| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.0775432 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0533627 |
| EREG | epiregulin | 0.0462447 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0445793 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0363679 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0349134 |
| NUP58 | nucleoporin 58 | 0.0338249 |
| NDRG1 | N-myc downstream regulated 1 | 0.032337 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0303254 |
| FAM13A | family with sequence similarity 13, member A | 0.0301466 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0301044 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0300436 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0299963 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0291576 |
| KIF5B | kinesin family member 5B | 0.0287289 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0268365 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0266187 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0264285 |
| APP | amyloid beta (A4) precursor protein | 0.0261001 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0255581 |
| RPS4X | ribosomal protein S4, X-linked | 0.0251896 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0243341 |
| SERINC1 | serine incorporator 1 | 0.0240456 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0232428 |
| RPS2 | ribosomal protein S2 | 0.0231716 |
| TMSB4X | thymosin beta 4, X-linked | 0.0230802 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0226059 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0224569 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.021896 |
| DNM2 | dynamin 2 | 0.0215666 |
| RPS3 | ribosomal protein S3 | 0.0214363 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0212872 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0211103 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0206326 |
| PUM2 | pumilio RNA-binding family member 2 | 0.020577 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0203318 |
| ZNF292 | zinc finger protein 292 | 0.0202731 |
| MINK1 | misshapen-like kinase 1 | 0.0201989 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0201454 |
| AREG | amphiregulin | 0.0200907 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0200801 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0200326 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0197461 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0194069 |
| RLF | rearranged L-myc fusion | 0.01926 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0190156 |
| YME1L1 | YME1-like 1 ATPase | 0.019004 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0189995 |
| WDR45B | WD repeat domain 45B | 0.0189439 |
| SPAG9 | sperm associated antigen 9 | 0.0188894 |
| ITGB4 | integrin, beta 4 | 0.0186231 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0184469 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0184088 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0183569 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0182173 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0182006 |
| CALR | calreticulin | 0.0180415 |
| PAPOLA | poly(A) polymerase alpha | 0.0178635 |
| ANLN | anillin, actin binding protein | 0.0176787 |
| TOB1 | transducer of ERBB2, 1 | 0.0176222 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0172926 |
| MORF4L2 | mortality factor 4 like 2 | 0.0171458 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0168417 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0165186 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0162229 |
| RPS12 | ribosomal protein S12 | 0.0161814 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 | 0.016158 |
| SESN2 | sestrin 2 | 0.0158977 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.015814 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0157219 |
| FDXR | ferredoxin reductase | 0.0156705 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0156298 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0155534 |
| LRRC1 | leucine rich repeat containing 1 | 0.0155377 |
| CCNY | cyclin Y | 0.0154715 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0154403 |
| RBM39 | RNA binding motif protein 39 | 0.0154396 |
| NCKAP1 | NCK-associated protein 1 | 0.014972 |
| AFDN | afadin, adherens junction formation factor | 0.0147997 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0147386 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0147143 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0145658 |
| CCDC186 | coiled-coil domain containing 186 | 0.0144072 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0143738 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0143507 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0143206 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0143073 |
| FBXO42 | F-box protein 42 | 0.0140743 |
| PAIP2 | poly(A) binding protein interacting protein 2 | 0.0140001 |
| RSRP1 | arginine/serine-rich protein 1 | 0.0138313 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0137621 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0137484 |
| EFNA1 | ephrin-A1 | 0.0137179 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0136223 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.013577 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0135729 |
| RPS3A | ribosomal protein S3A | 0.0135094 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0134537 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | 0.0134494 |
