| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | enhancer of zeste 2 polycomb repressive complex 2 subunit|This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 2146) |
| External Link | https://ncbi.nlm.nih.gov/gene/2146 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the EZH2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.0104917 |
| CD200 | CD200 molecule | 0.00898639 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00860836 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00787231 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00711558 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.00692368 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.00683124 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00664422 |
| MAGEA3 | melanoma antigen family A3 | 0.00644526 |
| RNASET2 | ribonuclease T2 | 0.00642351 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00637621 |
| CHEK2 | checkpoint kinase 2 | 0.00619473 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.00595127 |
| ATP9A | ATPase, class II, type 9A | 0.0058241 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00581228 |
| HOXC6 | homeobox C6 | 0.00579701 |
| MAGEA12 | melanoma antigen family A12 | 0.00579674 |
| MT1H | metallothionein 1H | 0.00579115 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | 0.00572406 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 0.00570684 |
| SPRR3 | small proline-rich protein 3 | 0.00561927 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00561021 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.00559385 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | 0.00554657 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0055219 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.00550054 |
| GUCY2C | guanylate cyclase 2C | 0.00541859 |
| CP | ceruloplasmin (ferroxidase) | 0.00535538 |
| MT2A | metallothionein 2A | 0.00533549 |
| CD53 | CD53 molecule | 0.00533194 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00533047 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00532858 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00532416 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00527075 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00525499 |
| KLK6 | kallikrein-related peptidase 6 | 0.00524529 |
| CTSB | cathepsin B | 0.00521783 |
| GSTZ1 | glutathione S-transferase zeta 1 | 0.00520366 |
| MYO5C | myosin VC | 0.00519981 |
| SELL | selectin L | 0.00519157 |
| MXRA7 | matrix-remodelling associated 7 | 0.00509342 |
| KRT23 | keratin 23, type I | 0.00504552 |
| UXT | ubiquitously-expressed, prefoldin-like chaperone | 0.00504088 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00503311 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.00499982 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.00497924 |
| H1-0 | H1.0 linker histone | 0.0049776 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.00494171 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 0.00493749 |
| MT1X | metallothionein 1X | 0.00487433 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00485692 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00484624 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 | 0.00482394 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00481602 |
| VWA8 | von Willebrand factor A domain containing 8 | 0.00478212 |
| RBM47 | RNA binding motif protein 47 | 0.00475789 |
| PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.00475522 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00473554 |
| RESF1 | retroelement silencing factor 1 | 0.00473177 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 | 0.00464717 |
| LYZ | lysozyme | 0.00463838 |
| ZNF586 | zinc finger protein 586 | 0.00462935 |
| CD93 | CD93 molecule | 0.00462405 |
| NXT2 | nuclear transport factor 2-like export factor 2 | 0.00461993 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 | 0.00461527 |
| MGST3 | microsomal glutathione S-transferase 3 | 0.0046045 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein | 0.00459968 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.00458412 |
| ITM2C | integral membrane protein 2C | 0.00458056 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 | 0.0045722 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.00456766 |
| LUM | lumican | 0.00454494 |
| PLK1 | polo-like kinase 1 | 0.00454483 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 | 0.00452909 |
| LYPLA1 | lysophospholipase I | 0.00452847 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 0.0044943 |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 | 0.00449094 |
| HAUS4 | HAUS augmin-like complex, subunit 4 | 0.00448601 |
| TRIM22 | tripartite motif containing 22 | 0.00447493 |
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.00446663 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.00446563 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.00446456 |
| MAOB | monoamine oxidase B | 0.00445935 |
| PCNA | proliferating cell nuclear antigen | 0.00444834 |
| PEG3 | paternally expressed 3 | 0.00442716 |
| SMAGP | small cell adhesion glycoprotein | 0.00441941 |
| TRAF3IP2 | TRAF3 interacting protein 2 | 0.00440328 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.00438631 |
| INSR | insulin receptor | 0.00438542 |
| ZNF443 | zinc finger protein 443 | 0.00438024 |
| SETBP1 | SET binding protein 1 | 0.004352 |
| PLIN3 | perilipin 3 | 0.00435116 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 0.00434198 |
| RTP4 | receptor (chemosensory) transporter protein 4 | 0.00433513 |
| MT1G | metallothionein 1G | 0.00432309 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00431053 |
