| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.201615 |
| YBX1 | Y box binding protein 1 | 0.0318949 |
| RPS4X | ribosomal protein S4, X-linked | 0.0292283 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0270606 |
| RPS12 | ribosomal protein S12 | 0.0236977 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0208432 |
| PNN | pinin, desmosome associated protein | 0.0184864 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0182995 |
| EDN1 | endothelin 1 | 0.0174772 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0165145 |
| RPS23 | ribosomal protein S23 | 0.015785 |
| SET | SET nuclear proto-oncogene | 0.0156496 |
| TMEM41B | transmembrane protein 41B | 0.0155305 |
| EPHA6 | EPH receptor A6 | 0.0145095 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.0144962 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0140445 |
| ANKUB1 | ankyrin repeat and ubiquitin domain containing 1 | 0.0138527 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0136974 |
| VCL | vinculin | 0.0131247 |
| PCM1 | pericentriolar material 1 | 0.0130115 |
| BTBD10 | BTB (POZ) domain containing 10 | 0.0125206 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0122208 |
| RACK1 | receptor for activated C kinase 1 | 0.0119808 |
| TBK1 | TANK-binding kinase 1 | 0.0119647 |
| MORF4L2 | mortality factor 4 like 2 | 0.0117445 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.01063 |
| CPOX | coproporphyrinogen oxidase | 0.0104826 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0102871 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0102129 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 | 0.0100159 |
| RPL23 | ribosomal protein L23 | 0.00988031 |
| CRY1 | cryptochrome circadian clock 1 | 0.00962828 |
| RPL21 | ribosomal protein L21 | 0.00951725 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.00949278 |
| OXR1 | oxidation resistance 1 | 0.00948421 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.00943888 |
| MT2A | metallothionein 2A | 0.0094338 |
| CEP95 | centrosomal protein 95kDa | 0.00924517 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0090997 |
| ZSWIM5 | zinc finger, SWIM-type containing 5 | 0.00900508 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.00899323 |
| WDR26 | WD repeat domain 26 | 0.00894172 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.00893637 |
| NEK2 | NIMA-related kinase 2 | 0.0089164 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00883983 |
| RRM2 | ribonucleotide reductase M2 | 0.00882533 |
| CLDND1 | claudin domain containing 1 | 0.00861081 |
| RPS6 | ribosomal protein S6 | 0.0085982 |
| KCTD3 | potassium channel tetramerization domain containing 3 | 0.00856153 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0085478 |
| RAB28 | RAB28, member RAS oncogene family | 0.00851294 |
| PABPC1L | poly(A) binding protein, cytoplasmic 1-like | 0.00851075 |
| FN1 | fibronectin 1 | 0.00849336 |
| EGR1 | early growth response 1 | 0.00845291 |
| NDUFS5 | NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase) | 0.00827841 |
| RPL36 | ribosomal protein L36 | 0.00827224 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | 0.00825309 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.00815753 |
| NUDCD2 | NudC domain containing 2 | 0.00800547 |
| RPL12 | ribosomal protein L12 | 0.0079953 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00793873 |
| NDUFC1 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa | 0.0079236 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00785347 |
| RPS26 | ribosomal protein S26 | 0.0078426 |
| NUMBL | numb homolog (Drosophila)-like | 0.00777006 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00770636 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.00768027 |
| COX20 | COX20 cytochrome c oxidase assembly factor | 0.00757342 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.00756098 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase | 0.00750728 |
| ZNF146 | zinc finger protein 146 | 0.0075072 |
| CEP70 | centrosomal protein 70kDa | 0.00750114 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 | 0.00748206 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.00731782 |
| NOP2 | NOP2 nucleolar protein | 0.00731231 |
| APRT | adenine phosphoribosyltransferase | 0.00729382 |
| SMAD4 | SMAD family member 4 | 0.0072681 |
| FAM120A | family with sequence similarity 120A | 0.00723107 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.00722526 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00720134 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.00709794 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00706798 |
| ZNF251 | zinc finger protein 251 | 0.00696548 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00690904 |
| ROMO1 | reactive oxygen species modulator 1 | 0.00677134 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 0.00676778 |
| INO80E | INO80 complex subunit E | 0.00676661 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.00672628 |
| SIN3A | SIN3 transcription regulator family member A | 0.00671989 |
| MRGBP | MRG/MORF4L binding protein | 0.00671751 |
| TSPYL2 | TSPY-like 2 | 0.00670677 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.0066753 |
| MINK1 | misshapen-like kinase 1 | 0.00662662 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.00661282 |
| ATP5MK | ATP synthase membrane subunit k | 0.00660269 |
| IGF2 | insulin-like growth factor 2 | 0.00660227 |
| KLF9 | Kruppel-like factor 9 | 0.00660034 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | 0.00659775 |
| TTC9C | tetratricopeptide repeat domain 9C | 0.00659135 |
