| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0991897 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0545258 |
| MORF4L2 | mortality factor 4 like 2 | 0.045575 |
| KRT18 | keratin 18, type I | 0.0381523 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355579 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0347734 |
| COPA | coatomer protein complex, subunit alpha | 0.0331298 |
| RPS4X | ribosomal protein S4, X-linked | 0.0320937 |
| NUP58 | nucleoporin 58 | 0.0282586 |
| SET | SET nuclear proto-oncogene | 0.0249532 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0246369 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0237666 |
| HELZ | helicase with zinc finger | 0.0228269 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0227787 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0215006 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0205358 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0200707 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0200567 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0197071 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0196081 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0195949 |
| ACTN1 | actinin, alpha 1 | 0.0195563 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0194814 |
| PAPOLA | poly(A) polymerase alpha | 0.0191592 |
| MINK1 | misshapen-like kinase 1 | 0.0190622 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0189864 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0185508 |
| ARRDC3 | arrestin domain containing 3 | 0.0183363 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0182295 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0181905 |
| TMEM165 | transmembrane protein 165 | 0.0181029 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0175445 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0175058 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.017407 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0173612 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0173227 |
| IGF2 | insulin-like growth factor 2 | 0.0172678 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0167191 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0166066 |
| CANX | calnexin | 0.0162547 |
| RPS2 | ribosomal protein S2 | 0.0157964 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0154707 |
| TFG | TRK-fused gene | 0.0153672 |
| TPM3 | tropomyosin 3 | 0.0151695 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0151355 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0150267 |
| PRELID2 | PRELI domain containing 2 | 0.0149462 |
| TNPO3 | transportin 3 | 0.0148868 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0148769 |
| PREPL | prolyl endopeptidase-like | 0.0147386 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0146048 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0144899 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0143837 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0143133 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0141128 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0140151 |
| ZNF292 | zinc finger protein 292 | 0.0138902 |
| NONO | non-POU domain containing, octamer-binding | 0.013749 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0136872 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0136597 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0136056 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | 0.0135736 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.013545 |
| KMT5B | lysine methyltransferase 5B | 0.0134799 |
| LDHA | lactate dehydrogenase A | 0.0132742 |
| PHF21A | PHD finger protein 21A | 0.0132312 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0131777 |
| SRP54 | signal recognition particle 54kDa | 0.0130935 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0129461 |
| SFTPA2 | surfactant protein A2 | 0.012689 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0126165 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0126139 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0124726 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0124165 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0124081 |
| CALU | calumenin | 0.0122687 |
| GOLGA4 | golgin A4 | 0.012263 |
| YBX1 | Y box binding protein 1 | 0.0122018 |
| PNN | pinin, desmosome associated protein | 0.0121543 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0120992 |
| NOP58 | NOP58 ribonucleoprotein | 0.0120372 |
| UBQLN1 | ubiquilin 1 | 0.011997 |
| WDR45B | WD repeat domain 45B | 0.0119367 |
| PCBP2 | poly(rC) binding protein 2 | 0.0118304 |
| TMEM39A | transmembrane protein 39A | 0.0117968 |
| CEP192 | centrosomal protein 192kDa | 0.0117892 |
| SEC24A | SEC24 family member A | 0.0117887 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0115487 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | 0.0115271 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0114295 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.011419 |
| SNX14 | sorting nexin 14 | 0.0113471 |
| NDRG1 | N-myc downstream regulated 1 | 0.0113443 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0113442 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0113028 |
| NOTCH2 | notch 2 | 0.0113028 |
| TMEM14B | transmembrane protein 14B | 0.0112355 |
| CLTC | clathrin, heavy chain (Hc) | 0.0111299 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.011081 |
| APP | amyloid beta (A4) precursor protein | 0.0109864 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.168394 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.135077 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.124676 |
| TMSB10 | thymosin beta 10 | -0.108481 |
| GRAMD1B | GRAM domain containing 1B | -0.0834401 |
| YBX3 | Y box binding protein 3 | -0.0736233 |
| TXNRD1 | thioredoxin reductase 1 | -0.0711839 |
| VIM | vimentin | -0.0624743 |
| OSMR | oncostatin M receptor | -0.0573058 |
| ACTG1 | actin gamma 1 | -0.0496371 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.048084 |
| IGF1R | insulin-like growth factor 1 receptor | -0.04784 |
| RPL35A | ribosomal protein L35a | -0.0459101 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0439686 |
| PTMA | prothymosin, alpha | -0.0429607 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0422814 |
| RPS21 | ribosomal protein S21 | -0.0413775 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0402313 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0401651 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0396863 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0396532 |
| RPLP1 | ribosomal protein, large, P1 | -0.0395264 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0394857 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0375308 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0372437 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0370372 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0362156 |
| CDK17 | cyclin-dependent kinase 17 | -0.0338848 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0337575 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0333577 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0329014 |
| RPLP0 | ribosomal protein, large, P0 | -0.0327948 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0327145 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0322114 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0320956 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0312476 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0311522 |
| EXOC4 | exocyst complex component 4 | -0.0309264 |
| RPL19 | ribosomal protein L19 | -0.0308245 |
| EGR1 | early growth response 1 | -0.030706 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0306278 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0304499 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0298537 |
| RPL12 | ribosomal protein L12 | -0.0290285 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0290059 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0287537 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0285478 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.028384 |
| HLA-B | major histocompatibility complex, class I, B | -0.027312 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0269954 |
| RPL34 | ribosomal protein L34 | -0.0266844 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0266651 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0264941 |
| AHNAK | AHNAK nucleoprotein | -0.0264826 |
| PLSCR1 | phospholipid scramblase 1 | -0.0262247 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0260111 |
| CAVIN1 | caveolae associated protein 1 | -0.0258292 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0256047 |
| RPL9 | ribosomal protein L9 | -0.0252829 |
| RPLP2 | ribosomal protein, large, P2 | -0.0252567 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0252125 |
| TPI1 | triosephosphate isomerase 1 | -0.0251628 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0251274 |
| ATP11A | ATPase, class VI, type 11A | -0.0250729 |
| PTK2 | protein tyrosine kinase 2 | -0.0249234 |
| CCND1 | cyclin D1 | -0.0246455 |
| PRRC2B | proline-rich coiled-coil 2B | -0.024244 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0238968 |
| RPS19 | ribosomal protein S19 | -0.0234106 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0233146 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0232857 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0232529 |
| PFN1 | profilin 1 | -0.0232184 |
| H1-0 | H1.0 linker histone | -0.0230334 |
| RPL38 | ribosomal protein L38 | -0.0228084 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.022799 |
| IER3 | immediate early response 3 | -0.022418 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.022363 |
| HMGA2 | high mobility group AT-hook 2 | -0.022281 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0222749 |
| PDE10A | phosphodiesterase 10A | -0.0221306 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0220922 |
| S100A11 | S100 calcium binding protein A11 | -0.0217852 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0217666 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0217626 |
| POTEF | POTE ankyrin domain family, member F | -0.0217323 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0217322 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0215468 |
| LDHB | lactate dehydrogenase B | -0.0215129 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0212283 |
| S100A6 | S100 calcium binding protein A6 | -0.020888 |
| PMP22 | peripheral myelin protein 22 | -0.0208702 |
| RTN4 | reticulon 4 | -0.0206277 |
| YAP1 | Yes-associated protein 1 | -0.0201595 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0200611 |
| SMAD3 | SMAD family member 3 | -0.0199798 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0198825 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0197436 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0196218 |
| RIGI | RNA sensor RIG-I | -0.0195963 |