| MGP | matrix Gla protein | 0.0043095 |
| NDRG2 | NDRG family member 2 | 0.00430768 |
| SLC35A5 | solute carrier family 35, member A5 | 0.00428338 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00426675 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.00426509 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00425979 |
| CLDN10 | claudin 10 | 0.00424243 |
| MRPL19 | mitochondrial ribosomal protein L19 | 0.00423052 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.0042243 |
| SIRT3 | sirtuin 3 | 0.00422372 |
| PURA | purine-rich element binding protein A | 0.00422104 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00420396 |
| GPX2 | glutathione peroxidase 2 | 0.00418685 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00416997 |
| GRAMD2B | GRAM domain containing 2B | 0.00416696 |
| ASRGL1 | asparaginase like 1 | 0.00416668 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | 0.00416368 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00415343 |
| PFDN4 | prefoldin subunit 4 | 0.00414546 |
| MMP12 | matrix metallopeptidase 12 | 0.00414387 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.00414103 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00410446 |
| C11ORF71 | chromosome 11 open reading frame 71 | 0.0040717 |
| PIGP | phosphatidylinositol glycan anchor biosynthesis, class P | 0.00404533 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | 0.00402302 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.0040225 |
| PLPP2 | phospholipid phosphatase 2 | 0.0040224 |
| SERINC5 | serine incorporator 5 | 0.00402136 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) | 0.00400033 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00399266 |
| PHF11 | PHD finger protein 11 | 0.00399177 |
| LACTB2 | lactamase, beta 2 | 0.00398692 |
| ERGIC2 | ERGIC and golgi 2 | 0.00398164 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.00397703 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.00396727 |
| LMNB1 | lamin B1 | 0.0039657 |
| ICAM3 | intercellular adhesion molecule 3 | 0.00395283 |
| PTGES | prostaglandin E synthase | 0.00395107 |
| HEPH | hephaestin | 0.0039414 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00393424 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.00393266 |
| SNX10 | sorting nexin 10 | 0.00393105 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00391257 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00391102 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00390038 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.00389226 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00388946 |
| TBL1X | transducin (beta)-like 1X-linked | 0.00388589 |
| KBTBD2 | kelch repeat and BTB (POZ) domain containing 2 | 0.00387508 |
| TBXA2R | thromboxane A2 receptor | 0.00387324 |
| MRPS28 | mitochondrial ribosomal protein S28 | 0.00387141 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog | 0.003869 |
| MMP9 | matrix metallopeptidase 9 | 0.00386072 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00384321 |
| PRKAG1 | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 0.00383517 |
| ELF1 | E74-like factor 1 (ets domain transcription factor) | 0.00382267 |
| NNMT | nicotinamide N-methyltransferase | 0.00381458 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.00380427 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00379115 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0037875 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00378106 |
| KRT18 | keratin 18, type I | 0.00377793 |
| NME5 | NME/NM23 family member 5 | 0.00377283 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00376141 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.0037609 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00375434 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00375332 |
| C1S | complement component 1, s subcomponent | 0.00374736 |
| MUC16 | mucin 16, cell surface associated | 0.00374083 |
| GSAP | gamma-secretase activating protein | 0.00373284 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00373278 |
| MPZL2 | myelin protein zero-like 2 | 0.00372387 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00371703 |
| CTSZ | cathepsin Z | 0.00371128 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00370417 |
| PEX2 | peroxisomal biogenesis factor 2 | 0.00369799 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 | 0.00369366 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.00369277 |
| AMPH | amphiphysin | 0.00368986 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00368926 |
| MT1F | metallothionein 1F | 0.00368196 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.00367986 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.00367823 |
| VEZF1 | vascular endothelial zinc finger 1 | 0.0036766 |
| NREP | neuronal regeneration related protein | 0.00366326 |
| THYN1 | thymocyte nuclear protein 1 | 0.00365802 |
| TPM4 | tropomyosin 4 | 0.00364366 |
| ERG | v-ets avian erythroblastosis virus E26 oncogene homolog | 0.00362934 |
| METRN | meteorin, glial cell differentiation regulator | 0.00362246 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.00362245 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00362226 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.0036194 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00360535 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | 0.00359992 |
| KLF9 | Kruppel-like factor 9 | 0.00359653 |
| RBMX | RNA binding motif protein, X-linked | 0.00358845 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00358379 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.00357676 |
