| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Econazole_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.064388 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0541223 |
| RACK1 | receptor for activated C kinase 1 | 0.0531197 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0487453 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0473479 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0464627 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0386756 |
| YBX1 | Y box binding protein 1 | 0.0370213 |
| RPS4X | ribosomal protein S4, X-linked | 0.0356768 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0352667 |
| RPS8 | ribosomal protein S8 | 0.0348048 |
| RPS3 | ribosomal protein S3 | 0.034661 |
| RPL23 | ribosomal protein L23 | 0.0330049 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0329125 |
| CALR | calreticulin | 0.0324442 |
| SET | SET nuclear proto-oncogene | 0.0300536 |
| KRT18 | keratin 18, type I | 0.0299412 |
| RPLP1 | ribosomal protein, large, P1 | 0.0282318 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0276252 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0274291 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0273788 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.025334 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0245778 |
| RPS12 | ribosomal protein S12 | 0.0245436 |
| G0S2 | G0/G1 switch 2 | 0.0241321 |
| RPS19 | ribosomal protein S19 | 0.0229868 |
| RPS17 | ribosomal protein S17 | 0.0228108 |
| MKI67 | marker of proliferation Ki-67 | 0.0221782 |
| FTL | ferritin, light polypeptide | 0.0213097 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0208559 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0207478 |
| RPS2 | ribosomal protein S2 | 0.0205582 |
| RPL12 | ribosomal protein L12 | 0.0205154 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0202974 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0198178 |
| S100A10 | S100 calcium binding protein A10 | 0.0194638 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0192701 |
| DSPP | dentin sialophosphoprotein | 0.0192369 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0189193 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.0185381 |
| RPL5 | ribosomal protein L5 | 0.0185096 |
| PEG10 | paternally expressed 10 | 0.0183881 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0182467 |
| RPS29 | ribosomal protein S29 | 0.0182416 |
| RPL37A | ribosomal protein L37a | 0.0178569 |
| RPL8 | ribosomal protein L8 | 0.0174587 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0172343 |
| STEAP4 | STEAP family member 4 | 0.016807 |
| RPL37 | ribosomal protein L37 | 0.0167758 |
| HMGB2 | high mobility group box 2 | 0.016522 |
| RPL11 | ribosomal protein L11 | 0.0162576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0161877 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0159552 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0158676 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.015673 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0155426 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0155397 |
| RPS27 | ribosomal protein S27 | 0.0152627 |
| ANXA1 | annexin A1 | 0.0152325 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0149612 |
| RPLP2 | ribosomal protein, large, P2 | 0.0148842 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0148376 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0148009 |
| LAMC2 | laminin, gamma 2 | 0.0147663 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0146656 |
| ARRDC3 | arrestin domain containing 3 | 0.014638 |
| KLF6 | Kruppel-like factor 6 | 0.0146197 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0144538 |
| ACTN1 | actinin, alpha 1 | 0.014349 |
| ENO1 | enolase 1, (alpha) | 0.0139608 |
| CBX3 | chromobox homolog 3 | 0.0138873 |
| RPL18 | ribosomal protein L18 | 0.0138585 |
| TUBB | tubulin, beta class I | 0.0136681 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0134532 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0134321 |
| RPL36 | ribosomal protein L36 | 0.0131643 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0131157 |
| HMGB1 | high mobility group box 1 | 0.0130677 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 0.0129998 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0127835 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0124528 |
| SQSTM1 | sequestosome 1 | 0.0123585 |
| COX6C | cytochrome c oxidase subunit VIc | 0.0122572 |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.0121402 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0121364 |
| RPLP0 | ribosomal protein, large, P0 | 0.0119868 |
| RPS14 | ribosomal protein S14 | 0.0118221 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0118029 |
| RPL26 | ribosomal protein L26 | 0.011764 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0116984 |
| GPX4 | glutathione peroxidase 4 | 0.0116553 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0116203 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0116047 |
| LDHB | lactate dehydrogenase B | 0.0115891 |
| EFNA1 | ephrin-A1 | 0.0115522 |
| DEK | DEK proto-oncogene | 0.0115503 |
| RPL23A | ribosomal protein L23a | 0.0114363 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | 0.011386 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0113096 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0112371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | -0.186058 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.112965 |
| GRB10 | growth factor receptor-bound protein 10 | -0.11114 |
| TSC22D2 | TSC22 domain family, member 2 | -0.110684 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.103111 |
| MYO6 | myosin VI | -0.102201 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.102141 |
| ERBIN | erbb2 interacting protein | -0.101704 |
| POTEF | POTE ankyrin domain family, member F | -0.0990539 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0973553 |
| LMO7 | LIM domain 7 | -0.0958596 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0886012 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0870205 |
| ACTG1 | actin gamma 1 | -0.0866575 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0838647 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0819475 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0813206 |
| GOLGA4 | golgin A4 | -0.0789234 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.07767 |
| CD2AP | CD2-associated protein | -0.0773364 |
| COPA | coatomer protein complex, subunit alpha | -0.0772588 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0764524 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0752849 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0731476 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0727209 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0726136 |
| PTK2 | protein tyrosine kinase 2 | -0.0714051 |
| ASPH | aspartate beta-hydroxylase | -0.0712948 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0700348 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0695494 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0684088 |
| RCOR1 | REST corepressor 1 | -0.0682495 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0679511 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0678557 |
| FAM3C | family with sequence similarity 3, member C | -0.0677644 |
| NDRG1 | N-myc downstream regulated 1 | -0.0668388 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0652391 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0641103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0606403 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0580679 |
| SETD5 | SET domain containing 5 | -0.0572891 |
| EFNA5 | ephrin-A5 | -0.0559643 |
| DTNA | dystrobrevin, alpha | -0.0559262 |
| JMJD1C | jumonji domain containing 1C | -0.0557583 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0556138 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0551393 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0548549 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.054729 |
| FBXO32 | F-box protein 32 | -0.0542342 |
| RBM39 | RNA binding motif protein 39 | -0.0535276 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0532445 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.053187 |
| FAM13A | family with sequence similarity 13, member A | -0.0528702 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.052306 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0519464 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0515761 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0513419 |
| WASF2 | WAS protein family, member 2 | -0.0510026 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0509171 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0500242 |
| CD109 | CD109 molecule | -0.0485812 |
| PGK1 | phosphoglycerate kinase 1 | -0.0478187 |
| SLMAP | sarcolemma associated protein | -0.047629 |
| TMEM165 | transmembrane protein 165 | -0.0468735 |
| TMF1 | TATA element modulatory factor 1 | -0.04686 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0468502 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0468148 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0462897 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0460154 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0458937 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0456903 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0449736 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0447877 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0443972 |
| TMSB10 | thymosin beta 10 | -0.0438553 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.043468 |
| SPAG9 | sperm associated antigen 9 | -0.043351 |
| RNF145 | ring finger protein 145 | -0.0425946 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0423452 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0418858 |
| ZNF207 | zinc finger protein 207 | -0.0418049 |
| TMEM263 | transmembrane protein 263 | -0.0415398 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0414582 |
| BBX | bobby sox homolog (Drosophila) | -0.0414538 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0414155 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0413702 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0411682 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0411373 |
| MXD1 | MAX dimerization protein 1 | -0.0410503 |
| CTBP2 | C-terminal binding protein 2 | -0.0405388 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0404647 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0403374 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0402784 |
| RBM25 | RNA binding motif protein 25 | -0.0399847 |
| HELZ | helicase with zinc finger | -0.0396275 |
| SEC24D | SEC24 family member D | -0.0393529 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0392681 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.039152 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0390728 |
| MCU | mitochondrial calcium uniporter | -0.038955 |
