| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.314445 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.302298 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.230614 |
| CANX | calnexin | 0.127589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.126763 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.119855 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.114874 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.106905 |
| AHNAK | AHNAK nucleoprotein | 0.098711 |
| DSPP | dentin sialophosphoprotein | 0.0905462 |
| ENO1 | enolase 1, (alpha) | 0.0884232 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0833287 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0829634 |
| SQSTM1 | sequestosome 1 | 0.0790775 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0788886 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0788629 |
| CALR | calreticulin | 0.0787497 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0716647 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0685278 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0682526 |
| UPP1 | uridine phosphorylase 1 | 0.067682 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0674964 |
| TPM3 | tropomyosin 3 | 0.0646312 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0639421 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0632906 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0626696 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.059837 |
| GOLGA4 | golgin A4 | 0.0593577 |
| ASPH | aspartate beta-hydroxylase | 0.0586457 |
| LDHA | lactate dehydrogenase A | 0.0582178 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0552981 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0549849 |
| GOLGB1 | golgin B1 | 0.0547226 |
| RPS8 | ribosomal protein S8 | 0.053977 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0536948 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0516551 |
| RPL23 | ribosomal protein L23 | 0.051346 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0512558 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0505751 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0499598 |
| TOP1 | topoisomerase (DNA) I | 0.0493712 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0483916 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0482969 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0476411 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0472375 |
| G0S2 | G0/G1 switch 2 | 0.0469701 |
| LAMC2 | laminin, gamma 2 | 0.0467742 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0455831 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0449113 |
| RPS3 | ribosomal protein S3 | 0.0444788 |
| PTMA | prothymosin, alpha | 0.0443354 |
| ANXA2 | annexin A2 | 0.0442567 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0441702 |
| RPL12 | ribosomal protein L12 | 0.0436527 |
| FTL | ferritin, light polypeptide | 0.0435616 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0434117 |
| PTK2 | protein tyrosine kinase 2 | 0.0432433 |
| MAP1B | microtubule-associated protein 1B | 0.0431671 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.043056 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.042566 |
| PLEC | plectin | 0.0424097 |
| RPS6 | ribosomal protein S6 | 0.042111 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0421012 |
| SET | SET nuclear proto-oncogene | 0.042035 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0416262 |
| MX1 | MX dynamin-like GTPase 1 | 0.0412928 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0402934 |
| ARRDC3 | arrestin domain containing 3 | 0.0400166 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0399995 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0392166 |
| VEGFA | vascular endothelial growth factor A | 0.0391154 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0390071 |
| RNF213 | ring finger protein 213 | 0.03881 |
| EFNA5 | ephrin-A5 | 0.0385236 |
| ERBIN | erbb2 interacting protein | 0.0382796 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0382395 |
| RPS17 | ribosomal protein S17 | 0.0379488 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0377427 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0376374 |
| CD109 | CD109 molecule | 0.0373234 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0368751 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0365972 |
| RCOR1 | REST corepressor 1 | 0.0351793 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0351419 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0351393 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0350317 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0349976 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0349695 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.034706 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0339615 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0337531 |
| PCBP2 | poly(rC) binding protein 2 | 0.0336298 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0335651 |
| RPS12 | ribosomal protein S12 | 0.0334776 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0334174 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.033255 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0331881 |
| RAI14 | retinoic acid induced 14 | 0.0329532 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.032622 |
| CLTC | clathrin, heavy chain (Hc) | 0.0324609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105944 |
| ACTG1 | actin gamma 1 | -0.0873844 |