| NEK7 | NIMA-related kinase 7 | 0.00357184 |
| F8 | coagulation factor VIII, procoagulant component | 0.00356062 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | 0.00355468 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 | 0.00355097 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00355019 |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.00354938 |
| PRKCH | protein kinase C, eta | 0.0035492 |
| CCL15 | chemokine (C-C motif) ligand 15 | 0.00354638 |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) | 0.00354141 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00353337 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.00353147 |
| IL6R | interleukin 6 receptor | 0.0035295 |
| ESD | esterase D | 0.00352447 |
| CD69 | CD69 molecule | 0.00351637 |
| MCTS1 | malignant T cell amplified sequence 1 | 0.00351365 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00350492 |
| C8ORF33 | chromosome 8 open reading frame 33 | 0.00350198 |
| IER2 | immediate early response 2 | 0.00349764 |
| PRKCA | protein kinase C, alpha | 0.00349491 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00349482 |
| KLK10 | kallikrein-related peptidase 10 | 0.00349025 |
| FAM172A | family with sequence similarity 172, member A | 0.00348979 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00347805 |
| SLC46A3 | solute carrier family 46, member 3 | 0.0034773 |
| TLE4 | transducin-like enhancer of split 4 | 0.00347488 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.00346895 |
| XAF1 | XIAP associated factor 1 | 0.00346737 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00346707 |
| TSPAN5 | tetraspanin 5 | 0.00346147 |
| HIST3H2A | histone cluster 3, H2a | 0.00345392 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.00345358 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | 0.0034514 |
| IMPA1 | inositol(myo)-1(or 4)-monophosphatase 1 | 0.00344929 |
| SRGN | serglycin | 0.00344924 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.00344802 |
| MARCKSL1 | MARCKS-like 1 | 0.00344705 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 | 0.00344584 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein | 0.00344378 |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.00344339 |
| CD9 | CD9 molecule | 0.00344191 |
| NFIB | nuclear factor I/B | 0.00343776 |
| ZBTB10 | zinc finger and BTB domain containing 10 | 0.00343037 |
| VAMP5 | vesicle-associated membrane protein 5 | 0.00342945 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.0034261 |
| VBP1 | von Hippel-Lindau binding protein 1 | 0.00341014 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00340525 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00340499 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | 0.00340267 |
| USP18 | ubiquitin specific peptidase 18 | 0.00339787 |
| CUL4B | cullin 4B | 0.00339673 |
| NPTX2 | neuronal pentraxin II | 0.00339593 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.00339289 |
| TMEM243 | transmembrane protein 243, mitochondrial | 0.00337304 |
| RBM7 | RNA binding motif protein 7 | 0.00336891 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00336821 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | -0.0111449 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00885083 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.00825563 |
| NVL | nuclear VCP-like | -0.00790458 |
| TUBB2A | tubulin, beta 2A class IIa | -0.00734577 |
| GPX3 | glutathione peroxidase 3 | -0.00728401 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.00715373 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00698558 |
| CDC25B | cell division cycle 25B | -0.0069259 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.00678626 |
| CYBRD1 | cytochrome b reductase 1 | -0.00671963 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00667707 |
| MAP7 | microtubule-associated protein 7 | -0.00651989 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00648597 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00641948 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00641121 |
| GLS | glutaminase | -0.00624186 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -0.00622232 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00622165 |
| SDC1 | syndecan 1 | -0.00617078 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00614732 |
| LTF | lactotransferrin | -0.00612452 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.00608064 |
| KRT7 | keratin 7, type II | -0.0060149 |
| COL9A2 | collagen, type IX, alpha 2 | -0.00598173 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00592933 |
| CLGN | calmegin | -0.00569607 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00569471 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00545074 |
| KRT81 | keratin 81, type II | -0.00540893 |
| CPE | carboxypeptidase E | -0.00522387 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00521673 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.00519762 |
| TUBA4A | tubulin, alpha 4a | -0.00518912 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.00514206 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00511465 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00510026 |
| BLVRB | biliverdin reductase B | -0.00510023 |
| IPO13 | importin 13 | -0.00508024 |
| TUBB6 | tubulin, beta 6 class V | -0.00503883 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.0050356 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00501626 |
| THBS1 | thrombospondin 1 | -0.00501437 |
| CLDN1 | claudin 1 | -0.00494337 |
| PLXNB2 | plexin B2 | -0.00491658 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0048836 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00482094 |
