Eclampsia Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A pre-eclampsia characterized by the presence of seizures. (Human Disease Ontology, DOID_13593)
External Link https://www.disgenet.org/browser/0/1/0/C0013537
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Genes

223 genes associated with the disease Eclampsia in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACE angiotensin I converting enzyme
ACKR3 atypical chemokine receptor 3
ACTB actin, beta
ACVR2A activin A receptor, type IIA
ADAM12 ADAM metallopeptidase domain 12
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR2 adiponectin receptor 2
ADM adrenomedullin
ADORA2B adenosine A2b receptor
AFM afamin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALB albumin
ANGPT1 angiopoietin 1
ANXA2 annexin A2
ANXA5 annexin A5
APOE apolipoprotein E
AQP4 aquaporin 4
AQP9 aquaporin 9
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AVP arginine vasopressin
AVPR1A arginine vasopressin receptor 1A
BHLHE40 basic helix-loop-helix family, member e40
BRD2 bromodomain containing 2
C19ORF33 chromosome 19 open reading frame 33
CALR calreticulin
CCL2 chemokine (C-C motif) ligand 2
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CD14 CD14 molecule
CD24 CD24 molecule
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CFAP97 cilia and flagella associated protein 97
CFH complement factor H
CFI complement factor I
CLIC3 chloride intracellular channel 3
COMT catechol-O-methyltransferase
CORIN corin, serine peptidase
COX1
COX2
CRP C-reactive protein, pentraxin-related
CSF1R colony stimulating factor 1 receptor
CTNNA3 catenin (cadherin-associated protein), alpha 3
CUL3 cullin 3
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAP death-associated protein
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DGKI diacylglycerol kinase, iota
DUSP9 dual specificity phosphatase 9
EBAG9 estrogen receptor binding site associated, antigen, 9
EBI3 Epstein-Barr virus induced 3
EDN1 endothelin 1
EDN2 endothelin 2
EGF epidermal growth factor
EIF3E eukaryotic translation initiation factor 3, subunit E
ELF5 E74-like factor 5 (ets domain transcription factor)
ENG endoglin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERVW-1 endogenous retrovirus group W, member 1
ESR1 estrogen receptor 1
F10 coagulation factor X
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
FABP4 fatty acid binding protein 4, adipocyte
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBN2 fibrillin 2
FGFR4 fibroblast growth factor receptor 4
FLNB filamin B, beta
FLT1 fms-related tyrosine kinase 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXP3 forkhead box P3
FSHR follicle stimulating hormone receptor
FST follistatin
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCM1 glial cells missing homolog 1 (Drosophila)
GEM GTP binding protein overexpressed in skeletal muscle
GIP gastric inhibitory polypeptide
GLRX glutaredoxin (thioltransferase)
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTM1 glutathione S-transferase mu 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSPA4 heat shock 70kDa protein 4
HTRA4 HtrA serine peptidase 4
ICA1 islet cell autoantigen 1, 69kDa
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IGF2 insulin-like growth factor 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL10 interleukin 10
IL15 interleukin 15
IL17D interleukin 17D
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL37 interleukin 37
IL4 interleukin 4
IL6 interleukin 6
ILK integrin-linked kinase
INHBA inhibin, beta A
INO80B INO80 complex subunit B
INS insulin
INSR insulin receptor
INTS6 integrator complex subunit 6
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KDR kinase insert domain receptor
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KISS1R KISS1 receptor
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
LEP leptin
LHCGR luteinizing hormone/choriogonadotropin receptor
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
MBL2 mannose-binding lectin (protein C) 2, soluble
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTF1 metal-regulatory transcription factor 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYDGF myeloid-derived growth factor
NECTIN4 nectin cell adhesion molecule 4
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NXF1 nuclear RNA export factor 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAPPA2 pappalysin 2
PAX3 paired box 3
PDCD1 programmed cell death 1
PGF placental growth factor
PLAC1 placenta-specific 1
POTEF POTE ankyrin domain family, member F
PPARG peroxisome proliferator-activated receptor gamma
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PROK1 prokineticin 1
PROS1 protein S (alpha)
PSG5 pregnancy specific beta-1-glycoprotein 5
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RETN resistin
RHD Rh blood group, D antigen
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
S100B S100 calcium binding protein B
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORD sorbitol dehydrogenase
SPATA2 spermatogenesis associated 2
SRY sex determining region Y
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT5A signal transducer and activator of transcription 5A
STOX1 storkhead box 1
SUMO4 small ubiquitin-like modifier 4
SYT1 synaptotagmin I
TAC3 tachykinin 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TXN thioredoxin
UCN urocortin
USO1 USO1 vesicle transport factor
VEGFA vascular endothelial growth factor A
WAS Wiskott-Aldrich syndrome
WASF2 WAS protein family, member 2
WNK1 WNK lysine deficient protein kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase