| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Econazole perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Econazole_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.11988 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.117315 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114257 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0951002 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0743841 |
| PTMA | prothymosin, alpha | 0.0603509 |
| PEG10 | paternally expressed 10 | 0.0534048 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0493975 |
| CALR | calreticulin | 0.0464676 |
| POTEF | POTE ankyrin domain family, member F | 0.0430078 |
| RPS16 | ribosomal protein S16 | 0.0428529 |
| RPS6 | ribosomal protein S6 | 0.0426622 |
| TMSB4X | thymosin beta 4, X-linked | 0.0413778 |
| TPX2 | TPX2, microtubule-associated | 0.0412602 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0408677 |
| LDHA | lactate dehydrogenase A | 0.0390194 |
| RPS2 | ribosomal protein S2 | 0.0389885 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0378295 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0370446 |
| RPS12 | ribosomal protein S12 | 0.0364932 |
| SET | SET nuclear proto-oncogene | 0.0363327 |
| TMSB10 | thymosin beta 10 | 0.0357106 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.034726 |
| PFN1 | profilin 1 | 0.0344031 |
| RPLP1 | ribosomal protein, large, P1 | 0.0343233 |
| YBX1 | Y box binding protein 1 | 0.0343195 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.034174 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0322541 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0317936 |
| RPS4X | ribosomal protein S4, X-linked | 0.0309899 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0295987 |
| CENPF | centromere protein F, 350/400kDa | 0.0291753 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0289894 |
| RAI1 | retinoic acid induced 1 | 0.0289027 |
| SNX6 | sorting nexin 6 | 0.0285722 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0285372 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0276 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0275813 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0272897 |
| FBL | fibrillarin | 0.0271089 |
| CANX | calnexin | 0.0264747 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0263204 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258855 |
| RPL12 | ribosomal protein L12 | 0.0254141 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0250963 |
| CFL2 | cofilin 2 (muscle) | 0.0246641 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0245104 |
| B2M | beta-2-microglobulin | 0.0244139 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0235466 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0234503 |
| ACTG1 | actin gamma 1 | 0.0233723 |
| RACK1 | receptor for activated C kinase 1 | 0.023246 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0231251 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0231239 |
| RPS19 | ribosomal protein S19 | 0.0230992 |
| RPL19 | ribosomal protein L19 | 0.022833 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0225952 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0225944 |
| S100A10 | S100 calcium binding protein A10 | 0.0225337 |
| RPLP0 | ribosomal protein, large, P0 | 0.0224571 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.0223896 |
| MATR3 | matrin 3 | 0.0220921 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0220567 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0218842 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0218449 |
| HMGB1 | high mobility group box 1 | 0.0218081 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0217447 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0217119 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0216197 |
| MKI67 | marker of proliferation Ki-67 | 0.021598 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0215673 |
| RPL11 | ribosomal protein L11 | 0.0215366 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0214206 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0213265 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0210062 |
| RPS8 | ribosomal protein S8 | 0.0208689 |
| NOP58 | NOP58 ribonucleoprotein | 0.0207293 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0206601 |
| RPL5 | ribosomal protein L5 | 0.0205105 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0203573 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0203502 |
| SFTPA2 | surfactant protein A2 | 0.0203235 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0200321 |
| ZFR | zinc finger RNA binding protein | 0.01995 |
| DSTN | destrin (actin depolymerizing factor) | 0.0198906 |
| FKBP5 | FK506 binding protein 5 | 0.0198585 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0198218 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.019774 |
| HMGB2 | high mobility group box 2 | 0.0196715 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0194765 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0193971 |
| TPM3 | tropomyosin 3 | 0.0193351 |
| LBR | lamin B receptor | 0.01907 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0190124 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0189574 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0188617 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0188225 |
| CCNA2 | cyclin A2 | 0.0183278 |
| RPL30 | ribosomal protein L30 | 0.0182641 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0181732 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.27902 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.209291 |
| CADM2 | cell adhesion molecule 2 | -0.191707 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.166849 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.145981 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.130038 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.120757 |
| COL5A2 | collagen, type V, alpha 2 | -0.109883 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.100686 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0957562 |
| PCDH9 | protocadherin 9 | -0.09159 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0839693 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0835274 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0800851 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0785097 |
| TENM3 | teneurin transmembrane protein 3 | -0.0784431 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0740549 |
| GPC3 | glypican 3 | -0.0737049 |
| ITGAV | integrin, alpha V | -0.0709387 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0700863 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0686117 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0672548 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0663966 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0626726 |
| HMCN1 | hemicentin 1 | -0.0606172 |
| RAD51B | RAD51 paralog B | -0.0604296 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0597812 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0596142 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0584833 |
| LRRC4C | leucine rich repeat containing 4C | -0.0580891 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0577399 |
| PRELID2 | PRELI domain containing 2 | -0.0562664 |
| MYO10 | myosin X | -0.0533106 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0516736 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0507864 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0505568 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0498381 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0487254 |
| MED13L | mediator complex subunit 13-like | -0.0478118 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0473464 |
| NEBL | nebulette | -0.0464853 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0462501 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0455916 |
| NHSL1 | NHS-like 1 | -0.0450816 |
| HDAC9 | histone deacetylase 9 | -0.0448597 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0446649 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0442799 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.043879 |
| SHROOM3 | shroom family member 3 | -0.0433854 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0424213 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0422516 |
| PHIP | pleckstrin homology domain interacting protein | -0.0418361 |
| RBM20 | RNA binding motif protein 20 | -0.0412928 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0397074 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0390133 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0385713 |
| NTM | neurotrimin | -0.0382401 |
| PRKD1 | protein kinase D1 | -0.0380155 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0378376 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0371146 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0366282 |
| MPG | N-methylpurine-DNA glycosylase | -0.0362692 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0361388 |
| TNRC6B | trinucleotide repeat containing 6B | -0.03584 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0356989 |
| TOX | thymocyte selection-associated high mobility group box | -0.0355844 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0353433 |
| RASAL2 | RAS protein activator like 2 | -0.0351407 |
| ANK2 | ankyrin 2, neuronal | -0.0350756 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0346025 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0345942 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0341131 |
| PRR16 | proline rich 16 | -0.03401 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0319426 |
| SMYD3 | SET and MYND domain containing 3 | -0.031927 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0319268 |
| CDH19 | cadherin 19, type 2 | -0.0315817 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0311887 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0311681 |
| CUX1 | cut-like homeobox 1 | -0.0311092 |
| MED12L | mediator complex subunit 12-like | -0.0310081 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0309986 |
| ATXN2 | ataxin 2 | -0.0308416 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.030578 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0301533 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0298837 |
| METAP2 | methionyl aminopeptidase 2 | -0.0298129 |
| PDGFC | platelet derived growth factor C | -0.0297478 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0296633 |
| GSE1 | Gse1 coiled-coil protein | -0.0294892 |
| ZNF385D | zinc finger protein 385D | -0.0290788 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0290482 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0287726 |
| LPIN2 | lipin 2 | -0.0286317 |
| TENM2 | teneurin transmembrane protein 2 | -0.0286298 |
| PRTG | protogenin | -0.0284774 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0283872 |
| RCOR1 | REST corepressor 1 | -0.0281306 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0281012 |
| ZNF638 | zinc finger protein 638 | -0.0278865 |