| COCH | cochlin | -0.00480103 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00477272 |
| NXN | nucleoredoxin | -0.0047676 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00474766 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00470535 |
| VNN1 | vanin 1 | -0.00468472 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00468141 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00466678 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00463638 |
| CES1 | carboxylesterase 1 | -0.00463462 |
| SGCE | sarcoglycan, epsilon | -0.00457054 |
| HMOX1 | heme oxygenase 1 | -0.00453494 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | -0.00451804 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | -0.00448574 |
| PLXNC1 | plexin C1 | -0.00448445 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 | -0.00448435 |
| CAMP | cathelicidin antimicrobial peptide | -0.00447648 |
| PLK2 | polo-like kinase 2 | -0.00446723 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | -0.0044616 |
| STC1 | stanniocalcin 1 | -0.00445127 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00442273 |
| CD52 | CD52 molecule | -0.00437553 |
| POSTN | periostin, osteoblast specific factor | -0.00434708 |
| TGFB1 | transforming growth factor, beta 1 | -0.00434482 |
| S100A14 | S100 calcium binding protein A14 | -0.00434185 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.00433476 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.004317 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00429033 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.00427996 |
| CDK11A | cyclin-dependent kinase 11A | -0.00427442 |
| MLPH | melanophilin | -0.00425913 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00423866 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00421208 |
| MEIS2 | Meis homeobox 2 | -0.00421101 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00420868 |
| CDV3 | CDV3 homolog (mouse) | -0.0041902 |
| STK38 | serine/threonine kinase 38 | -0.00418962 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | -0.00418953 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -0.00418806 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00415021 |
| S100A9 | S100 calcium binding protein A9 | -0.00414333 |
| TLN1 | talin 1 | -0.00413897 |
| WDR26 | WD repeat domain 26 | -0.00409045 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -0.0040829 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00407172 |
| OGFRL1 | opioid growth factor receptor-like 1 | -0.00405435 |
| GPC3 | glypican 3 | -0.00402808 |
| FAM117A | family with sequence similarity 117, member A | -0.00400614 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00400161 |
| S100A7 | S100 calcium binding protein A7 | -0.00399161 |
| PGC | progastricsin (pepsinogen C) | -0.00397349 |
| HPSE | heparanase | -0.0039688 |
| CALML5 | calmodulin-like 5 | -0.00395891 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.00393952 |
| FGL2 | fibrinogen-like 2 | -0.00393251 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | -0.00392583 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00392166 |
| SFN | stratifin | -0.00391889 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.00389781 |
| IDE | insulin-degrading enzyme | -0.00388596 |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 | -0.00388261 |
| CLCA2 | chloride channel accessory 2 | -0.00388067 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00387775 |
| ABHD4 | abhydrolase domain containing 4 | -0.00386623 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | -0.00386052 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | -0.00385956 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) | -0.00385065 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00384998 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00383198 |
| CRYAB | crystallin, alpha B | -0.0038317 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00382406 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00382167 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.00381688 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00380082 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00379045 |
| HSPA4 | heat shock 70kDa protein 4 | -0.00379035 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | -0.0037876 |
| DENND1A | DENN/MADD domain containing 1A | -0.0037833 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.00377967 |
| NPY1R | neuropeptide Y receptor Y1 | -0.00375257 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.00375045 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | -0.00375043 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.00373896 |
| PDGFC | platelet derived growth factor C | -0.00373806 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.0037296 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00371927 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.00371633 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00371505 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.00371047 |
| YARS1 | tyrosyl-tRNA synthetase 1 | -0.00369467 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein | -0.00369043 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) | -0.00368727 |
| S100A6 | S100 calcium binding protein A6 | -0.00368335 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00368172 |
| TNNC1 | troponin C type 1 (slow) | -0.00366704 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.00366576 |
| KLK5 | kallikrein-related peptidase 5 | -0.00366207 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.0036481 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.00363779 |
