EXO1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description exonuclease 1|This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9156)
Similar Terms
Downloads & Tools

Genes

318 genes differentially expressed following the EXO1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
OR14A16 olfactory receptor, family 14, subfamily A, member 16 2.83166
ASB12 ankyrin repeat and SOCS box containing 12 2.83166
RBM24 RNA binding motif protein 24 2.83166
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 2.83166
KLF9 Kruppel-like factor 9 2.83166
MSX2 msh homeobox 2 2.83166
S100Z S100 calcium binding protein Z 2.83166
DUSP10 dual specificity phosphatase 10 2.83166
GCSAML germinal center-associated, signaling and motility-like 2.83166
ANGPTL7 angiopoietin-like 7 2.83166
RNF222 ring finger protein 222 2.83166
PIRT phosphoinositide-interacting regulator of transient receptor potential channels 2.83166
IZUMO3 IZUMO family member 3 2.83166
TBC1D3L TBC1 domain family, member 3L 2.83166
CFAP53 cilia and flagella associated protein 53 2.83166
TAS2R31 taste receptor, type 2, member 31 2.83166
HLA-DMB major histocompatibility complex, class II, DM beta 2.83166
GRM6 glutamate receptor, metabotropic 6 2.83166
CD22 CD22 molecule 2.83166
TMEM86A transmembrane protein 86A 2.83166
TUBA3D tubulin, alpha 3d 2.83166
CEP164 centrosomal protein 164kDa 2.83166
TMIGD1 transmembrane and immunoglobulin domain containing 1 2.83166
NNMT nicotinamide N-methyltransferase 2.83166
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 2.75232
NCKAP1L NCK-associated protein 1-like 2.75232
TPSD1 tryptase delta 1 2.75232
LRRC55 leucine rich repeat containing 55 2.75232
MUC5B mucin 5B, oligomeric mucus/gel-forming 2.75232
PDE7B phosphodiesterase 7B 2.75232
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.75232
ASPA aspartoacylase 2.75232
DIRAS2 DIRAS family, GTP-binding RAS-like 2 2.75232
GPR22 G protein-coupled receptor 22 2.75232
MYOM3 myomesin 3 2.75232
HEXB hexosaminidase B (beta polypeptide) 2.75232
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 2.75232
SYCE3 synaptonemal complex central element protein 3 2.75232
TAS2R13 taste receptor, type 2, member 13 2.75232
LGALS2 lectin, galactoside-binding, soluble, 2 2.75232
CLCN1 chloride channel, voltage-sensitive 1 2.75232
TMC8 transmembrane channel-like 8 2.75232
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 2.75232
LUZP4 leucine zipper protein 4 2.75232
FAM110D family with sequence similarity 110, member D 2.75232
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 2.75232
DIO3 deiodinase, iodothyronine, type III 2.75232
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.75232
RPL3L ribosomal protein L3-like 2.75232
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.75232
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 2.75232
TMEM89 transmembrane protein 89 2.75232
LDHC lactate dehydrogenase C 2.75232
SOWAHB sosondowah ankyrin repeat domain family member B 2.75232
DLL4 delta-like 4 (Drosophila) 2.75232
LRRC63 leucine rich repeat containing 63 2.75232
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 2.75232
MBLAC1 metallo-beta-lactamase domain containing 1 2.75232
CCDC194 coiled-coil domain containing 194 2.75232
GATA2 GATA binding protein 2 2.75232
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.75232
TUBA4B tubulin, alpha 4b 2.75232
COX8C cytochrome c oxidase subunit VIIIC 2.75232
LGSN lengsin, lens protein with glutamine synthetase domain 2.75232
TAS1R1 taste receptor, type 1, member 1 2.75232
SAA1 serum amyloid A1 2.75232
EXOC3L4 exocyst complex component 3-like 4 2.75232
PIWIL3 piwi-like RNA-mediated gene silencing 3 2.75232
VSIG2 V-set and immunoglobulin domain containing 2 2.75232
LY6K lymphocyte antigen 6 complex, locus K 2.75232
OOSP4B oocyte secreted protein family member 4B 2.75232
GREP1 glycine rich extracellular protein 1 2.75232
MYMK myomaker, myoblast fusion factor 2.75232
DEFB131B defensin beta 131B 2.75232
PLAAT4 phospholipase A and acyltransferase 4 2.75232
