| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Econazole_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | 0.0718139 |
| IGF2 | insulin-like growth factor 2 | 0.0625217 |
| VCL | vinculin | 0.05715 |
| BCL2L1 | BCL2-like 1 | 0.0335263 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.030289 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0299635 |
| TRIM26 | tripartite motif containing 26 | 0.0297215 |
| A2M | alpha-2-macroglobulin | 0.028852 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0280061 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0247127 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0238511 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0232374 |
| ITGAV | integrin, alpha V | 0.0231146 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0222333 |
| SERINC1 | serine incorporator 1 | 0.0216126 |
| CFB | complement factor B | 0.021545 |
| PLAC8 | placenta-specific 8 | 0.0212651 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0203565 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.01891 |
| SELENOP | selenoprotein P | 0.0186704 |
| VIL1 | villin 1 | 0.0180031 |
| DNAH17 | dynein, axonemal, heavy chain 17 | 0.0178734 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0178255 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0176714 |
| KIF5B | kinesin family member 5B | 0.0176634 |
| SMAD3 | SMAD family member 3 | 0.0163441 |
| APP | amyloid beta (A4) precursor protein | 0.0156087 |
| RSU1 | Ras suppressor protein 1 | 0.0144607 |
| EFNA1 | ephrin-A1 | 0.0144357 |
| MRTFA | myocardin related transcription factor A | 0.0144135 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0143704 |
| AOPEP | aminopeptidase O (putative) | 0.0143117 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0141514 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0139729 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0139021 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0138464 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.013724 |
| DOCK5 | dedicator of cytokinesis 5 | 0.013472 |
| HNMT | histamine N-methyltransferase | 0.0130479 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0129883 |
| RPS27A | ribosomal protein S27a | 0.0124691 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0123496 |
| UBC | ubiquitin C | 0.0123069 |
| ITSN2 | intersectin 2 | 0.0122029 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0120726 |
| PITPNB | phosphatidylinositol transfer protein, beta | 0.0119523 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | 0.0116413 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0115697 |
| HGD | homogentisate 1,2-dioxygenase | 0.0115128 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0114726 |
| SYNJ2 | synaptojanin 2 | 0.0114683 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0113982 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0112338 |
| RELL1 | RELT-like 1 | 0.0112118 |
| NABP1 | nucleic acid binding protein 1 | 0.0111163 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.0111085 |
| LMO7 | LIM domain 7 | 0.0110247 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0107446 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0106562 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0105374 |
| FGA | fibrinogen alpha chain | 0.0104739 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0103881 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0103849 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0103632 |
| IFFO2 | intermediate filament family orphan 2 | 0.0103221 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0103209 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0102438 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0101479 |
| RPS3A | ribosomal protein S3A | 0.0101461 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.010043 |
| MYO1E | myosin IE | 0.0100416 |
| ALS2 | amyotrophic lateral sclerosis 2 (juvenile) | 0.010036 |
| ORM1 | orosomucoid 1 | 0.010006 |
| PCM1 | pericentriolar material 1 | 0.00995527 |
| WASL | Wiskott-Aldrich syndrome-like | 0.00980753 |
| XPC | xeroderma pigmentosum, complementation group C | 0.00975911 |
| TPM1 | tropomyosin 1 (alpha) | 0.00974347 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.00972516 |
| CDK13 | cyclin-dependent kinase 13 | 0.00968489 |
| PHF14 | PHD finger protein 14 | 0.00966339 |
| ZBTB44 | zinc finger and BTB domain containing 44 | 0.00954303 |
| CUL3 | cullin 3 | 0.0095273 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.00950586 |
| RBBP6 | retinoblastoma binding protein 6 | 0.00946271 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.00946164 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase | 0.00944119 |
| TBX3 | T-box 3 | 0.00940964 |
| YLPM1 | YLP motif containing 1 | 0.00939324 |
| MORF4L1 | mortality factor 4 like 1 | 0.00934569 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00933801 |
| IL4R | interleukin 4 receptor | 0.00929125 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.00927155 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.00926069 |
| AHNAK | AHNAK nucleoprotein | 0.00922561 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.00922321 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.00921308 |
| MCL1 | myeloid cell leukemia 1 | 0.00921048 |
| SKI | SKI proto-oncogene | 0.00916234 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00912927 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | 0.0091209 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.423188 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.190541 |
