| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D1 | TSC22 domain family, member 1 | 0.136313 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0919698 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0892209 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0875363 |
| NDRG1 | N-myc downstream regulated 1 | 0.0761918 |
| TXNIP | thioredoxin interacting protein | 0.0668466 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0655526 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0647343 |
| PLIN2 | perilipin 2 | 0.0634026 |
| ENO1 | enolase 1, (alpha) | 0.0567758 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0560721 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0559987 |
| ASPH | aspartate beta-hydroxylase | 0.0506518 |
| DENND4C | DENN/MADD domain containing 4C | 0.0484505 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0477011 |
| LIMA1 | LIM domain and actin binding 1 | 0.0475374 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0467842 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0466593 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0433556 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0432799 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0428475 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0420743 |
| KIF16B | kinesin family member 16B | 0.0409526 |
| RNF149 | ring finger protein 149 | 0.0390013 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0386828 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.037537 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0355049 |
| SSH2 | slingshot protein phosphatase 2 | 0.0354621 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0350155 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0340199 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0339232 |
| SDC1 | syndecan 1 | 0.0333493 |
| MT2A | metallothionein 2A | 0.0332239 |
| MORF4L2 | mortality factor 4 like 2 | 0.0330598 |
| KRT19 | keratin 19, type I | 0.0329826 |
| DNM2 | dynamin 2 | 0.0324188 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.031589 |
| IFNGR1 | interferon gamma receptor 1 | 0.0311448 |
| EPCAM | epithelial cell adhesion molecule | 0.0308928 |
| PTGR1 | prostaglandin reductase 1 | 0.0308353 |
| TMEM123 | transmembrane protein 123 | 0.0307831 |
| PADI1 | peptidyl arginine deiminase, type I | 0.0307633 |
| KRT18 | keratin 18, type I | 0.0306305 |
| PTMA | prothymosin, alpha | 0.0305984 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0305201 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | 0.0301626 |
| APP | amyloid beta (A4) precursor protein | 0.0294411 |
| TMC5 | transmembrane channel-like 5 | 0.0293099 |
| TOB1 | transducer of ERBB2, 1 | 0.0292421 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0291851 |
| HLA-E | major histocompatibility complex, class I, E | 0.0289162 |
| LDHA | lactate dehydrogenase A | 0.0280373 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0265024 |
| SQSTM1 | sequestosome 1 | 0.0264848 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.026321 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0258295 |
| PHF3 | PHD finger protein 3 | 0.025601 |
| PGK1 | phosphoglycerate kinase 1 | 0.025185 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0251365 |
| PAPOLA | poly(A) polymerase alpha | 0.0249479 |
| NIPSNAP2 | nipsnap homolog 2 | 0.02487 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0247915 |
| GRB2 | growth factor receptor-bound protein 2 | 0.0243868 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0243533 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0242173 |
| SFTPA2 | surfactant protein A2 | 0.0241847 |
| MUC20 | mucin 20, cell surface associated | 0.0239105 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0238791 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0236872 |
| CLTC | clathrin, heavy chain (Hc) | 0.0236006 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0233528 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0232084 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0229227 |
| HLA-B | major histocompatibility complex, class I, B | 0.0228078 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0228075 |
| SET | SET nuclear proto-oncogene | 0.0227885 |
| EFNA1 | ephrin-A1 | 0.0226511 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0226487 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0224677 |
| ARRDC3 | arrestin domain containing 3 | 0.0223846 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0223739 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0223082 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0222081 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0221265 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0221053 |
| PRSS3 | protease, serine, 3 | 0.0221023 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.02195 |
| EFNB2 | ephrin-B2 | 0.0218158 |
| AREG | amphiregulin | 0.0216874 |
| ANXA4 | annexin A4 | 0.0216417 |
| ADD3 | adducin 3 (gamma) | 0.0214355 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0212277 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0208258 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0208108 |
| PRSS23 | protease, serine, 23 | 0.0206839 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0206294 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0203965 |
| IL20RA | interleukin 20 receptor, alpha | 0.0202461 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0202141 |
