| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
157 genes differentially expressed following the EX229_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.287285 |
| FMN1 | formin 1 | 0.213231 |
| RPL23 | ribosomal protein L23 | 0.202539 |
| MT2A | metallothionein 2A | 0.161673 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.152272 |
| ENAH | enabled homolog (Drosophila) | 0.131141 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.123822 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.118326 |
| FNDC3B | fibronectin type III domain containing 3B | 0.112657 |
| RPL19 | ribosomal protein L19 | 0.108061 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.106293 |
| IGF2 | insulin-like growth factor 2 | 0.103386 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0990924 |
| RPL15 | ribosomal protein L15 | 0.098442 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.095656 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0897145 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0879505 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0874771 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0870839 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.084894 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0825789 |
| LAMB1 | laminin, beta 1 | 0.0807304 |
| RPL36A | ribosomal protein L36a | 0.0785986 |
| CALU | calumenin | 0.0776732 |
| CCNI | cyclin I | 0.0709498 |
| MAP1B | microtubule-associated protein 1B | 0.068386 |
| LSAMP | limbic system-associated membrane protein | 0.0674642 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0662999 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0645071 |
| FNIP1 | folliculin interacting protein 1 | 0.0622581 |
| VIM | vimentin | 0.0612382 |
| FTL | ferritin, light polypeptide | 0.0570446 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0570064 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0519678 |
| PTK2 | protein tyrosine kinase 2 | 0.051758 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0513008 |
| CD44 | CD44 molecule (Indian blood group) | 0.0512469 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0497731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0484802 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0458436 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0450438 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0439992 |
| RPS12 | ribosomal protein S12 | 0.0435114 |
| RPLP1 | ribosomal protein, large, P1 | 0.0428841 |
| ZNF148 | zinc finger protein 148 | 0.0426067 |
| RPLP2 | ribosomal protein, large, P2 | 0.0401633 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.040085 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.038883 |
| PTMA | prothymosin, alpha | 0.0368061 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0342851 |
| USP34 | ubiquitin specific peptidase 34 | 0.0335844 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0310628 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0295876 |
| FN1 | fibronectin 1 | 0.0295107 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0282979 |
| DENND1A | DENN/MADD domain containing 1A | 0.0236192 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0229203 |
| TMSB10 | thymosin beta 10 | 0.0224821 |
| CANX | calnexin | 0.0222882 |
| AHNAK | AHNAK nucleoprotein | 0.0208276 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0203843 |
| PUM3 | pumilio RNA binding family member 3 | 0.0166938 |
| RPS6 | ribosomal protein S6 | 0.0148233 |
| ENO1 | enolase 1, (alpha) | 0.0114153 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0105783 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0104226 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.00856332 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.00855216 |
| PARD3 | par-3 family cell polarity regulator | 0.00525287 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.00501861 |
| PRRC2C | proline-rich coiled-coil 2C | 0.00468261 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.00309443 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.00287819 |
| DST | dystonin | 0.00237082 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.00179296 |
| TSC22D2 | TSC22 domain family, member 2 | 0.001008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.282597 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.184219 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.13669 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.133678 |
| LMO7 | LIM domain 7 | -0.13324 |
| ASPH | aspartate beta-hydroxylase | -0.121882 |
| CDH13 | cadherin 13 | -0.11196 |
| NAV2 | neuron navigator 2 | -0.109383 |
| MYO1E | myosin IE | -0.101764 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.100823 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0935979 |
| RORA | RAR-related orphan receptor A | -0.0875642 |
| SMYD3 | SET and MYND domain containing 3 | -0.0808704 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0802475 |
| VCL | vinculin | -0.0800994 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.079435 |
| SETD5 | SET domain containing 5 | -0.0768422 |
| RPL35A | ribosomal protein L35a | -0.076036 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0726947 |
| JMJD1C | jumonji domain containing 1C | -0.07056 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0652983 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0645444 |
| RAD51B | RAD51 paralog B | -0.0640691 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0616137 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0592757 |
| ATXN1 | ataxin 1 | -0.0592001 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0577643 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0576364 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0569881 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0558173 |
| NHSL1 | NHS-like 1 | -0.0557141 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0551589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0542703 |
| PDE10A | phosphodiesterase 10A | -0.0540499 |
| VMP1 | vacuole membrane protein 1 | -0.053966 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0533163 |
| FNDC3A | fibronectin type III domain containing 3A | -0.052966 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0507186 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0497192 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0487099 |
| DTNA | dystrobrevin, alpha | -0.0486014 |
| PRELID2 | PRELI domain containing 2 | -0.0479838 |
| RPS19 | ribosomal protein S19 | -0.0452616 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0417473 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0407691 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0387186 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0374663 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0370584 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0341006 |
| MED13 | mediator complex subunit 13 | -0.0332229 |
| EFNA5 | ephrin-A5 | -0.0327321 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0321863 |
| GOLGA4 | golgin A4 | -0.0292134 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0287872 |
| RPS25 | ribosomal protein S25 | -0.0287631 |
| RPL11 | ribosomal protein L11 | -0.0286275 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0283261 |
| RPS3 | ribosomal protein S3 | -0.0253625 |
| ANXA2 | annexin A2 | -0.0251074 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0246469 |
| FAM13A | family with sequence similarity 13, member A | -0.02264 |
| OGA | O-GlcNAcase | -0.0211922 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0187965 |
| EGFR | epidermal growth factor receptor | -0.0173003 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0170132 |
| PKM | pyruvate kinase, muscle | -0.0158676 |
| GPC6 | glypican 6 | -0.0155656 |
| RPL12 | ribosomal protein L12 | -0.0154388 |
| PRKCA | protein kinase C, alpha | -0.0137132 |
| RPL26 | ribosomal protein L26 | -0.0136461 |
| NDRG1 | N-myc downstream regulated 1 | -0.0136413 |
| BPTF | bromodomain PHD finger transcription factor | -0.0133412 |
| RPL37A | ribosomal protein L37a | -0.0131613 |
| LDHA | lactate dehydrogenase A | -0.011787 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0104218 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00797629 |
| RPS8 | ribosomal protein S8 | -0.0039214 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.00363693 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.00346298 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.00153738 |
| RPL37 | ribosomal protein L37 | -5.4928E-4 |