FYB1 FYN binding protein 1 2.75232
CCER2 coiled-coil glutamate-rich protein 2 2.75232
FCMR Fc fragment of IgM receptor 2.75232
LY6H lymphocyte antigen 6 complex, locus H 2.75232
C1QL2 complement component 1, q subcomponent-like 2 2.75232
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.75232
MUTYH mutY homolog 2.75232
CLEC12A C-type lectin domain family 12, member A 2.75232
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) 2.75232
MS4A4E membrane-spanning 4-domains, subfamily A, member 4E 2.75232
RPS4X ribosomal protein S4, X-linked 2.75232
SLC46A2 solute carrier family 46, member 2 2.75232
GNLY granulysin 2.75232
SPINK1 serine peptidase inhibitor, Kazal type 1 2.75232
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.75232
FOXQ1 forkhead box Q1 2.75232
LAPTM5 lysosomal protein transmembrane 5 2.75232
LDHAL6B lactate dehydrogenase A-like 6B 2.75232
CKM creatine kinase, muscle 2.75232
RHOXF2 Rhox homeobox family, member 2 2.75232
RAB44 RAB44, member RAS oncogene family 2.75232
RS1 retinoschisin 1 2.75232
OR2A7 olfactory receptor, family 2, subfamily A, member 7 2.75232
KLHL34 kelch-like family member 34 2.75232
CFHR3 complement factor H-related 3 2.75232
OR5P3 olfactory receptor, family 5, subfamily P, member 3 2.75232
RAX retina and anterior neural fold homeobox 2.75232
GOLGA8K golgin A8 family, member K 2.75232
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.75232
FAM209A family with sequence similarity 209, member A 2.75232
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 2.75232
TRIM55 tripartite motif containing 55 2.75232
HUS1B HUS1 checkpoint homolog b (S. pombe) 2.75232
TDRD10 tudor domain containing 10 2.75232
OAZ3 ornithine decarboxylase antizyme 3 2.75232
CLRN2 clarin 2 2.75232
MZB1 marginal zone B and B1 cell-specific protein 2.75232
DSCC1 DNA replication and sister chromatid cohesion 1 2.75232
C11ORF91 chromosome 11 open reading frame 91 2.75232
LYG2 lysozyme G-like 2 2.75232
TNF tumor necrosis factor 2.75232
LRTM2 leucine-rich repeats and transmembrane domains 2 2.75232
CT55 cancer/testis antigen 55 2.75232
EREG epiregulin 2.75232
CABP5 calcium binding protein 5 2.75232
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein 2.75232
MUCL1 mucin-like 1 2.75232
ETV3L ets variant 3-like 2.75232
LAMB4 laminin, beta 4 2.75232
PCDHAC1 protocadherin alpha subfamily C, 1 2.75232
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 2.75232
IGIP IgA-inducing protein 2.75232
TMEM31 transmembrane protein 31 2.75232
VAV1 vav 1 guanine nucleotide exchange factor 2.75232
TP63 tumor protein p63 2.75232
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3 2.75232
ZC3H12D zinc finger CCCH-type containing 12D 2.75232
BEAN1 brain expressed, associated with NEDD4, 1 2.75232
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.75232
TTC16 tetratricopeptide repeat domain 16 2.75232
HRCT1 histidine rich carboxyl terminus 1 2.75232
COL17A1 collagen, type XVII, alpha 1 2.75232
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 2.75232
SHISA8 shisa family member 8 2.75232
MBOAT4 membrane bound O-acyltransferase domain containing 4 2.75232
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.75232
IL17B interleukin 17B 2.75232
TGM4 transglutaminase 4 2.75232
SPNS3 spinster homolog 3 (Drosophila) 2.75232
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 2.75232
THEM5 thioesterase superfamily member 5 2.75232
IFI16 interferon, gamma-inducible protein 16 2.75232
DAND5 DAN domain family member 5, BMP antagonist 2.75232
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 2.75232
LRRC39 leucine rich repeat containing 39 2.75232
TSKS testis-specific serine kinase substrate 2.75232
RTN4RL1 reticulon 4 receptor-like 1 2.75232
GPR171 G protein-coupled receptor 171 2.75232
CHAT choline O-acetyltransferase 2.75232
PRCD progressive rod-cone degeneration 2.75232
IRX4 iroquois homeobox 4 2.75232
LYSMD4 LysM, putative peptidoglycan-binding, domain containing 4 2.75232
TSPAN32 tetraspanin 32 2.75232
