| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | EX229 perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the EX229_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.154217 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.107157 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.102467 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0791732 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0787294 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0725637 |
| INTS6 | integrator complex subunit 6 | 0.0649491 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0634463 |
| ANXA1 | annexin A1 | 0.0585302 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.058389 |
| ASPH | aspartate beta-hydroxylase | 0.0571044 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0569665 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.056873 |
| DTNA | dystrobrevin, alpha | 0.0568291 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0555452 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0542066 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0541114 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0524909 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0501684 |
| SQSTM1 | sequestosome 1 | 0.0463196 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0458763 |
| TXNRD1 | thioredoxin reductase 1 | 0.0409804 |
| RPS12 | ribosomal protein S12 | 0.0409559 |
| SET | SET nuclear proto-oncogene | 0.0404576 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0401555 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0398933 |
| ENO1 | enolase 1, (alpha) | 0.0397047 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0388835 |
| GOLGA4 | golgin A4 | 0.0385846 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0381552 |
| RPL23 | ribosomal protein L23 | 0.0381123 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0374373 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0371164 |
| RPL26 | ribosomal protein L26 | 0.0360848 |
| B2M | beta-2-microglobulin | 0.0348227 |
| BRD2 | bromodomain containing 2 | 0.0343082 |
| RPL37A | ribosomal protein L37a | 0.0339424 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0334849 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0333635 |
| RACK1 | receptor for activated C kinase 1 | 0.0332518 |
| RPS17 | ribosomal protein S17 | 0.0327819 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0314707 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.0304912 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0302882 |
| ADM | adrenomedullin | 0.0301679 |
| RPL9 | ribosomal protein L9 | 0.0300912 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0300233 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0296181 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0295892 |
| RPS3 | ribosomal protein S3 | 0.0284369 |
| CLTC | clathrin, heavy chain (Hc) | 0.0282232 |
| RRBP1 | ribosome binding protein 1 | 0.0280093 |
| IPO7 | importin 7 | 0.027721 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0276315 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0276075 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0275658 |
| CALR | calreticulin | 0.0274939 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0273236 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0273036 |
| GPATCH2L | G patch domain containing 2-like | 0.0272964 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0269286 |
| SEC24A | SEC24 family member A | 0.0267945 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0265727 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0265698 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0262815 |
| MATR3 | matrin 3 | 0.0260489 |
| FNIP1 | folliculin interacting protein 1 | 0.0260181 |
| RUNX1 | runt-related transcription factor 1 | 0.0258021 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0257441 |
| NAV3 | neuron navigator 3 | 0.0256296 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0254062 |
| TTC19 | tetratricopeptide repeat domain 19 | 0.0253128 |
| CANX | calnexin | 0.0253092 |
| MSN | moesin | 0.0247461 |
| CEP250 | centrosomal protein 250kDa | 0.0246995 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0244206 |
| NOP58 | NOP58 ribonucleoprotein | 0.0243882 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0243405 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0238046 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0234357 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0233569 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0233397 |
| CCDC47 | coiled-coil domain containing 47 | 0.0233298 |
| COPA | coatomer protein complex, subunit alpha | 0.0232705 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0229734 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0228957 |
| RPL12 | ribosomal protein L12 | 0.0228519 |
| RPS8 | ribosomal protein S8 | 0.0228217 |
| PCBP2 | poly(rC) binding protein 2 | 0.0226307 |
| SFTPA2 | surfactant protein A2 | 0.0223647 |
| ANXA5 | annexin A5 | 0.0217439 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0216573 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0216207 |
| FUS | FUS RNA binding protein | 0.0214675 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.021458 |
| KIF21A | kinesin family member 21A | 0.0214217 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0213664 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0211173 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0211055 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0210886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.114132 |
| TMSB10 | thymosin beta 10 | -0.0972669 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0958877 |
| VIM | vimentin | -0.0938351 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0899298 |
| RORA | RAR-related orphan receptor A | -0.0762994 |
| HMGA2 | high mobility group AT-hook 2 | -0.0758624 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0697209 |
| LDHA | lactate dehydrogenase A | -0.0688968 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.068527 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0650486 |
| PRKCA | protein kinase C, alpha | -0.0647245 |
| DST | dystonin | -0.0642847 |
| NDRG1 | N-myc downstream regulated 1 | -0.0596841 |
| ATM | ATM serine/threonine kinase | -0.0596553 |
| ATXN1 | ataxin 1 | -0.058877 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0584309 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0580993 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0566401 |
| DNER | delta/notch-like EGF repeat containing | -0.0548736 |
| AHNAK | AHNAK nucleoprotein | -0.0546143 |
| IGF2 | insulin-like growth factor 2 | -0.0535247 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0515587 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0509854 |
| RAI14 | retinoic acid induced 14 | -0.0500775 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0495978 |
| FMN1 | formin 1 | -0.0490675 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0487931 |
| ZNF609 | zinc finger protein 609 | -0.048526 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0481711 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0474672 |
| EFNA5 | ephrin-A5 | -0.0464456 |
| ACTG1 | actin gamma 1 | -0.0461129 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0458894 |
| TPM4 | tropomyosin 4 | -0.0451682 |
| YBX3 | Y box binding protein 3 | -0.0451342 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0449507 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0445974 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0443714 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0433997 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0431462 |
| CD44 | CD44 molecule (Indian blood group) | -0.0429126 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0425556 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0416059 |
| LMO7 | LIM domain 7 | -0.0412292 |
| MYO9B | myosin IXB | -0.0403673 |
| PYGL | phosphorylase, glycogen, liver | -0.0397885 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0387949 |
| RNF213 | ring finger protein 213 | -0.0385941 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0384484 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0383487 |
| NALCN | sodium leak channel, non selective | -0.0364932 |
| SMYD3 | SET and MYND domain containing 3 | -0.0364882 |
| POTEF | POTE ankyrin domain family, member F | -0.0363372 |
| NF1 | neurofibromin 1 | -0.0359519 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0358113 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0357657 |
| TMEM123 | transmembrane protein 123 | -0.0356537 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0352812 |
| THBS1 | thrombospondin 1 | -0.0351644 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.035023 |
| DENND5B | DENN/MADD domain containing 5B | -0.0349209 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0339378 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.033922 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.033753 |
| PRR16 | proline rich 16 | -0.0336885 |
| VCL | vinculin | -0.0335063 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0333598 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0332453 |
| NAV2 | neuron navigator 2 | -0.032357 |
| PTMA | prothymosin, alpha | -0.0322266 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0317956 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0313547 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0313155 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0312002 |
| FLNB | filamin B, beta | -0.0311493 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0303297 |
| PODXL | podocalyxin-like | -0.0296719 |
| CDCP1 | CUB domain containing protein 1 | -0.0294181 |
| CCDC91 | coiled-coil domain containing 91 | -0.0293604 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0287724 |
| RIN2 | Ras and Rab interactor 2 | -0.0287101 |
| RIGI | RNA sensor RIG-I | -0.0283398 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0281481 |
| COL5A1 | collagen, type V, alpha 1 | -0.0281051 |
| CAVIN1 | caveolae associated protein 1 | -0.0280074 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0275739 |
| NBEA | neurobeachin | -0.0274106 |
| SUMF1 | sulfatase modifying factor 1 | -0.0269762 |
| RAD51B | RAD51 paralog B | -0.0267186 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0264935 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0264645 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0264199 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0259632 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0257821 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0255821 |
| SVIL | supervillin | -0.025433 |
| CAPRIN2 | caprin family member 2 | -0.0252323 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0250533 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0249133 |
