| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.185114 |
| COL3A1 | collagen, type III, alpha 1 | 0.127843 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.101273 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0952603 |
| COL5A2 | collagen, type V, alpha 2 | 0.0843301 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0774148 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0707283 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0703942 |
| ENO1 | enolase 1, (alpha) | 0.0701341 |
| CALR | calreticulin | 0.0690124 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0682196 |
| HDAC9 | histone deacetylase 9 | 0.0675506 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0639693 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.05881 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0571096 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.056468 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0542782 |
| DST | dystonin | 0.0538252 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0501101 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0497287 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.049396 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0483631 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0477117 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0472278 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0467833 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0456265 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0452925 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.044833 |
| SMYD3 | SET and MYND domain containing 3 | 0.0429761 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0428834 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0428756 |
| COL1A2 | collagen, type I, alpha 2 | 0.0421681 |
| NF1 | neurofibromin 1 | 0.0414425 |
| TMSB4X | thymosin beta 4, X-linked | 0.0407262 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0394989 |
| CALU | calumenin | 0.0391098 |
| ANXA1 | annexin A1 | 0.0389051 |
| XPO1 | exportin 1 | 0.0387013 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0385286 |
| GLG1 | golgi glycoprotein 1 | 0.0382822 |
| PTK2 | protein tyrosine kinase 2 | 0.0381929 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0381807 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0380695 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0377036 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0371419 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0366517 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0360729 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.03553 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0353797 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0351976 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0343679 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0341999 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0340361 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.033663 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0331168 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328317 |
| CANX | calnexin | 0.0327046 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0326484 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0326009 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0324538 |
| NRDC | nardilysin convertase | 0.0321094 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0320775 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0320443 |
| NOP58 | NOP58 ribonucleoprotein | 0.0320183 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0320133 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0318285 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0317792 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0317159 |
| CLTC | clathrin, heavy chain (Hc) | 0.0312289 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0303227 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0300906 |
| TPR | translocated promoter region, nuclear basket protein | 0.0299924 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0295348 |
| H1-0 | H1.0 linker histone | 0.029451 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0291777 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.029031 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0286856 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.0285081 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0284662 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0283439 |
| LDHA | lactate dehydrogenase A | 0.0283017 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0280711 |
| MEMO1 | mediator of cell motility 1 | 0.0280332 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0278002 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0277483 |
| WWC2 | WW and C2 domain containing 2 | 0.0276774 |
| ANO6 | anoctamin 6 | 0.0275416 |
| NTM | neurotrimin | 0.0272439 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0271558 |
| CDC73 | cell division cycle 73 | 0.0270284 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0266895 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0266658 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0265837 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0265651 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0265179 |
| TPX2 | TPX2, microtubule-associated | 0.0264985 |
| MB21D2 | Mab-21 domain containing 2 | 0.0263976 |
| SET | SET nuclear proto-oncogene | 0.026302 |
| EZR | ezrin | 0.0261896 |
| GANAB | glucosidase, alpha; neutral AB | 0.0261722 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.0977754 |
| VIM | vimentin | -0.0816427 |
| PTMA | prothymosin, alpha | -0.0769959 |
| TMSB10 | thymosin beta 10 | -0.0674049 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0669351 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0597707 |
| ACTG1 | actin gamma 1 | -0.0551223 |
| RPL35A | ribosomal protein L35a | -0.0525629 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0517657 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0491606 |
| MAP4 | microtubule-associated protein 4 | -0.0475375 |
| PFN1 | profilin 1 | -0.0464623 |
| CENPF | centromere protein F, 350/400kDa | -0.0452594 |
| RPL37 | ribosomal protein L37 | -0.0451397 |
| PLPP1 | phospholipid phosphatase 1 | -0.0437945 |
| RPS8 | ribosomal protein S8 | -0.0430559 |
| FTL | ferritin, light polypeptide | -0.0430025 |
| RPS27A | ribosomal protein S27a | -0.0421135 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0416235 |
| ITGAV | integrin, alpha V | -0.0415754 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0393397 |
| RPS6 | ribosomal protein S6 | -0.0392755 |
| GNAS | GNAS complex locus | -0.0384516 |
| RPS16 | ribosomal protein S16 | -0.037873 |
| RBM25 | RNA binding motif protein 25 | -0.0378483 |
| FOXP2 | forkhead box P2 | -0.0370073 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0369762 |
| RPS12 | ribosomal protein S12 | -0.0360354 |
| AFF1 | AF4/FMR2 family, member 1 | -0.035429 |
| TOX | thymocyte selection-associated high mobility group box | -0.0352054 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0348816 |
| RPL31 | ribosomal protein L31 | -0.0337012 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0334441 |
| EPHA5 | EPH receptor A5 | -0.0333435 |
| CCDC138 | coiled-coil domain containing 138 | -0.0326999 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0325774 |
| RPS25 | ribosomal protein S25 | -0.0318574 |
| RTN4 | reticulon 4 | -0.0316948 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0313754 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0313169 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0303668 |
| SYT1 | synaptotagmin I | -0.0303208 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0302331 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0288708 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.028822 |
| PHIP | pleckstrin homology domain interacting protein | -0.0284563 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | -0.0284192 |
| RPS11 | ribosomal protein S11 | -0.0284113 |
| CCN2 | cellular communication network factor 2 | -0.0277085 |
| PLCB4 | phospholipase C, beta 4 | -0.0271709 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0268398 |
| FBXO11 | F-box protein 11 | -0.0263565 |
| H3-3B | H3.3 histone B | -0.0262601 |
| RPL19 | ribosomal protein L19 | -0.0261848 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0261415 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0258287 |
| DSTN | destrin (actin depolymerizing factor) | -0.0256863 |
| BBX | bobby sox homolog (Drosophila) | -0.0256571 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.025483 |
| DEK | DEK proto-oncogene | -0.0254621 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0252611 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0251867 |
| HMGA1 | high mobility group AT-hook 1 | -0.0251227 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250651 |
| RPS13 | ribosomal protein S13 | -0.0250207 |
| FAM171B | family with sequence similarity 171, member B | -0.0249693 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.024964 |
| RPL5 | ribosomal protein L5 | -0.0249326 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0249263 |
| RPL9 | ribosomal protein L9 | -0.0248187 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0248008 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0246131 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0244274 |
| HMGB1 | high mobility group box 1 | -0.0239488 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0239453 |
| SPAG9 | sperm associated antigen 9 | -0.023878 |
| TENM3 | teneurin transmembrane protein 3 | -0.023789 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0236915 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | -0.0236093 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0235026 |
| PALLD | palladin, cytoskeletal associated protein | -0.0234646 |
| RPS20 | ribosomal protein S20 | -0.0233909 |
| EAPP | E2F-associated phosphoprotein | -0.0233729 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0232572 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0231524 |
| FOXO3 | forkhead box O3 | -0.0230732 |
| RPS24 | ribosomal protein S24 | -0.0230338 |
| RPS29 | ribosomal protein S29 | -0.0226543 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0225936 |
| APOE | apolipoprotein E | -0.0225825 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0223777 |
| RPL30 | ribosomal protein L30 | -0.0223125 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.022277 |
| UBC | ubiquitin C | -0.0220842 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0220079 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0218561 |
| PDGFC | platelet derived growth factor C | -0.0218459 |
| REST | RE1-silencing transcription factor | -0.0218101 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.02151 |
| SLC36A4 | solute carrier family 36 (proton/amino acid symporter), member 4 | -0.0214557 |
