| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.223556 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.155347 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.131428 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.112334 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.10472 |
| PCBP2 | poly(rC) binding protein 2 | 0.0956934 |
| ENO1 | enolase 1, (alpha) | 0.0898902 |
| NAV2 | neuron navigator 2 | 0.0875446 |
| GOLGA4 | golgin A4 | 0.0857113 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0826691 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0822456 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0818214 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0809222 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0768766 |
| CANX | calnexin | 0.0744513 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0731214 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0702954 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0662804 |
| LDHA | lactate dehydrogenase A | 0.0648696 |
| FAM107B | family with sequence similarity 107, member B | 0.062059 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0619207 |
| HDAC9 | histone deacetylase 9 | 0.0614447 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0597782 |
| SMAD3 | SMAD family member 3 | 0.0581976 |
| ANGPTL4 | angiopoietin-like 4 | 0.0569976 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0557248 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0552075 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0542307 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0528568 |
| ANXA2 | annexin A2 | 0.0498931 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0493698 |
| FAM13A | family with sequence similarity 13, member A | 0.0488073 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0459473 |
| CALU | calumenin | 0.0452143 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0442953 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.043235 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.043021 |
| B2M | beta-2-microglobulin | 0.0419372 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0418625 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0417362 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0411247 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0407917 |
| ADM | adrenomedullin | 0.0401208 |
| MAP1B | microtubule-associated protein 1B | 0.0399773 |
| LOXL2 | lysyl oxidase-like 2 | 0.0397146 |
| HDLBP | high density lipoprotein binding protein | 0.0389733 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0386714 |
| JUN | jun proto-oncogene | 0.0385842 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0378194 |
| CA12 | carbonic anhydrase XII | 0.0374886 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0374351 |
| GPATCH2L | G patch domain containing 2-like | 0.0370429 |
| RUNX1 | runt-related transcription factor 1 | 0.0359494 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0352238 |
| FLNB | filamin B, beta | 0.0350873 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0346157 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0345246 |
| RPL23 | ribosomal protein L23 | 0.0344009 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0338473 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0326784 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0324019 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0323557 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0323033 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0317792 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0316218 |
| ANXA1 | annexin A1 | 0.0314938 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0313276 |
| SFTPA2 | surfactant protein A2 | 0.0311654 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0311535 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0311071 |
| CD44 | CD44 molecule (Indian blood group) | 0.0310642 |
| RPS8 | ribosomal protein S8 | 0.0310537 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.031046 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0309493 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0298903 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0296773 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293455 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0293441 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0292581 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0290356 |
| SEPTIN9 | septin 9 | 0.0286788 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0285786 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0285362 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0275022 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0274857 |
| VIM | vimentin | 0.0271727 |
| TNNC1 | troponin C type 1 (slow) | 0.0270434 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0269158 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0268749 |
| ARRDC3 | arrestin domain containing 3 | 0.026808 |
| NGLY1 | N-glycanase 1 | 0.0267813 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0265482 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0264228 |
| RPS12 | ribosomal protein S12 | 0.0263936 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0263519 |
| ASPH | aspartate beta-hydroxylase | 0.0263258 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0260295 |
| SPAG9 | sperm associated antigen 9 | 0.0258657 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0257223 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0253645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.234431 |
| GLCCI1 | glucocorticoid induced 1 | -0.158408 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.124885 |
| CDH13 | cadherin 13 | -0.117359 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.114579 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.109966 |
| TMSB10 | thymosin beta 10 | -0.102321 |
| HMGA2 | high mobility group AT-hook 2 | -0.0996657 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0974605 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0955309 |
| FN1 | fibronectin 1 | -0.0915632 |
| NRG1 | neuregulin 1 | -0.0667411 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0620496 |
| NRP1 | neuropilin 1 | -0.0598162 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0591855 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0575284 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0541229 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0531162 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0515106 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0507354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0498223 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0467123 |
| CLMP | CXADR-like membrane protein | -0.0451772 |
| NTN4 | netrin 4 | -0.0449922 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0448853 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0446693 |
| EFNA5 | ephrin-A5 | -0.0444388 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0432315 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0428837 |
| VRK2 | vaccinia related kinase 2 | -0.042185 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0420909 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0409304 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0399529 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0396518 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0395142 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0393406 |
| PARD3 | par-3 family cell polarity regulator | -0.0391101 |
| MECOM | MDS1 and EVI1 complex locus | -0.0385409 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0381502 |
| ETV6 | ets variant 6 | -0.0380058 |
| NUMB | numb homolog (Drosophila) | -0.0377094 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0376415 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0365887 |
| OSMR | oncostatin M receptor | -0.035587 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0354266 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0341952 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0333354 |
| JMJD1C | jumonji domain containing 1C | -0.0332962 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0327874 |
| CCDC91 | coiled-coil domain containing 91 | -0.0324158 |
| ANXA10 | annexin A10 | -0.0320302 |
| DIAPH2 | diaphanous-related formin 2 | -0.031978 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0318233 |
| MTSS1 | metastasis suppressor 1 | -0.0309553 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0309131 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0307312 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0306668 |
| MEF2A | myocyte enhancer factor 2A | -0.030648 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0305818 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0296955 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0290331 |
| RBM39 | RNA binding motif protein 39 | -0.0290107 |
| POTEF | POTE ankyrin domain family, member F | -0.0288857 |
| STC1 | stanniocalcin 1 | -0.0285159 |
| BMERB1 | bMERB domain containing 1 | -0.0283584 |
| ZNF804A | zinc finger protein 804A | -0.027664 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0267452 |
| DNER | delta/notch-like EGF repeat containing | -0.0266998 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0265712 |
| TJP1 | tight junction protein 1 | -0.0264449 |
| KLHL24 | kelch-like family member 24 | -0.0262741 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0260036 |
| PRR16 | proline rich 16 | -0.0260006 |
| PRRX1 | paired related homeobox 1 | -0.0256641 |
| RUNX2 | runt-related transcription factor 2 | -0.025508 |
| CDK14 | cyclin-dependent kinase 14 | -0.0245521 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0244211 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0241936 |
| FNBP1 | formin binding protein 1 | -0.0240861 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0240665 |
| CUX1 | cut-like homeobox 1 | -0.0240402 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0240396 |
| RAD51B | RAD51 paralog B | -0.0240164 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0239629 |
| TMEM165 | transmembrane protein 165 | -0.0239614 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0239342 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0237584 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0237312 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0236132 |
| NLK | nemo-like kinase | -0.0235698 |
| AOPEP | aminopeptidase O (putative) | -0.023435 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0233894 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0232477 |
| SNX9 | sorting nexin 9 | -0.0232375 |
| SETD5 | SET domain containing 5 | -0.0231609 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0229814 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0229754 |
| HBP1 | HMG-box transcription factor 1 | -0.0227624 |
| R3HDM2 | R3H domain containing 2 | -0.0224598 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0223022 |
