EYA3 Gene Set

Dataset DEPOD Substrates of Phosphatases
Category physical interactions
Type phosphatase
Description EYA transcriptional coactivator and phosphatase 3|This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 2140)
External Link http://www.koehn.embl.de/depod/showp.php?gene=EYA3
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2 substrates of the phosphatase EYA3 from the curated DEPOD Substrates of Phosphatases dataset.

Symbol Name
H2AFX H2A histone family, member X
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa