| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MTSS1 | metastasis suppressor 1 | 0.143961 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.113888 |
| SLC35F3 | solute carrier family 35, member F3 | 0.110834 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100394 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0998064 |
| RAI14 | retinoic acid induced 14 | 0.0994154 |
| AHNAK | AHNAK nucleoprotein | 0.0904007 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0889504 |
| ASPH | aspartate beta-hydroxylase | 0.0843138 |
| CD44 | CD44 molecule (Indian blood group) | 0.081171 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0787335 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0768142 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0764535 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0735632 |
| PLEC | plectin | 0.0735255 |
| ENO1 | enolase 1, (alpha) | 0.0733325 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0710997 |
| CANX | calnexin | 0.0661601 |
| LAMC2 | laminin, gamma 2 | 0.0657483 |
| EXT1 | exostosin glycosyltransferase 1 | 0.065612 |
| TPM3 | tropomyosin 3 | 0.0611328 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0568833 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0568638 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0567362 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0562633 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0515818 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0509502 |
| SIK3 | SIK family kinase 3 | 0.0504647 |
| PTK2 | protein tyrosine kinase 2 | 0.0503277 |
| RASAL2 | RAS protein activator like 2 | 0.0481942 |
| NAV2 | neuron navigator 2 | 0.0472476 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | 0.0467977 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0453925 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0447916 |
| DOCK5 | dedicator of cytokinesis 5 | 0.044558 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0444209 |
| KIAA1217 | KIAA1217 | 0.0442641 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0436189 |
| OSMR | oncostatin M receptor | 0.0435731 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0435035 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419209 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0415863 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0414796 |
| ANXA2 | annexin A2 | 0.0414145 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0410799 |
| SMAD3 | SMAD family member 3 | 0.040664 |
| ARRDC3 | arrestin domain containing 3 | 0.04049 |
| SEPTIN9 | septin 9 | 0.0399857 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0399405 |
| FNIP1 | folliculin interacting protein 1 | 0.0393331 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0392101 |
| RPL12 | ribosomal protein L12 | 0.0389606 |
| MYOF | myoferlin | 0.0387342 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0383962 |
| PRELID2 | PRELI domain containing 2 | 0.0380858 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0380547 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0379972 |
| AMOTL1 | angiomotin like 1 | 0.037917 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0376309 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0368392 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.036044 |
| FLNB | filamin B, beta | 0.0357216 |
| DST | dystonin | 0.0353861 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0352846 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0351605 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0346007 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0345124 |
| GOLGB1 | golgin B1 | 0.034248 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0341633 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0340501 |
| RRBP1 | ribosome binding protein 1 | 0.0338493 |
| CDCP1 | CUB domain containing protein 1 | 0.0328317 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0327745 |
| TXNIP | thioredoxin interacting protein | 0.0327334 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0327119 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0324254 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0321421 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0320724 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0318084 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0313798 |
| RAB10 | RAB10, member RAS oncogene family | 0.0312951 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0311 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0305883 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.030454 |
| LDHA | lactate dehydrogenase A | 0.0302822 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0302361 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0301758 |
| CDK6 | cyclin-dependent kinase 6 | 0.0299811 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0299153 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0299062 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0294298 |
| FAM107B | family with sequence similarity 107, member B | 0.0292016 |
| TOP1 | topoisomerase (DNA) I | 0.0291013 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0290615 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.028798 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0282904 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0280502 |
| BARX2 | BARX homeobox 2 | 0.0277012 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0276171 |
