| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | 0.195741 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.179953 |
| HDAC9 | histone deacetylase 9 | 0.142292 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.140926 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.138942 |
| VIM | vimentin | 0.121478 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.113651 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.103091 |
| ADM | adrenomedullin | 0.0993984 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0955358 |
| SQSTM1 | sequestosome 1 | 0.094111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0899144 |
| ANXA2 | annexin A2 | 0.0866382 |
| AHNAK | AHNAK nucleoprotein | 0.0860136 |
| NAV2 | neuron navigator 2 | 0.0836597 |
| CANX | calnexin | 0.0827805 |
| RND3 | Rho family GTPase 3 | 0.0814201 |
| IER3 | immediate early response 3 | 0.0807273 |
| B2M | beta-2-microglobulin | 0.0798356 |
| MT2A | metallothionein 2A | 0.0796094 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0777198 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0738727 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.07342 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0729475 |
| LDHA | lactate dehydrogenase A | 0.070162 |
| SFTPA2 | surfactant protein A2 | 0.0700159 |
| ENO1 | enolase 1, (alpha) | 0.0697996 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0668872 |
| VCAN | versican | 0.0668019 |
| CALR | calreticulin | 0.0657928 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0655231 |
| GOLGB1 | golgin B1 | 0.0628474 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0600278 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0596507 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0594823 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.059438 |
| CD44 | CD44 molecule (Indian blood group) | 0.0592058 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0591143 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0572938 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0566993 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0563726 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0559836 |
| JUN | jun proto-oncogene | 0.0557271 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.052654 |
| ARRDC3 | arrestin domain containing 3 | 0.0512201 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0505199 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0493236 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0492814 |
| RPL23 | ribosomal protein L23 | 0.0492044 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0486596 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0480469 |
| JMJD1C | jumonji domain containing 1C | 0.0477637 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0477619 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0469865 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0459898 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0452672 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.044997 |
| IRF1 | interferon regulatory factor 1 | 0.0442902 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0428302 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0415605 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.040301 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.04011 |
| GOLGA4 | golgin A4 | 0.0396454 |
| ANXA1 | annexin A1 | 0.0385561 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0384616 |
| CRY1 | cryptochrome circadian clock 1 | 0.0383134 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0380345 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0361548 |
| FMNL2 | formin-like 2 | 0.0359483 |
| HLA-E | major histocompatibility complex, class I, E | 0.0358445 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0351006 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0350614 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0349958 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0349367 |
| SPAG9 | sperm associated antigen 9 | 0.0344038 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0343965 |
| KIAA1217 | KIAA1217 | 0.034285 |
| FAM107B | family with sequence similarity 107, member B | 0.0340291 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.033798 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0337713 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0337236 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0336906 |
| STC1 | stanniocalcin 1 | 0.0335688 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0329757 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0312651 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0312285 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0301637 |
| BRD2 | bromodomain containing 2 | 0.0300597 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.030032 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0299911 |
| FNIP1 | folliculin interacting protein 1 | 0.0298671 |
| MORF4L2 | mortality factor 4 like 2 | 0.0298529 |
| RPL19 | ribosomal protein L19 | 0.0297374 |
| RPL26 | ribosomal protein L26 | 0.0290222 |
| RPL14 | ribosomal protein L14 | 0.0288872 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286535 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0286201 |
| SNX9 | sorting nexin 9 | 0.0285298 |
| TKT | transketolase | 0.0284774 |
| GANAB | glucosidase, alpha; neutral AB | 0.0283263 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | -0.146603 |
| FN1 | fibronectin 1 | -0.0850201 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0800848 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0715818 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0664761 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0643784 |
| BICC1 | BicC family RNA binding protein 1 | -0.0613291 |
| DST | dystonin | -0.0586557 |
| VCL | vinculin | -0.0528268 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0472516 |
| HMGA2 | high mobility group AT-hook 2 | -0.0472096 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0460582 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0427775 |
| GLIS3 | GLIS family zinc finger 3 | -0.0413085 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0406511 |
| RAI14 | retinoic acid induced 14 | -0.0401339 |
| DIAPH2 | diaphanous-related formin 2 | -0.0394299 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0392324 |
| SMYD3 | SET and MYND domain containing 3 | -0.0385693 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0384888 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0362583 |
| NAV1 | neuron navigator 1 | -0.0351358 |
| ACTG1 | actin gamma 1 | -0.03507 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0343898 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0343161 |
| TPM1 | tropomyosin 1 (alpha) | -0.0340446 |
| PDE10A | phosphodiesterase 10A | -0.0331231 |
| RTN4 | reticulon 4 | -0.0326216 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0323289 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0320309 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0317512 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0311576 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.030425 |
| CTSD | cathepsin D | -0.0304238 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0301844 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0301257 |
| MSN | moesin | -0.0295149 |
| KLHL24 | kelch-like family member 24 | -0.0287031 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0285686 |
| EGFR | epidermal growth factor receptor | -0.0283201 |
| PLPP6 | phospholipid phosphatase 6 | -0.028038 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.027805 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0277146 |
| EGR1 | early growth response 1 | -0.0271681 |
| TAPBP | TAP binding protein (tapasin) | -0.025995 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0259687 |
| COL1A1 | collagen, type I, alpha 1 | -0.0239708 |
| NABP1 | nucleic acid binding protein 1 | -0.0236609 |
| TENM2 | teneurin transmembrane protein 2 | -0.0233413 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0230638 |
| ZNF292 | zinc finger protein 292 | -0.0230596 |
| FBXO32 | F-box protein 32 | -0.0230149 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0229857 |
| PALLD | palladin, cytoskeletal associated protein | -0.0228307 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0226754 |
| LRRC7 | leucine rich repeat containing 7 | -0.0219282 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0219169 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0217864 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0214115 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0213499 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.021336 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.021209 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0210614 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.020791 |
| PRR16 | proline rich 16 | -0.0204946 |
| NCKAP5 | NCK-associated protein 5 | -0.0202967 |
| MAGED1 | melanoma antigen family D1 | -0.0202283 |
| NF1 | neurofibromin 1 | -0.0200287 |
| RAD51B | RAD51 paralog B | -0.0198275 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0194497 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0193988 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0193191 |
| BNC2 | basonuclin 2 | -0.0188293 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0187509 |
| PHIP | pleckstrin homology domain interacting protein | -0.018691 |
| MMP12 | matrix metallopeptidase 12 | -0.0184339 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0183134 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0182866 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0181669 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0181273 |
| C3 | complement component 3 | -0.018072 |
| RIGI | RNA sensor RIG-I | -0.0180252 |
| MED13L | mediator complex subunit 13-like | -0.0179381 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0179028 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0176675 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0176461 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0175484 |
| CLMP | CXADR-like membrane protein | -0.0175386 |
| CAB39 | calcium binding protein 39 | -0.0175191 |
| RNF24 | ring finger protein 24 | -0.0175128 |
| STC2 | stanniocalcin 2 | -0.0175018 |
| WASF1 | WAS protein family, member 1 | -0.0174838 |
| ATG10 | autophagy related 10 | -0.0172858 |
| CENPF | centromere protein F, 350/400kDa | -0.0171182 |
| CALD1 | caldesmon 1 | -0.0170135 |
| GPATCH8 | G patch domain containing 8 | -0.0168731 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.0168092 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.016796 |
| FMN1 | formin 1 | -0.0165996 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0164042 |