| TLK2 | tousled-like kinase 2 | 0.0133467 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.264775 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.178975 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.15768 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.132923 |
| FAT1 | FAT atypical cadherin 1 | -0.123121 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.117271 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.10891 |
| PTMA | prothymosin, alpha | -0.10863 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.104497 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.10409 |
| ITGA6 | integrin, alpha 6 | -0.0883257 |
| TMSB10 | thymosin beta 10 | -0.084016 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0830838 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0822615 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0796424 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.078573 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0746383 |
| RPL35A | ribosomal protein L35a | -0.0686725 |
| RPS6 | ribosomal protein S6 | -0.0682476 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0664194 |
| CADPS | Ca++-dependent secretion activator | -0.0650538 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0650202 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.064744 |
| ACTG1 | actin gamma 1 | -0.0637618 |
| POTEF | POTE ankyrin domain family, member F | -0.0612152 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0592124 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0591216 |
| RPLP0 | ribosomal protein, large, P0 | -0.0586016 |
| LMO7 | LIM domain 7 | -0.0579092 |
| ASPH | aspartate beta-hydroxylase | -0.0570306 |
| ANXA2 | annexin A2 | -0.0568902 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0565294 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0565198 |
| H1-0 | H1.0 linker histone | -0.0530914 |
| S100A6 | S100 calcium binding protein A6 | -0.0530003 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0509326 |
| NPSR1 | neuropeptide S receptor 1 | -0.0508147 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.050027 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0498552 |
| TRIM2 | tripartite motif containing 2 | -0.0498075 |
| TNS4 | tensin 4 | -0.0497183 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0481417 |
| HMGA1 | high mobility group AT-hook 1 | -0.0481374 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.047867 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0474961 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0465847 |
| FHIT | fragile histidine triad | -0.044723 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0446101 |
| MED13 | mediator complex subunit 13 | -0.0424707 |
| PERP | PERP, TP53 apoptosis effector | -0.0424435 |
| GPHN | gephyrin | -0.0424177 |
| PIGR | polymeric immunoglobulin receptor | -0.0421886 |
| AHNAK | AHNAK nucleoprotein | -0.041853 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0408448 |
| CD44 | CD44 molecule (Indian blood group) | -0.0402008 |
| NRXN3 | neurexin 3 | -0.0400916 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0392539 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0389921 |
| ATXN1 | ataxin 1 | -0.0389487 |
| PARD3B | par-3 family cell polarity regulator beta | -0.038604 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0384682 |
| ACTN4 | actinin, alpha 4 | -0.0379779 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0376855 |
| KRT8 | keratin 8, type II | -0.0370849 |
| PTEN | phosphatase and tensin homolog | -0.0365061 |
| RAB10 | RAB10, member RAS oncogene family | -0.0362503 |
| AGR2 | anterior gradient 2 | -0.0361153 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0359149 |
| POF1B | premature ovarian failure, 1B | -0.0357557 |
| SH3D19 | SH3 domain containing 19 | -0.035711 |
| EHBP1 | EH domain binding protein 1 | -0.0356592 |
| MUC13 | mucin 13, cell surface associated | -0.035658 |
| PARD3 | par-3 family cell polarity regulator | -0.0349241 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0346804 |
| GOLGB1 | golgin B1 | -0.0344829 |
| CCND1 | cyclin D1 | -0.0344662 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0342386 |
| PFN1 | profilin 1 | -0.034188 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0337266 |
| MYO1E | myosin IE | -0.0336743 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0334896 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0330057 |
| RPL19 | ribosomal protein L19 | -0.0329762 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | -0.0327872 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0321162 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0320237 |
| NEBL | nebulette | -0.0317618 |
| NFIA | nuclear factor I/A | -0.0317473 |
| PKM | pyruvate kinase, muscle | -0.0315237 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0315101 |
| RPLP1 | ribosomal protein, large, P1 | -0.030962 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0309276 |
| MUC17 | mucin 17, cell surface associated | -0.0308715 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0307727 |
| CALB1 | calbindin 1, 28kDa | -0.0307279 |
| CDK6 | cyclin-dependent kinase 6 | -0.0306666 |
| FTL | ferritin, light polypeptide | -0.0304411 |
| SMYD3 | SET and MYND domain containing 3 | -0.0303957 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0298794 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0298641 |
