EYA3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description EYA transcriptional coactivator and phosphatase 3|This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 2140)
External Link http://www.ncbi.nlm.nih.gov/gene/2140
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Genes

11 interacting proteins for EYA3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATM ATM serine/threonine kinase
CDK2 cyclin-dependent kinase 2
DACH1 dachshund family transcription factor 1
H2AFX H2A histone family, member X
SIX1 SIX homeobox 1
SIX2 SIX homeobox 2
SIX4 SIX homeobox 4
SIX5 SIX homeobox 5
SKI SKI proto-oncogene
UBC ubiquitin C
ZDHHC17 zinc finger, DHHC-type containing 17