| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.141294 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103564 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0527626 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0515674 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0482026 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0463037 |
| GOLGA4 | golgin A4 | 0.0461948 |
| ADM | adrenomedullin | 0.0453091 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0444895 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0418633 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0396548 |
| RPS6 | ribosomal protein S6 | 0.0387174 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0382337 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0371167 |
| B2M | beta-2-microglobulin | 0.0364882 |
| CALR | calreticulin | 0.0361732 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0360263 |
| FTL | ferritin, light polypeptide | 0.0356887 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0323757 |
| CANX | calnexin | 0.0311634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0300554 |
| NDRG1 | N-myc downstream regulated 1 | 0.0282888 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0279884 |
| NOP58 | NOP58 ribonucleoprotein | 0.0275082 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0271709 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0270861 |
| PTGES2 | prostaglandin E synthase 2 | 0.0270831 |
| SRP54 | signal recognition particle 54kDa | 0.0268063 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0267176 |
| RPS12 | ribosomal protein S12 | 0.0266301 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0266249 |
| FNIP1 | folliculin interacting protein 1 | 0.0265907 |
| CLINT1 | clathrin interactor 1 | 0.0262303 |
| RPL34 | ribosomal protein L34 | 0.0260155 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0258852 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0258699 |
| COG6 | component of oligomeric golgi complex 6 | 0.0258038 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0256748 |
| INSIG2 | insulin induced gene 2 | 0.0253965 |
| RPS8 | ribosomal protein S8 | 0.0253907 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0253153 |
| GOLGB1 | golgin B1 | 0.0249939 |
| ARRDC3 | arrestin domain containing 3 | 0.0246218 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0245452 |
| SQSTM1 | sequestosome 1 | 0.0243075 |
| COG5 | component of oligomeric golgi complex 5 | 0.0239506 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0233966 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0233653 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0233382 |
| COPA | coatomer protein complex, subunit alpha | 0.023288 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0232534 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0231699 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0231377 |
| RPL11 | ribosomal protein L11 | 0.0229283 |
| MTDH | metadherin | 0.0224909 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0222622 |
| RPL23 | ribosomal protein L23 | 0.0222114 |
| PGM3 | phosphoglucomutase 3 | 0.0219723 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0218911 |
| RPL35A | ribosomal protein L35a | 0.021652 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0215541 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0214838 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0212057 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0210334 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0206982 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0203162 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | 0.0202299 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0196376 |
| INSIG1 | insulin induced gene 1 | 0.0196249 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0196079 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0195281 |
| CADM1 | cell adhesion molecule 1 | 0.0194873 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0194702 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0193866 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0191844 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0189951 |
| ANKRD17 | ankyrin repeat domain 17 | 0.018887 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0188524 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0187352 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0184399 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0183163 |
| INTS6 | integrator complex subunit 6 | 0.0182584 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0182219 |
| RPL12 | ribosomal protein L12 | 0.0181817 |
| WDR43 | WD repeat domain 43 | 0.0181693 |
| RYBP | RING1 and YY1 binding protein | 0.0181127 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0179663 |
| VEGFA | vascular endothelial growth factor A | 0.0178176 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | 0.0177831 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0173098 |
| FUS | FUS RNA binding protein | 0.0172112 |
| KLHDC10 | kelch domain containing 10 | 0.0170922 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0170665 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0170207 |
| PRKCE | protein kinase C, epsilon | 0.01686 |
| ATF4 | activating transcription factor 4 | 0.0168269 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0167829 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0165036 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.016386 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0162723 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.283933 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.165497 |
| COL6A3 | collagen, type VI, alpha 3 | -0.152162 |
| VIM | vimentin | -0.136264 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.120766 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.117955 |
| COL1A1 | collagen, type I, alpha 1 | -0.108981 |
| LOX | lysyl oxidase | -0.108762 |
| TMSB10 | thymosin beta 10 | -0.105744 |
| COL1A2 | collagen, type I, alpha 2 | -0.102452 |
| PRSS23 | protease, serine, 23 | -0.0930046 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.091459 |
| MT2A | metallothionein 2A | -0.0902189 |
| POTEF | POTE ankyrin domain family, member F | -0.0842448 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0823261 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0794999 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0724701 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0705595 |
| GLIS3 | GLIS family zinc finger 3 | -0.0660443 |
| MT1X | metallothionein 1X | -0.0654748 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0632225 |
| TPM4 | tropomyosin 4 | -0.0620708 |
| MAP1B | microtubule-associated protein 1B | -0.0610073 |
| AHNAK | AHNAK nucleoprotein | -0.0608937 |
| LOXL2 | lysyl oxidase-like 2 | -0.0598052 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0581875 |
| HMGA2 | high mobility group AT-hook 2 | -0.0551053 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0540633 |
| CDH13 | cadherin 13 | -0.0524245 |
| TPM1 | tropomyosin 1 (alpha) | -0.0515229 |
| TNS3 | tensin 3 | -0.0512694 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0509199 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0500642 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0484811 |
| CALD1 | caldesmon 1 | -0.048412 |
| CDK6 | cyclin-dependent kinase 6 | -0.0478046 |
| CD44 | CD44 molecule (Indian blood group) | -0.0474997 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0467067 |
| VCL | vinculin | -0.0464565 |
| UBC | ubiquitin C | -0.0464086 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0463671 |
| COL5A1 | collagen, type V, alpha 1 | -0.0454841 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0452985 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0448558 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0445208 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0445174 |
| RTN4 | reticulon 4 | -0.0442881 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0421502 |
| CALU | calumenin | -0.0418178 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0416858 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0394705 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0390992 |
| FAM20C | family with sequence similarity 20, member C | -0.0389914 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0389703 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0384339 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0383274 |
| NAV1 | neuron navigator 1 | -0.0372499 |
| ENO1 | enolase 1, (alpha) | -0.0370873 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0367698 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0366229 |
| ACTG1 | actin gamma 1 | -0.0365942 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0365299 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0362693 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0358886 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0345633 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0338579 |
| TMSB4X | thymosin beta 4, X-linked | -0.03346 |
| HLA-B | major histocompatibility complex, class I, B | -0.0333811 |
| GRB10 | growth factor receptor-bound protein 10 | -0.033064 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0329048 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0325243 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0322444 |
| EGFR | epidermal growth factor receptor | -0.032107 |
| HIP1 | huntingtin interacting protein 1 | -0.0320599 |
| STC1 | stanniocalcin 1 | -0.0319485 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0308549 |
| CLIC4 | chloride intracellular channel 4 | -0.030534 |
| RAI14 | retinoic acid induced 14 | -0.0303901 |
| SRPK2 | SRSF protein kinase 2 | -0.0294424 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0292731 |
| COL5A2 | collagen, type V, alpha 2 | -0.0290903 |
| ASPH | aspartate beta-hydroxylase | -0.0290484 |
| TXNIP | thioredoxin interacting protein | -0.0290009 |
| GSE1 | Gse1 coiled-coil protein | -0.0285628 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0285498 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0283396 |
| PRELID2 | PRELI domain containing 2 | -0.028275 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0282489 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0281833 |
| SEPTIN7 | septin 7 | -0.0281737 |
| EXT1 | exostosin glycosyltransferase 1 | -0.02788 |
| ATXN1 | ataxin 1 | -0.0276897 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0273989 |
| PGK1 | phosphoglycerate kinase 1 | -0.0272256 |
| CCNI | cyclin I | -0.027008 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0269805 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0269019 |
| ANXA5 | annexin A5 | -0.0268191 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0267532 |
| SMAD3 | SMAD family member 3 | -0.0267311 |
