| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.230787 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.147579 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.143439 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.138592 |
| LDHA | lactate dehydrogenase A | 0.119111 |
| ASPH | aspartate beta-hydroxylase | 0.103002 |
| ENO1 | enolase 1, (alpha) | 0.095426 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0934177 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0812956 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0802852 |
| DSPP | dentin sialophosphoprotein | 0.0773762 |
| MED13 | mediator complex subunit 13 | 0.0760635 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0746842 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0724459 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0720094 |
| AHNAK | AHNAK nucleoprotein | 0.0711903 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0705064 |
| KRT18 | keratin 18, type I | 0.06782 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0655219 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0629831 |
| ITGA6 | integrin, alpha 6 | 0.0618706 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0608176 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0606224 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0567572 |
| CANX | calnexin | 0.0561545 |
| CALR | calreticulin | 0.0551042 |
| LMO7 | LIM domain 7 | 0.054592 |
| HDLBP | high density lipoprotein binding protein | 0.052821 |
| PDZD8 | PDZ domain containing 8 | 0.0526329 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0517921 |
| B2M | beta-2-microglobulin | 0.0514647 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0513987 |
| SQSTM1 | sequestosome 1 | 0.0492518 |
| TXNIP | thioredoxin interacting protein | 0.0478529 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0467694 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0460049 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0447946 |
| MYO5B | myosin VB | 0.0445068 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0443684 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0432802 |
| FAT1 | FAT atypical cadherin 1 | 0.0428865 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0410653 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0409908 |
| SIK3 | SIK family kinase 3 | 0.040555 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0405059 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0395536 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0394268 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0384891 |
| CRY1 | cryptochrome circadian clock 1 | 0.0374535 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0364299 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0360243 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0359399 |
| GOLGA4 | golgin A4 | 0.0358814 |
| FTL | ferritin, light polypeptide | 0.034497 |
| CD44 | CD44 molecule (Indian blood group) | 0.0344056 |
| PGK1 | phosphoglycerate kinase 1 | 0.0342271 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0339399 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0336496 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0334929 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.033042 |
| WHRN | whirlin | 0.0327896 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0326489 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0326197 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0325824 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0325329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0320816 |
| MT2A | metallothionein 2A | 0.0320717 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0320041 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0319845 |
| GOLGB1 | golgin B1 | 0.0318097 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0317906 |
| RPS8 | ribosomal protein S8 | 0.0317517 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.031629 |
| PCBP2 | poly(rC) binding protein 2 | 0.0315717 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.031418 |
| CLTC | clathrin, heavy chain (Hc) | 0.0312837 |
| ANXA2 | annexin A2 | 0.0309879 |
| BRD2 | bromodomain containing 2 | 0.0309774 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.03051 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0304206 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0302085 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0301182 |
| PLEC | plectin | 0.0292434 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.028817 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0280975 |
| LAMC2 | laminin, gamma 2 | 0.0279041 |
| KIAA1671 | KIAA1671 | 0.0278545 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0276209 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0274904 |
| RPL23 | ribosomal protein L23 | 0.027214 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0271371 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0270627 |
| RPL3 | ribosomal protein L3 | 0.0269619 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0269353 |
| RPL7 | ribosomal protein L7 | 0.0263707 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0262272 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0261828 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0254032 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0252108 |
| SGMS2 | sphingomyelin synthase 2 | 0.0248438 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.231402 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.121212 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.11536 |
| VCL | vinculin | -0.111949 |
| TNS4 | tensin 4 | -0.105397 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.10531 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.103942 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0892122 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0781094 |
| GPHN | gephyrin | -0.0709431 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0629737 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0628425 |
| TMSB10 | thymosin beta 10 | -0.0627961 |
| RNF43 | ring finger protein 43 | -0.0600322 |
| PTMA | prothymosin, alpha | -0.0584296 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0573987 |
| FLNB | filamin B, beta | -0.0550735 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.051514 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0485094 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0467439 |
| MED13L | mediator complex subunit 13-like | -0.0444439 |
| CALB1 | calbindin 1, 28kDa | -0.0434923 |
| ITGB4 | integrin, beta 4 | -0.0414856 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0403321 |
| NDRG1 | N-myc downstream regulated 1 | -0.040324 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0393936 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0391964 |
| RAD51B | RAD51 paralog B | -0.0390962 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0377892 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.03739 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0367406 |
| FHL2 | four and a half LIM domains 2 | -0.0365019 |
| PRSS3 | protease, serine, 3 | -0.0346213 |
| NRXN3 | neurexin 3 | -0.0343806 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0341339 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.033994 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0338807 |
| NFIA | nuclear factor I/A | -0.0336052 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0332341 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0321755 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0316013 |
| ABHD2 | abhydrolase domain containing 2 | -0.031548 |
| FERMT1 | fermitin family member 1 | -0.0314198 |
| RNF217 | ring finger protein 217 | -0.0311376 |
| MYO1D | myosin ID | -0.0309844 |
| PALLD | palladin, cytoskeletal associated protein | -0.0308609 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0306639 |
| DENND1A | DENN/MADD domain containing 1A | -0.0305284 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0304864 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0303571 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0302039 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0301139 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0297138 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0294886 |
| RIN2 | Ras and Rab interactor 2 | -0.0293772 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0287908 |
| KLK10 | kallikrein-related peptidase 10 | -0.028344 |
| EGR1 | early growth response 1 | -0.028318 |
| SETD5 | SET domain containing 5 | -0.0281468 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0274257 |
| ANXA3 | annexin A3 | -0.0273063 |
| MECOM | MDS1 and EVI1 complex locus | -0.027288 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0270766 |
| RBM39 | RNA binding motif protein 39 | -0.0270252 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.026835 |
| EHBP1 | EH domain binding protein 1 | -0.0264906 |
| HDAC2 | histone deacetylase 2 | -0.0260108 |
| S100P | S100 calcium binding protein P | -0.0258835 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0258496 |
| POTEF | POTE ankyrin domain family, member F | -0.0258112 |
| BCL2L1 | BCL2-like 1 | -0.0256987 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0256295 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.025545 |
| PTEN | phosphatase and tensin homolog | -0.0254673 |
| FOXP2 | forkhead box P2 | -0.0254012 |
| OGA | O-GlcNAcase | -0.0253043 |
| FOSL1 | FOS-like antigen 1 | -0.0253012 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0252583 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0251048 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0250213 |
| ACTN4 | actinin, alpha 4 | -0.0246444 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.024505 |
| GDF15 | growth differentiation factor 15 | -0.0243234 |
| FOXO1 | forkhead box O1 | -0.024266 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0241002 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0239719 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0238317 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0237918 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0237571 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.0234858 |
| CADPS | Ca++-dependent secretion activator | -0.0229859 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0229109 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0228832 |
| ETNK1 | ethanolamine kinase 1 | -0.0228716 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0228206 |
| RPL35A | ribosomal protein L35a | -0.0226674 |
| NEK7 | NIMA-related kinase 7 | -0.0226051 |
| MSI2 | musashi RNA-binding protein 2 | -0.022571 |
| RPS24 | ribosomal protein S24 | -0.022398 |
| FOXP1 | forkhead box P1 | -0.0221983 |
