| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Econazole_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.118436 |
| NDRG1 | N-myc downstream regulated 1 | 0.106838 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0649999 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0619088 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0564214 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0554517 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553296 |
| LAMC2 | laminin, gamma 2 | 0.0518176 |
| FAM13A | family with sequence similarity 13, member A | 0.0492281 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0477218 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0452227 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0451744 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0445234 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0410269 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0406517 |
| MCL1 | myeloid cell leukemia 1 | 0.0385753 |
| STC1 | stanniocalcin 1 | 0.0355786 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0335027 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0329407 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0315501 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0313757 |
| OSMR | oncostatin M receptor | 0.0298246 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0295484 |
| NGLY1 | N-glycanase 1 | 0.0293639 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0284879 |
| CDCP1 | CUB domain containing protein 1 | 0.0284478 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0282519 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0277612 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0272701 |
| MSN | moesin | 0.0271866 |
| ARRDC3 | arrestin domain containing 3 | 0.0269005 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0266548 |
| EGR1 | early growth response 1 | 0.0261098 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0260728 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.025471 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0252122 |
| PDE8A | phosphodiesterase 8A | 0.0251489 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0247225 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.024142 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.023286 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0230581 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0230512 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0223362 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.021764 |
| KRT18 | keratin 18, type I | 0.0214795 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0213283 |
| SCEL | sciellin | 0.0207162 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0202637 |
| RCOR1 | REST corepressor 1 | 0.020183 |
| AREG | amphiregulin | 0.019189 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0191837 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0191813 |
| ATP13A3 | ATPase type 13A3 | 0.0191549 |
| VCL | vinculin | 0.0190953 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0187083 |
| CCNL1 | cyclin L1 | 0.0187018 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0183832 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0182375 |
| PCBP2 | poly(rC) binding protein 2 | 0.0180849 |
| CPE | carboxypeptidase E | 0.0179215 |
| VEGFC | vascular endothelial growth factor C | 0.0177075 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0176054 |
| TPM4 | tropomyosin 4 | 0.01752 |
| SNX9 | sorting nexin 9 | 0.0174741 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0173539 |
| POTEF | POTE ankyrin domain family, member F | 0.0172216 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0171332 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0170638 |
| CSNK1E | casein kinase 1, epsilon | 0.0170561 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0169537 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0169147 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0168931 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0168256 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0167328 |
| MYO1E | myosin IE | 0.0167301 |
| SEPTIN10 | septin 10 | 0.0163996 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.016292 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0162821 |
| RNF149 | ring finger protein 149 | 0.0162746 |
| AMOTL1 | angiomotin like 1 | 0.0162076 |
| KMT5B | lysine methyltransferase 5B | 0.0162012 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0161285 |
| TPM3 | tropomyosin 3 | 0.0156426 |
| SETD5 | SET domain containing 5 | 0.0156248 |
| SMTN | smoothelin | 0.0150171 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0148059 |
| ASPH | aspartate beta-hydroxylase | 0.0146744 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0145527 |
| ACTN1 | actinin, alpha 1 | 0.0143594 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0141559 |
| SDC1 | syndecan 1 | 0.0140148 |
| SMAD4 | SMAD family member 4 | 0.0139572 |
| NUP58 | nucleoporin 58 | 0.0138447 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0137095 |
| DUSP5 | dual specificity phosphatase 5 | 0.0133674 |
| PLAUR | plasminogen activator, urokinase receptor | 0.013315 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.013258 |
| TMEM45B | transmembrane protein 45B | 0.013251 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0131031 |
| SPAG9 | sperm associated antigen 9 | 0.0130815 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.11587 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.106485 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0950432 |
| TMSB10 | thymosin beta 10 | -0.081562 |
| H1-0 | H1.0 linker histone | -0.080057 |
| TXNRD1 | thioredoxin reductase 1 | -0.08005 |
| RPLP1 | ribosomal protein, large, P1 | -0.068903 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0613909 |
| HDLBP | high density lipoprotein binding protein | -0.0569159 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.056718 |
| PTMA | prothymosin, alpha | -0.0566655 |
| RPL35A | ribosomal protein L35a | -0.0556144 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0539104 |
| LAMB3 | laminin, beta 3 | -0.0531449 |
| MT2A | metallothionein 2A | -0.0523447 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0519587 |
| CANX | calnexin | -0.0479386 |
| RPS24 | ribosomal protein S24 | -0.0470713 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0469498 |
| S100P | S100 calcium binding protein P | -0.0467382 |
| FTL | ferritin, light polypeptide | -0.0462729 |
| RPLP0 | ribosomal protein, large, P0 | -0.044612 |
| AHNAK | AHNAK nucleoprotein | -0.0442067 |
| RPS8 | ribosomal protein S8 | -0.0432521 |
| RPL34 | ribosomal protein L34 | -0.0431703 |
| ANXA2 | annexin A2 | -0.0429952 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0414389 |
| HBP1 | HMG-box transcription factor 1 | -0.0410581 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0408534 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.038519 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0382091 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0381356 |
| INTS6 | integrator complex subunit 6 | -0.0377136 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.036856 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0366861 |
| OGA | O-GlcNAcase | -0.0366431 |
| EMP1 | epithelial membrane protein 1 | -0.0360368 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0350287 |
| RPL4 | ribosomal protein L4 | -0.0346625 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0346329 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0345193 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0341091 |
| ABLIM1 | actin binding LIM protein 1 | -0.0340893 |
| RPS3 | ribosomal protein S3 | -0.0339926 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.033745 |
| PGK1 | phosphoglycerate kinase 1 | -0.033179 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0330058 |
| UVRAG | UV radiation resistance associated | -0.0328791 |
| TKT | transketolase | -0.0320163 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0318587 |
| RPS25 | ribosomal protein S25 | -0.0314278 |
| B2M | beta-2-microglobulin | -0.0313334 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0312117 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | -0.0310035 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0302795 |
| GM2A | GM2 ganglioside activator | -0.0300901 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0292562 |
| RPL31 | ribosomal protein L31 | -0.0292555 |
| RPS27A | ribosomal protein S27a | -0.0289369 |
| GOLGB1 | golgin B1 | -0.0288052 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0282916 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0280586 |
| ARF1 | ADP-ribosylation factor 1 | -0.0277557 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0271549 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0269765 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0268984 |
| RPL11 | ribosomal protein L11 | -0.0264439 |
| RPL19 | ribosomal protein L19 | -0.0262555 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.0261952 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0261945 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0261387 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0260232 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0257987 |
| RBM39 | RNA binding motif protein 39 | -0.0256091 |
| DENND4A | DENN/MADD domain containing 4A | -0.0254627 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.025331 |
| RPL7 | ribosomal protein L7 | -0.0253301 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0252588 |
| SEC61G | Sec61 gamma subunit | -0.0251299 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0247486 |
| RPL30 | ribosomal protein L30 | -0.0246628 |
| RPL8 | ribosomal protein L8 | -0.0246031 |
| RPS23 | ribosomal protein S23 | -0.0243026 |
| RPL37A | ribosomal protein L37a | -0.0242967 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0242907 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0242469 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0241689 |
| RACK1 | receptor for activated C kinase 1 | -0.0240657 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0239713 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0234983 |
| CEP350 | centrosomal protein 350kDa | -0.0233835 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0233537 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.022989 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0227693 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0226526 |
| RNF169 | ring finger protein 169 | -0.0225595 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0224304 |
| SQSTM1 | sequestosome 1 | -0.0221283 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0218454 |
| RPL26 | ribosomal protein L26 | -0.0218428 |