| STK4 | serine/threonine kinase 4 | 0.0275002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.176899 |
| NDRG1 | N-myc downstream regulated 1 | -0.11318 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0927164 |
| IGF2 | insulin-like growth factor 2 | -0.0840099 |
| TMSB10 | thymosin beta 10 | -0.074977 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0712913 |
| PTMA | prothymosin, alpha | -0.0689971 |
| POTEF | POTE ankyrin domain family, member F | -0.0624034 |
| SULF1 | sulfatase 1 | -0.0608534 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0565157 |
| FOXO1 | forkhead box O1 | -0.0554724 |
| GNAS | GNAS complex locus | -0.0522088 |
| MEF2A | myocyte enhancer factor 2A | -0.0504455 |
| RBM39 | RNA binding motif protein 39 | -0.0503875 |
| STC1 | stanniocalcin 1 | -0.0488615 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0475074 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0471084 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0464814 |
| FTL | ferritin, light polypeptide | -0.0455898 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0454793 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.044786 |
| WASF2 | WAS protein family, member 2 | -0.0436744 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0419852 |
| OGA | O-GlcNAcase | -0.0417903 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0407341 |
| EGR1 | early growth response 1 | -0.0377377 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0372189 |
| S100A10 | S100 calcium binding protein A10 | -0.0369361 |
| MT1X | metallothionein 1X | -0.0356784 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0323693 |
| LMNA | lamin A/C | -0.0322457 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0303389 |
| YBX3 | Y box binding protein 3 | -0.0302562 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0301603 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0301562 |
| SERINC3 | serine incorporator 3 | -0.0299499 |
| H1-0 | H1.0 linker histone | -0.0298581 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0292614 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0290803 |
| PLTP | phospholipid transfer protein | -0.028926 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0285122 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0279275 |
| KLHL24 | kelch-like family member 24 | -0.0275514 |
| RPS25 | ribosomal protein S25 | -0.0275024 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0267864 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0262048 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0262012 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0260115 |
| BCL2L1 | BCL2-like 1 | -0.0259803 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0258442 |
| KRT17 | keratin 17, type I | -0.0258326 |
| ITGB4 | integrin, beta 4 | -0.0257579 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0256587 |
| PLAC8 | placenta-specific 8 | -0.0255771 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.025554 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0253663 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0247357 |
| CTSD | cathepsin D | -0.0245235 |
| TMSB4X | thymosin beta 4, X-linked | -0.0242532 |
| RPL35A | ribosomal protein L35a | -0.0239815 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0238578 |
| HLA-E | major histocompatibility complex, class I, E | -0.023836 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0237438 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0233837 |
| BSG | basigin (Ok blood group) | -0.0228567 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0228091 |
| RPS21 | ribosomal protein S21 | -0.0227061 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0226261 |
| HLA-B | major histocompatibility complex, class I, B | -0.0224761 |
| RPLP1 | ribosomal protein, large, P1 | -0.0223779 |
| PFN1 | profilin 1 | -0.0223671 |
| HBP1 | HMG-box transcription factor 1 | -0.021382 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0210864 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0210781 |
| LAMA5 | laminin, alpha 5 | -0.021044 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | -0.0210381 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0208478 |
| GOLPH3L | golgi phosphoprotein 3-like | -0.0208229 |
| FOXO3 | forkhead box O3 | -0.0208228 |
| S100A11 | S100 calcium binding protein A11 | -0.0204261 |
| PALLD | palladin, cytoskeletal associated protein | -0.0203901 |
| MEF2D | myocyte enhancer factor 2D | -0.0202619 |
| CD99 | CD99 molecule | -0.0201459 |
| NECTIN1 | nectin cell adhesion molecule 1 | -0.0201129 |
| SMIM14 | small integral membrane protein 14 | -0.0198206 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0197692 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0196291 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0195065 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0192509 |
| ARF4 | ADP-ribosylation factor 4 | -0.0191755 |
| CST3 | cystatin C | -0.0191159 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0190872 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0190869 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | -0.0190857 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0190344 |
| S100A6 | S100 calcium binding protein A6 | -0.0188574 |
| RNF38 | ring finger protein 38 | -0.0187748 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0187646 |
| PTEN | phosphatase and tensin homolog | -0.0186712 |
| S100A4 | S100 calcium binding protein A4 | -0.0186534 |