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 2.75232
STEAP4 STEAP family member 4 2.75232
ZNF679 zinc finger protein 679 2.75232
DHRS7C dehydrogenase/reductase (SDR family) member 7C 2.75232
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.75232
CCDC166 coiled-coil domain containing 166 2.75232
GHRH growth hormone releasing hormone 2.75232
DCST2 DC-STAMP domain containing 2 2.75232
SPINT4 serine peptidase inhibitor, Kunitz type 4 2.75232
ASCL3 achaete-scute family bHLH transcription factor 3 2.75232
EPN3 epsin 3 2.75232
COL18A1 collagen, type XVIII, alpha 1 2.70343
ZNF382 zinc finger protein 382 2.68123
HSBP1 heat shock factor binding protein 1 2.66371
RPS19 ribosomal protein S19 2.6485
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 2.64238
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.60462
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.58125
MAML2 mastermind-like 2 (Drosophila) 2.50531
MOSPD1 motile sperm domain containing 1 2.49057
FBXL15 F-box and leucine-rich repeat protein 15 2.49057
ZNF383 zinc finger protein 383 2.48808
SLC39A12 solute carrier family 39 (zinc transporter), member 12 2.42461
ACTMAP actin maturation protease 2.3895
SYN1 synapsin I 2.38527
DLAT dihydrolipoamide S-acetyltransferase 2.36164
DEPTOR DEP domain containing MTOR-interacting protein 2.31944
TMIGD3 transmembrane and immunoglobulin domain containing 3 2.31944
CCDC107 coiled-coil domain containing 107 2.31078
PRRC2C proline-rich coiled-coil 2C 2.2793
CORO7 coronin 7 2.2793
TROAP trophinin associated protein 2.26385
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor 2.25837
FGF19 fibroblast growth factor 19 2.24412
LETM2 leucine zipper-EF-hand containing transmembrane protein 2 2.22433
TTC9C tetratricopeptide repeat domain 9C 2.22278
FSHR follicle stimulating hormone receptor 2.21028
MED24 mediator complex subunit 24 2.21028
CALHM6 calcium homeostasis modulator family member 6 2.18487
TMPO thymopoietin 2.18156
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.18121
EVA1B eva-1 homolog B (C. elegans) 2.16831
RBM18 RNA binding motif protein 18 2.16335
C21ORF91 chromosome 21 open reading frame 91 2.16068
UBAP2 ubiquitin associated protein 2 2.15493
MYLIP myosin regulatory light chain interacting protein 2.15213
STRAP serine/threonine kinase receptor associated protein 2.1211
NRP2 neuropilin 2 2.09829
MATN1 matrilin 1, cartilage matrix protein 2.09441
CLPSL1 colipase-like 1 2.09393
PRICKLE3 prickle homolog 3 (Drosophila) 2.06976
CISD3 CDGSH iron sulfur domain 3 2.04967
ANO8 anoctamin 8 2.02592
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.01608
RICTOR RPTOR independent companion of MTOR, complex 2 2.01307
MTRES1 mitochondrial transcription rescue factor 1 2.01307
BICD1 bicaudal D homolog 1 (Drosophila) 2.00649

decreased expression

Symbol Name Standardized Value
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.83166
MMP19 matrix metallopeptidase 19 -2.83166
CD101 CD101 molecule -2.83166
DUOX1 dual oxidase 1 -2.83166
THSD8 thrombospondin type 1 domain containing 8 -2.75232
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.75232
SFTPD surfactant protein D -2.75232
CPB2 carboxypeptidase B2 (plasma) -2.75232
COL15A1 collagen, type XV, alpha 1 -2.75232
LRTM3 leucine rich repeat transmembrane protein 3 -2.75232
CRYGB crystallin, gamma B -2.75232
MDH1B malate dehydrogenase 1B, NAD (soluble) -2.75232
LOC105378220 macrophage receptor MARCO-like -2.75232
SPDYE2B speedy/RINGO cell cycle regulator family member E2B -2.75232
TMPRSS15 transmembrane protease, serine 15 -2.75232
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -2.75232
SPOCD1 SPOC domain containing 1 -2.75232
QRFPR pyroglutamylated RFamide peptide receptor -2.75232
DUSP13B dual specificity phosphatase 13B -2.75232
C20ORF204 chromosome 20 open reading frame 204 -2.75232
H2AC4 H2A clustered histone 4 -2.75232
NEMP2 nuclear envelope integral membrane protein 2 -2.75232
NTAQ1 N-terminal glutamine amidase 1 -2.75232
MYL10 myosin, light chain 10, regulatory -2.75232
