| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.129838 |
| TXNRD1 | thioredoxin reductase 1 | 0.101752 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0815343 |
| CENPF | centromere protein F, 350/400kDa | 0.0665917 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0591499 |
| MKI67 | marker of proliferation Ki-67 | 0.0545495 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0539954 |
| TOP1 | topoisomerase (DNA) I | 0.0489406 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.045055 |
| RTN4 | reticulon 4 | 0.0381996 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0377301 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0372453 |
| POTEF | POTE ankyrin domain family, member F | 0.0351087 |
| MT1E | metallothionein 1E | 0.0342208 |
| EZR | ezrin | 0.0311186 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0299807 |
| MT1X | metallothionein 1X | 0.0297021 |
| FKBP5 | FK506 binding protein 5 | 0.0291839 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0287948 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0286949 |
| YBX1 | Y box binding protein 1 | 0.0284575 |
| RAI1 | retinoic acid induced 1 | 0.0278481 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0276068 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0266992 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0257096 |
| SET | SET nuclear proto-oncogene | 0.0243878 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0241175 |
| TPX2 | TPX2, microtubule-associated | 0.0239885 |
| BCL2L1 | BCL2-like 1 | 0.0236192 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0234542 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0234067 |
| EMP1 | epithelial membrane protein 1 | 0.0227953 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0227315 |
| TMEM41B | transmembrane protein 41B | 0.0222374 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0220259 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0217979 |
| RPS4X | ribosomal protein S4, X-linked | 0.021095 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0209975 |
| CENPE | centromere protein E, 312kDa | 0.0206151 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0205798 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0203189 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0202229 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.0200701 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0200279 |
| PCBP2 | poly(rC) binding protein 2 | 0.019577 |
| KIF14 | kinesin family member 14 | 0.0194158 |
| EGR1 | early growth response 1 | 0.0193432 |
| PYGB | phosphorylase, glycogen; brain | 0.0191896 |
| KLF6 | Kruppel-like factor 6 | 0.0190715 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0189953 |
| WDR43 | WD repeat domain 43 | 0.0188937 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0188251 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0185438 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.018347 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0182337 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0181745 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.018112 |
| MSN | moesin | 0.0180903 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0175946 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0175795 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0173175 |
| CCDC88A | coiled-coil domain containing 88A | 0.0168517 |
| NUP58 | nucleoporin 58 | 0.0164332 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0161784 |
| PCM1 | pericentriolar material 1 | 0.0161043 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0159676 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0159656 |
| ANGPTL4 | angiopoietin-like 4 | 0.0159652 |
| MATR3 | matrin 3 | 0.0159223 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0158423 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0157905 |
| ANLN | anillin, actin binding protein | 0.0154311 |
| ECT2 | epithelial cell transforming 2 | 0.0152829 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0151551 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0151177 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0150519 |
| ITGB4 | integrin, beta 4 | 0.0150496 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0149099 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0149098 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0148096 |
| RPL5 | ribosomal protein L5 | 0.0147505 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0144992 |
| CBX3 | chromobox homolog 3 | 0.0144042 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0143909 |
| CDCA2 | cell division cycle associated 2 | 0.0141845 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0141755 |
| KIF18B | kinesin family member 18B | 0.0140245 |
| PNN | pinin, desmosome associated protein | 0.013915 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0138047 |
| CEP170 | centrosomal protein 170kDa | 0.0137915 |
| IL6ST | interleukin 6 signal transducer | 0.0137306 |
| CLTC | clathrin, heavy chain (Hc) | 0.0136595 |
| GAS2L3 | growth arrest-specific 2 like 3 | 0.0135923 |
| TPM3 | tropomyosin 3 | 0.0133552 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0132511 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0132005 |
| ERCC1 | excision repair cross-complementation group 1 | 0.0131843 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0128115 |
| MTF2 | metal response element binding transcription factor 2 | 0.0127698 |