| STXBP2 | syntaxin binding protein 2 | -0.00363762 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00363686 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | -0.00362874 |
| GBP1 | guanylate binding protein 1, interferon-inducible | -0.00362357 |
| FOXE1 | forkhead box E1 | -0.00361966 |
| PER3 | period circadian clock 3 | -0.00361517 |
| LOXL1 | lysyl oxidase-like 1 | -0.00360928 |
| ORC1 | origin recognition complex, subunit 1 | -0.00360391 |
| KYNU | kynureninase | -0.00359763 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00358203 |
| RTN3 | reticulon 3 | -0.0035709 |
| ANXA3 | annexin A3 | -0.00353336 |
| CKM | creatine kinase, muscle | -0.00353255 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00352656 |
| FMO1 | flavin containing monooxygenase 1 | -0.00352352 |
| PTK2B | protein tyrosine kinase 2 beta | -0.00352162 |
| RGS16 | regulator of G-protein signaling 16 | -0.00351959 |
| C5AR1 | complement component 5a receptor 1 | -0.0035179 |
| DHDDS | dehydrodolichyl diphosphate synthase | -0.00351303 |
| UBASH3A | ubiquitin associated and SH3 domain containing A | -0.0035064 |
| DPT | dermatopontin | -0.00350457 |
| RXRA | retinoid X receptor, alpha | -0.00349937 |
| GRB7 | growth factor receptor-bound protein 7 | -0.00349595 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene | -0.00349592 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.00349278 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 | -0.00349225 |
| KRT5 | keratin 5, type II | -0.00348904 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00347469 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | -0.00345298 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00344944 |
| INSM1 | insulinoma-associated 1 | -0.00344326 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.0034383 |
| APOC1 | apolipoprotein C-I | -0.00342568 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00342524 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | -0.00342286 |
| CUL3 | cullin 3 | -0.00342001 |
| REG1A | regenerating islet-derived 1 alpha | -0.00341531 |
| MAP1B | microtubule-associated protein 1B | -0.00341377 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00340674 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00338621 |
| DES | desmin | -0.00338486 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00337401 |
| MAP7D1 | MAP7 domain containing 1 | -0.00337212 |
| DLX2 | distal-less homeobox 2 | -0.00336679 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase | -0.00335467 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00334884 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00334833 |
| HIST1H2BH | histone cluster 1, H2bh | -0.0033479 |
| GSE1 | Gse1 coiled-coil protein | -0.00332891 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.00331825 |
| PHF1 | PHD finger protein 1 | -0.00331034 |
| IER5 | immediate early response 5 | -0.0032935 |
| PON3 | paraoxonase 3 | -0.00329084 |
| ARHGAP4 | Rho GTPase activating protein 4 | -0.00328938 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) | -0.00328878 |
| CDCP1 | CUB domain containing protein 1 | -0.00328767 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -0.0032847 |
| DYSF | dysferlin | -0.00328416 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00328309 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00327872 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00327725 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00327695 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00326903 |
| ANK2 | ankyrin 2, neuronal | -0.00326806 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00326687 |
| SRPK1 | SRSF protein kinase 1 | -0.00326083 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.00325815 |
| EIF5 | eukaryotic translation initiation factor 5 | -0.00325301 |
| EMP3 | epithelial membrane protein 3 | -0.00325237 |
| JAM2 | junctional adhesion molecule 2 | -0.00324576 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.00324447 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | -0.00323313 |
| CTSD | cathepsin D | -0.00323267 |
| HRASLS | HRAS-like suppressor | -0.00323214 |
| ACOT9 | acyl-CoA thioesterase 9 | -0.00323034 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -0.00322666 |
| INSL6 | insulin-like 6 | -0.0032241 |
| LIPF | lipase, gastric | -0.00322062 |
| CD300A | CD300a molecule | -0.00321696 |
| IL10RA | interleukin 10 receptor, alpha | -0.00320572 |
| PIP | prolactin-induced protein | -0.00320547 |
| ZNF395 | zinc finger protein 395 | -0.00320465 |
| SORT1 | sortilin 1 | -0.00320428 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | -0.00320136 |
| CNPY3 | canopy FGF signaling regulator 3 | -0.00319474 |
| CDC20 | cell division cycle 20 | -0.00319301 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00319024 |
| CKAP4 | cytoskeleton-associated protein 4 | -0.00318519 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | -0.003184 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | -0.00318211 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | -0.00318191 |
| CD37 | CD37 molecule | -0.00316663 |
| IL11 | interleukin 11 | -0.00316324 |
| JAG1 | jagged 1 | -0.00316106 |
| FBN2 | fibrillin 2 | -0.00315947 |
| UROD | uroporphyrinogen decarboxylase | -0.00315344 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00315163 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00315018 |
| NPEPL1 | aminopeptidase-like 1 | -0.00314407 |
| POFUT2 | protein O-fucosyltransferase 2 | -0.00314304 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00313911 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00313904 |