| APOL1 | apolipoprotein L, 1 | 0.020194 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.158553 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.135636 |
| LMO7 | LIM domain 7 | -0.13136 |
| EGR1 | early growth response 1 | -0.122135 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.119389 |
| ANXA2 | annexin A2 | -0.0957016 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0928474 |
| MX2 | MX dynamin-like GTPase 2 | -0.0897346 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0872588 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0860425 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.085036 |
| MX1 | MX dynamin-like GTPase 1 | -0.0809324 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.078525 |
| RNF213 | ring finger protein 213 | -0.078402 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0776044 |
| PLSCR1 | phospholipid scramblase 1 | -0.0771019 |
| CCNL1 | cyclin L1 | -0.0758369 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0757717 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.073392 |
| RIGI | RNA sensor RIG-I | -0.0720742 |
| AHI1 | Abelson helper integration site 1 | -0.0704366 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0646636 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0645499 |
| SP100 | SP100 nuclear antigen | -0.0616396 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0594545 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.059448 |
| VCL | vinculin | -0.0584469 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0575778 |
| ZNF207 | zinc finger protein 207 | -0.050382 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0499906 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0498388 |
| INTS6 | integrator complex subunit 6 | -0.0485112 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0483527 |
| MYO1E | myosin IE | -0.0482859 |
| VMP1 | vacuole membrane protein 1 | -0.0476343 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0474811 |
| TJP1 | tight junction protein 1 | -0.0460412 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0456285 |
| POTEF | POTE ankyrin domain family, member F | -0.0427693 |
| EPHB2 | EPH receptor B2 | -0.0427305 |
| EZR | ezrin | -0.0425569 |
| RPS6 | ribosomal protein S6 | -0.0413882 |
| STK24 | serine/threonine kinase 24 | -0.0413525 |
| SMAD3 | SMAD family member 3 | -0.0409881 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0406688 |
| KIAA1217 | KIAA1217 | -0.0405159 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0403817 |
| HBS1L | HBS1-like translational GTPase | -0.0403699 |
| ACTN4 | actinin, alpha 4 | -0.0400873 |
| PERP | PERP, TP53 apoptosis effector | -0.040003 |
| RUNX1 | runt-related transcription factor 1 | -0.0393197 |
| NCKAP5 | NCK-associated protein 5 | -0.0391014 |
| CLDN4 | claudin 4 | -0.0388562 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0386283 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0385821 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.038403 |
| ATP11A | ATPase, class VI, type 11A | -0.0382707 |
| RPL35A | ribosomal protein L35a | -0.0380722 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0377948 |
| IRF1 | interferon regulatory factor 1 | -0.0377572 |
| NF1 | neurofibromin 1 | -0.0368565 |
| PMP22 | peripheral myelin protein 22 | -0.0368231 |
| TRIM25 | tripartite motif containing 25 | -0.0367703 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0364239 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0358184 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0355314 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0354973 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0354401 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0340548 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0339778 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0336058 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0332912 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0332523 |
| LAP3 | leucine aminopeptidase 3 | -0.0331482 |
| ACTG1 | actin gamma 1 | -0.0328183 |
| ADAR | adenosine deaminase, RNA-specific | -0.0320769 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0318871 |
| BPTF | bromodomain PHD finger transcription factor | -0.0313991 |
| LYZ | lysozyme | -0.0309748 |
| SETX | senataxin | -0.03072 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0305347 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0302361 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.03002 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0298245 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0294645 |
| CD46 | CD46 molecule, complement regulatory protein | -0.029378 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.029369 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0292041 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0291464 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.0289417 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0288627 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0286019 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0283316 |
| MAP7 | microtubule-associated protein 7 | -0.0282985 |
| APOL6 | apolipoprotein L, 6 | -0.028256 |
| OCLN | occludin | -0.027871 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0274786 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0273312 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0272657 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0272539 |