| RTN4 | reticulon 4 | 0.00658861 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.222375 |
| NLGN1 | neuroligin 1 | -0.189351 |
| VIM | vimentin | -0.13999 |
| MMP12 | matrix metallopeptidase 12 | -0.137986 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.121413 |
| DPYD | dihydropyrimidine dehydrogenase | -0.112205 |
| DST | dystonin | -0.110429 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103329 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.102108 |
| PCDH7 | protocadherin 7 | -0.100611 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.100596 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0913107 |
| HMGA2 | high mobility group AT-hook 2 | -0.0877406 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0836347 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0794313 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0776059 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0759361 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0748019 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0725462 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0701696 |
| EHBP1 | EH domain binding protein 1 | -0.0697803 |
| USP34 | ubiquitin specific peptidase 34 | -0.0687735 |
| AHNAK | AHNAK nucleoprotein | -0.0674366 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.066362 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0659517 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0645081 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0643962 |
| RASAL2 | RAS protein activator like 2 | -0.0633063 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0617084 |
| CLDN1 | claudin 1 | -0.0607527 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0600779 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0581334 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0570814 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0570261 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.057009 |
| H1-0 | H1.0 linker histone | -0.0568271 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0565083 |
| ZNF804A | zinc finger protein 804A | -0.0543277 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0513114 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0513045 |
| MGAT4C | MGAT4 family, member C | -0.0511546 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0507921 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0504806 |
| SYT1 | synaptotagmin I | -0.0503939 |
| CARD16 | caspase recruitment domain family, member 16 | -0.05016 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0500356 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0499391 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0499051 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0493811 |
| PARD3 | par-3 family cell polarity regulator | -0.0476642 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0461242 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0460305 |
| NF1 | neurofibromin 1 | -0.0457854 |
| ASPH | aspartate beta-hydroxylase | -0.0456 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0452699 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0441976 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0438498 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0437794 |
| PGK1 | phosphoglycerate kinase 1 | -0.043773 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0434218 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0430493 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0427997 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0426879 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0424902 |
| XPO1 | exportin 1 | -0.0420176 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0417874 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | -0.041039 |
| NEBL | nebulette | -0.0409829 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.040248 |
| FSTL5 | follistatin-like 5 | -0.0401984 |
| YAP1 | Yes-associated protein 1 | -0.0399727 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0396936 |
| TENM3 | teneurin transmembrane protein 3 | -0.0395206 |
| ZNF638 | zinc finger protein 638 | -0.0386742 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0382975 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0381496 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0368291 |
| MED13L | mediator complex subunit 13-like | -0.0367707 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0367263 |
| CMIP | c-Maf inducing protein | -0.036681 |
| CCND1 | cyclin D1 | -0.0365811 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0364944 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0364391 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0362984 |
| CANX | calnexin | -0.0360255 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0359027 |
| BCHE | butyrylcholinesterase | -0.035619 |
| PDGFC | platelet derived growth factor C | -0.0353166 |
| PTK2 | protein tyrosine kinase 2 | -0.0350427 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0350121 |
| HDAC9 | histone deacetylase 9 | -0.0349253 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0347338 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0346892 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0346362 |
| ERBIN | erbb2 interacting protein | -0.0345488 |
| HMGA1 | high mobility group AT-hook 1 | -0.0345303 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0338695 |
| DTNA | dystrobrevin, alpha | -0.0334179 |
| ACTG1 | actin gamma 1 | -0.0331945 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0331049 |