| FNDC3B | fibronectin type III domain containing 3B | -0.154731 |
| MT2A | metallothionein 2A | -0.115785 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114649 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0934261 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0882536 |
| NDRG1 | N-myc downstream regulated 1 | -0.0833927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.082153 |
| C3 | complement component 3 | -0.0762136 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0752387 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0697521 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0665325 |
| APOA2 | apolipoprotein A-II | -0.0664458 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0655661 |
| FTL | ferritin, light polypeptide | -0.062879 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0626997 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0622631 |
| ENO1 | enolase 1, (alpha) | -0.060377 |
| PLIN2 | perilipin 2 | -0.0599531 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0594907 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0591618 |
| RPS6 | ribosomal protein S6 | -0.0568973 |
| AHSG | alpha-2-HS-glycoprotein | -0.0561327 |
| HMGA1 | high mobility group AT-hook 1 | -0.0552882 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0539914 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0530063 |
| WDR45B | WD repeat domain 45B | -0.0514531 |
| DTNA | dystrobrevin, alpha | -0.050108 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0491985 |
| EHBP1 | EH domain binding protein 1 | -0.0484303 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.048174 |
| PARD3 | par-3 family cell polarity regulator | -0.0481481 |
| FMNL2 | formin-like 2 | -0.0481322 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0470996 |
| RPLP0 | ribosomal protein, large, P0 | -0.0458988 |
| GOLGA4 | golgin A4 | -0.0450597 |
| INSIG2 | insulin induced gene 2 | -0.0446878 |
| PEG3 | paternally expressed 3 | -0.0443144 |
| GNAS | GNAS complex locus | -0.0436222 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0425983 |
| ASPH | aspartate beta-hydroxylase | -0.0423332 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0419509 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0414335 |
| TMSB10 | thymosin beta 10 | -0.0405002 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0399779 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0393076 |
| HELZ | helicase with zinc finger | -0.0389446 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0383935 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0382082 |
| RPS24 | ribosomal protein S24 | -0.0376708 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0373557 |
| RPL35A | ribosomal protein L35a | -0.0372691 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0368683 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0366691 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0360599 |
| RPL11 | ribosomal protein L11 | -0.0357311 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0353067 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0347706 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0338797 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0336367 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0335417 |
| ATXN1 | ataxin 1 | -0.0331357 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0326667 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0325326 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0314261 |
| RPLP1 | ribosomal protein, large, P1 | -0.0312398 |
| LDHA | lactate dehydrogenase A | -0.0309853 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.030933 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0309244 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.03085 |
| FBXO42 | F-box protein 42 | -0.0307289 |
| RACK1 | receptor for activated C kinase 1 | -0.0306704 |
| RPS8 | ribosomal protein S8 | -0.0305574 |
| PKM | pyruvate kinase, muscle | -0.0303825 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0302155 |
| RPLP2 | ribosomal protein, large, P2 | -0.0300056 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.029833 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0298051 |
| MSI2 | musashi RNA-binding protein 2 | -0.0297337 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0296938 |
| RPL28 | ribosomal protein L28 | -0.0296266 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0295782 |
| ZNF292 | zinc finger protein 292 | -0.0295322 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0295065 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.028785 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0286067 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0282981 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0281191 |
| NGLY1 | N-glycanase 1 | -0.0273604 |
| RPL31 | ribosomal protein L31 | -0.0273214 |
| ATP10A | ATPase, class V, type 10A | -0.0273104 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0269821 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0269326 |
| RPS14 | ribosomal protein S14 | -0.0265998 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0265841 |
| RPL26 | ribosomal protein L26 | -0.0263802 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0262586 |
| FAM13A | family with sequence similarity 13, member A | -0.0262133 |
| RPL34 | ribosomal protein L34 | -0.0261249 |