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.0127684 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.223771 |
| TP63 | tumor protein p63 | -0.220701 |
| CD44 | CD44 molecule (Indian blood group) | -0.176744 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.153577 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.150559 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.140759 |
| DST | dystonin | -0.13437 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.125698 |
| CADM2 | cell adhesion molecule 2 | -0.123718 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117294 |
| HLA-B | major histocompatibility complex, class I, B | -0.114711 |
| FMNL2 | formin-like 2 | -0.103664 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.100496 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0937411 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0863054 |
| EHBP1 | EH domain binding protein 1 | -0.0818623 |
| PDE10A | phosphodiesterase 10A | -0.0809643 |
| EPHA4 | EPH receptor A4 | -0.0770312 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0755144 |
| TNS3 | tensin 3 | -0.0728109 |
| EFNA5 | ephrin-A5 | -0.0713612 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0705748 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0705248 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0700724 |
| SP100 | SP100 nuclear antigen | -0.0683034 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0682737 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0672922 |
| TMSB10 | thymosin beta 10 | -0.0670531 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0667599 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0651441 |
| RIGI | RNA sensor RIG-I | -0.0617454 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0589382 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0580665 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0558801 |
| RNF213 | ring finger protein 213 | -0.0555169 |
| TMSB4X | thymosin beta 4, X-linked | -0.055514 |
| HDAC9 | histone deacetylase 9 | -0.0541765 |
| CMIP | c-Maf inducing protein | -0.0506527 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0498242 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0496718 |
| LRRC49 | leucine rich repeat containing 49 | -0.0494438 |
| PRELID2 | PRELI domain containing 2 | -0.0486322 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0484825 |
| PLSCR1 | phospholipid scramblase 1 | -0.048202 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0479155 |
| PTK2 | protein tyrosine kinase 2 | -0.0469609 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0456933 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0449527 |
| DENND1A | DENN/MADD domain containing 1A | -0.0435215 |
| RAD51B | RAD51 paralog B | -0.0434457 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0426238 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0414677 |
| VCL | vinculin | -0.0413975 |
| PTMA | prothymosin, alpha | -0.0412388 |
| SQSTM1 | sequestosome 1 | -0.0412021 |
| MYOF | myoferlin | -0.0408383 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0404173 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0403308 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0390776 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0388762 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.038753 |
| AEBP2 | AE binding protein 2 | -0.0385325 |
| DPH6 | diphthamine biosynthesis 6 | -0.0381217 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0379623 |
| NEK10 | NIMA-related kinase 10 | -0.0378048 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0375171 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0373786 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0363858 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0363471 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0355186 |
| RPL35A | ribosomal protein L35a | -0.035146 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0350696 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0344777 |
| EXOC4 | exocyst complex component 4 | -0.0343349 |
| TGM2 | transglutaminase 2 | -0.0341196 |
| DNER | delta/notch-like EGF repeat containing | -0.0339504 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.033873 |
| INTS6 | integrator complex subunit 6 | -0.0338438 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0337628 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0330586 |
| ECE1 | endothelin converting enzyme 1 | -0.0330276 |
| RAB27B | RAB27B, member RAS oncogene family | -0.032701 |
| ZNF217 | zinc finger protein 217 | -0.0322111 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0320657 |
| NDRG1 | N-myc downstream regulated 1 | -0.0319952 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0317324 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0315591 |
| STK17A | serine/threonine kinase 17a | -0.0313704 |
| APP | amyloid beta (A4) precursor protein | -0.0309558 |
| CAPRIN2 | caprin family member 2 | -0.0309208 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0309198 |
| RPL26 | ribosomal protein L26 | -0.0307799 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.030451 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0303281 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0300167 |
| SMAD3 | SMAD family member 3 | -0.0299122 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0296262 |
| WDR27 | WD repeat domain 27 | -0.0294083 |
| LOXL2 | lysyl oxidase-like 2 | -0.0286929 |
| COL5A2 | collagen, type V, alpha 2 | -0.0282055 |
