 | -0.0149283 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0147999 |
| FBXO32 | F-box protein 32 | -0.0144121 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0143872 |
| NAV1 | neuron navigator 1 | -0.0143187 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0142989 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0142516 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0140035 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0137421 |
| FTL | ferritin, light polypeptide | -0.0134056 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0133258 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0132203 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0130496 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0130424 |
| VCL | vinculin | -0.0130114 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0129685 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0129008 |
| ANAPC5 | anaphase promoting complex subunit 5 | -0.0127505 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0126607 |
| SH3PXD2B | SH3 and PX domains 2B | -0.0123641 |
| TPM1 | tropomyosin 1 (alpha) | -0.012345 |
| HAS2 | hyaluronan synthase 2 | -0.012253 |
| TAPBP | TAP binding protein (tapasin) | -0.0122214 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0122186 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0121598 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.012154 |
| TMSB4X | thymosin beta 4, X-linked | -0.0120802 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0119271 |
| PRR16 | proline rich 16 | -0.0118969 |
| PRRX1 | paired related homeobox 1 | -0.0118347 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0116985 |
| XPO7 | exportin 7 | -0.0115879 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0115809 |
| AOPEP | aminopeptidase O (putative) | -0.0115566 |
| PRELID2 | PRELI domain containing 2 | -0.0115003 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0114892 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0114159 |
| LIMA1 | LIM domain and actin binding 1 | -0.0113236 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) | -0.011288 |
| EHBP1 | EH domain binding protein 1 | -0.0112021 |
| EBF1 | early B-cell factor 1 | -0.0111517 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0111288 |
| LASP1 | LIM and SH3 protein 1 | -0.0110881 |