COL13A1 collagen, type XIII, alpha 1 -2.75232
METTL6 methyltransferase like 6 -2.75232
CCDC121 coiled-coil domain containing 121 -2.75232
C1QL3 complement component 1, q subcomponent-like 3 -2.75232
MYH13 myosin, heavy chain 13, skeletal muscle -2.75232
PLEKHG7 pleckstrin homology domain containing, family G (with RhoGef domain) member 7 -2.75232
SLC16A11 solute carrier family 16, member 11 -2.75232
CLCNKB chloride channel, voltage-sensitive Kb -2.75232
SNTN sentan, cilia apical structure protein -2.75232
NEK5 NIMA-related kinase 5 -2.75232
MKRN2 makorin ring finger protein 2 -2.75232
HLA-DOB major histocompatibility complex, class II, DO beta -2.75232
C17ORF99 chromosome 17 open reading frame 99 -2.75232
ZFP92 ZFP92 zinc finger protein -2.75232
SVOP SV2 related protein homolog (rat) -2.75232
C10ORF105 chromosome 10 open reading frame 105 -2.75232
FCRLB Fc receptor-like B -2.75232
ACSS1 acyl-CoA synthetase short-chain family member 1 -2.75232
NUTM2G NUT family member 2G -2.75232
CCDC78 coiled-coil domain containing 78 -2.75232
NR1D1 nuclear receptor subfamily 1, group D, member 1 -2.75232
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -2.75232
KLHL6 kelch-like family member 6 -2.75232
DRC8 dynein regulatory complex subunit 8 -2.73596
KIF11 kinesin family member 11 -2.6732
KDM7A lysine (K)-specific demethylase 7A -2.65323
DOCK4 dedicator of cytokinesis 4 -2.61793
NIPAL1 NIPA-like domain containing 1 -2.6118
C1ORF122 chromosome 1 open reading frame 122 -2.60462
MYO15A myosin XVA -2.60462
ANGPT2 angiopoietin 2 -2.60462
ARL15 ADP-ribosylation factor-like 15 -2.50531
ZDHHC2 zinc finger, DHHC-type containing 2 -2.50504
STX12 syntaxin 12 -2.4745
SEC62 SEC62 homolog (S. cerevisiae) -2.47261
RFX2 regulatory factor X, 2 (influences HLA class II expression) -2.45258
C5 complement component 5 -2.43685
LPAR6 lysophosphatidic acid receptor 6 -2.39938
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase -2.39611
GPR3 G protein-coupled receptor 3 -2.38125
CCDC184 coiled-coil domain containing 184 -2.36164
FER fer (fps/fes related) tyrosine kinase -2.36164
IGSF1 immunoglobulin superfamily, member 1 -2.34366
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.33913
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -2.333
ZNF865 zinc finger protein 865 -2.32697
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2 -2.31944
LARP1 La ribonucleoprotein domain family, member 1 -2.26021
ANAPC11 anaphase promoting complex subunit 11 -2.26002
OSBP oxysterol binding protein -2.23592
MOXD1 monooxygenase, DBH-like 1 -2.22433
CLIP3 CAP-GLY domain containing linker protein 3 -2.21028
GALM galactose mutarotase (aldose 1-epimerase) -2.20354
PPM1J protein phosphatase, Mg2+/Mn2+ dependent, 1J -2.19147
ARGLU1 arginine and glutamate rich 1 -2.19147
VMA12 vacuolar ATPase assembly factor VMA12 -2.18487
RGS22 regulator of G-protein signaling 22 -2.15213
CLHC1 clathrin heavy chain linker domain containing 1 -2.15126
OGN osteoglycin -2.14109
C5ORF47 chromosome 5 open reading frame 47 -2.1331
C6ORF89 chromosome 6 open reading frame 89 -2.1331
QRICH2 glutamine rich 2 -2.13305
STON1 stonin 1 -2.12215
NT5C3A 5'-nucleotidase, cytosolic IIIA -2.1211
C10ORF88 chromosome 10 open reading frame 88 -2.10304
ARHGEF37 Rho guanine nucleotide exchange factor (GEF) 37 -2.08317
SNX19 sorting nexin 19 -2.04967
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 -2.02592
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -2.02425
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.02408
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -2.01307
ACIN1 apoptotic chromatin condensation inducer 1 -2.01307
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -2.01307
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) -2.01307
YIPF4 Yip1 domain family, member 4 -2.01192
DCAF15 DDB1 and CUL4 associated factor 15 -2.00907
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 -2.00466
EGF epidermal growth factor -2.00466
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 -2.00152