EXO1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description exonuclease 1|This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 9156)
External Link http://www.ncbi.nlm.nih.gov/gene/9156
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195 interacting proteins for EXO1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABLIM1 actin binding LIM protein 1
ADCY8 adenylate cyclase 8 (brain)
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
AMPD2 adenosine monophosphate deaminase 2
APOA2 apolipoprotein A-II
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAD BCL2-associated agonist of cell death
BAIAP2 BAI1-associated protein 2
BLM Bloom syndrome, RecQ helicase-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C6ORF48 chromosome 6 open reading frame 48
CAMKK1 calcium/calmodulin-dependent protein kinase kinase 1, alpha
CANX calnexin
CAPNS1 calpain, small subunit 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC6 coiled-coil domain containing 6
CDC25C cell division cycle 25C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CEP170 centrosomal protein 170kDa
CEP170B centrosomal protein 170B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
CLCA1 chloride channel accessory 1
CLINT1 clathrin interactor 1
CLTCL1 clathrin, heavy chain-like 1
CRTC2 CREB regulated transcription coactivator 2
CRTC3 CREB regulated transcription coactivator 3
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYLD cylindromatosis (turban tumor syndrome)
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DENND1A DENN/MADD domain containing 1A
DENND4A DENN/MADD domain containing 4A
DENND4C DENN/MADD domain containing 4C
DMTN dematin actin binding protein
DOCK11 dedicator of cytokinesis 11
E2F1 E2F transcription factor 1
EDC3 enhancer of mRNA decapping 3
EIF4E2 eukaryotic translation initiation factor 4E family member 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FOXO3 forkhead box O3
GAPVD1 GTPase activating protein and VPS9 domains 1
GIGYF1 GRB10 interacting GYF protein 1
GIGYF2 GRB10 interacting GYF protein 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GRIP1 glutamate receptor interacting protein 1
GRN granulin
H2AFX H2A histone family, member X
HAX1 HCLS1 associated protein X-1
HCLS1 hematopoietic cell-specific Lyn substrate 1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HNF4A hepatocyte nuclear factor 4, alpha
HSPA1B heat shock 70kDa protein 1B
HSPA7 heat shock 70kDa protein 7 (HSP70B)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
IRS2 insulin receptor substrate 2
IRS4 insulin receptor substrate 4
KIAA0355 KIAA0355
KIAA0930 KIAA0930
KIAA1671 KIAA1671
KIF1B kinesin family member 1B
KIF1C kinesin family member 1C
KLC2 kinesin light chain 2
KLC4 kinesin light chain 4
KPNA4 karyopherin alpha 4 (importin alpha 3)
KPNB1 karyopherin (importin) beta 1
KSR1 kinase suppressor of ras 1
LARP1 La ribonucleoprotein domain family, member 1
LIMA1 LIM domain and actin binding 1
LIN7C lin-7 homolog C (C. elegans)
LMO7 LIM domain 7
LUZP1 leucine zipper protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK2 MAP/microtubule affinity-regulating kinase 2
MARK3 MAP/microtubule affinity-regulating kinase 3
MAST2 microtubule associated serine/threonine kinase 2
MAX MYC associated factor X
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MTMR12 myotubularin related protein 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
NADK NAD kinase
NAV1 neuron navigator 1
NCKAP1 NCK-associated protein 1
NCKIPSD NCK interacting protein with SH3 domain
NELFA negative elongation factor complex member A
NELFB negative elongation factor complex member B
NF1 neurofibromin 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARP8 poly (ADP-ribose) polymerase family, member 8
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCNA proliferating cell nuclear antigen
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB2 pleckstrin homology-like domain, family B, member 2
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKP2 plakophilin 2
PLEKHA5 pleckstrin homology domain containing, family A member 5
PLEKHA7 pleckstrin homology domain containing, family A member 7
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP2R5D protein phosphatase 2, regulatory subunit B', delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSAP prosaposin
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PUM1 pumilio RNA-binding family member 1
R3HDM1 R3H domain containing 1
R3HDM2 R3H domain containing 2
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASAL2 RAS protein activator like 2
RBBP8 retinoblastoma binding protein 8
REEP4 receptor accessory protein 4
RICTOR RPTOR independent companion of MTOR, complex 2
RPA2 replication protein A2, 32kDa
RTKN rhotekin
RYK receptor-like tyrosine kinase
SACK1B scaffolding CK1 anchoring protein B
SAMD4A sterile alpha motif domain containing 4A
SAMD4B sterile alpha motif domain containing 4B
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SFN stratifin
SH3PXD2A SH3 and PX domains 2A
SH3RF1 SH3 domain containing ring finger 1
SH3RF3 SH3 domain containing ring finger 3
SHKBP1 SH3KBP1 binding protein 1
SHROOM3 shroom family member 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SORBS1 sorbin and SH3 domain containing 1
SORBS2 sorbin and SH3 domain containing 2
SQRDL sulfide quinone reductase-like (yeast)
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STK3 serine/threonine kinase 3
SUMO2 small ubiquitin-like modifier 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D22A TBC1 domain family, member 22A
TBC1D22B TBC1 domain family, member 22B
TBC1D4 TBC1 domain family, member 4
TBC1D5 TBC1 domain family, member 5
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TIAM1 T-cell lymphoma invasion and metastasis 1
TJP1 tight junction protein 1
TJP3 tight junction protein 3
TMOD3 tropomodulin 3 (ubiquitous)
TP53BP2 tumor protein p53 binding protein 2
TPD52L1 tumor protein D52-like 1
TPM3 tropomyosin 3
TRIM32 tripartite motif containing 32
TSC2 tuberous sclerosis 2
TTC28 tetratricopeptide repeat domain 28
UBC ubiquitin C
UHRF1BP1L UHRF1 binding protein 1-like
USP54 ubiquitin specific peptidase 54
USP8 ubiquitin specific peptidase 8
VIPAS39 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
VPS33B vacuolar protein sorting 33 homolog B (yeast)
WFS1 Wolfram syndrome 1 (wolframin)
WNK1 WNK lysine deficient protein kinase 1
WSB1 WD repeat and SOCS box containing 1
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XPO1 exportin 1
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZCCHC8 zinc finger, CCHC domain containing 8
ZFP36L2 ZFP36 ring finger protein-like 2