| POTEF | POTE ankyrin domain family, member F | -0.078627 |
| TMSB10 | thymosin beta 10 | -0.0678399 |
| NDRG1 | N-myc downstream regulated 1 | -0.0613071 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0533475 |
| MT2A | metallothionein 2A | -0.0397974 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0362022 |
| FN1 | fibronectin 1 | -0.0330666 |
| HMGA1 | high mobility group AT-hook 1 | -0.0316559 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0277133 |
| RPL35A | ribosomal protein L35a | -0.0268457 |
| FAM3C | family with sequence similarity 3, member C | -0.0259586 |
| FAM162A | family with sequence similarity 162, member A | -0.0258349 |
| CCNL1 | cyclin L1 | -0.0226443 |
| NPC2 | Niemann-Pick disease, type C2 | -0.0214725 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0209999 |
| S100A4 | S100 calcium binding protein A4 | -0.0185477 |
| WTAP | Wilms tumor 1 associated protein | -0.0184006 |
| NEK7 | NIMA-related kinase 7 | -0.0183254 |
| S100A6 | S100 calcium binding protein A6 | -0.0181526 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0179764 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0179657 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0169743 |
| CTSD | cathepsin D | -0.0166647 |
| CLDN4 | claudin 4 | -0.0165964 |
| ABI1 | abl-interactor 1 | -0.0163535 |
| USP3 | ubiquitin specific peptidase 3 | -0.0158263 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0155562 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0155362 |
| KLHL24 | kelch-like family member 24 | -0.0155114 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0145593 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0145257 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0141239 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.0140959 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0140585 |
| MSMO1 | methylsterol monooxygenase 1 | -0.0140028 |
| CDCP1 | CUB domain containing protein 1 | -0.0138754 |
| TXNIP | thioredoxin interacting protein | -0.0138698 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0137686 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0135353 |
| MT1X | metallothionein 1X | -0.0133069 |
| RHEB | Ras homolog enriched in brain | -0.0132182 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.012972 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0129276 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0128865 |
| TMEM263 | transmembrane protein 263 | -0.0127987 |
| MEF2D | myocyte enhancer factor 2D | -0.0125237 |
| S100A10 | S100 calcium binding protein A10 | -0.0124059 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0121994 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0121801 |
| SF1 | splicing factor 1 | -0.0118621 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0117509 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0116969 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0115227 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0114674 |
| TMEM123 | transmembrane protein 123 | -0.0114072 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0112691 |
| AGRN | agrin | -0.011174 |
| FBXO33 | F-box protein 33 | -0.0111362 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.0111015 |
| RPL28 | ribosomal protein L28 | -0.0110066 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -0.0109733 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0109264 |
| TAPBP | TAP binding protein (tapasin) | -0.0108711 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.010783 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0107685 |
| CDK17 | cyclin-dependent kinase 17 | -0.0106419 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0106107 |
| RNF38 | ring finger protein 38 | -0.0106051 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0105316 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0104434 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.010364 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | -0.0103114 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0102921 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0102558 |
| PRPF39 | pre-mRNA processing factor 39 | -0.010116 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0101126 |
| CD46 | CD46 molecule, complement regulatory protein | -0.00997932 |
| FBXO32 | F-box protein 32 | -0.00997641 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00987578 |
| CHMP2B | charged multivesicular body protein 2B | -0.00985198 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | -0.00984005 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.00976175 |
| TFG | TRK-fused gene | -0.00974809 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00966682 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.00961447 |
| MUC20 | mucin 20, cell surface associated | -0.00943227 |
| MUC1 | mucin 1, cell surface associated | -0.00930548 |
| PROSER2 | proline and serine rich 2 | -0.00927242 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00908592 |
| GNAS | GNAS complex locus | -0.00901776 |
| SARAF | store-operated calcium entry-associated regulatory factor | -0.00882856 |
| AREL1 | apoptosis resistant E3 ubiquitin protein ligase 1 | -0.00876008 |
| IER3 | immediate early response 3 | -0.0087587 |
| HBP1 | HMG-box transcription factor 1 | -0.00872212 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.00871927 |
| JUP | junction plakoglobin | -0.00871267 |
| BTG3 | BTG family, member 3 | -0.00869644 |
| SREK1IP1 | SREK1-interacting protein 1 | -0.00857754 |
